Cardiac Cell Regeneration — Not too long ago, it was believed that cardiac tissue was uniquely incapable of being regenerated.
Another remarkable example of
cardiac cell regeneration is through what is known as fetomaternal trafficking of stem cells through the placenta.
Not exact matches
We have found that exosomes and the cargo they contain are crucial mediators of stem
cell - based heart
regeneration, and we believe this might lead to an even more refined therapy using the «active ingredient» instead of the entire stem
cell,» said Eduardo Marbán, MD, PhD, director of the Cedars - Sinai Heart Institute and a pioneer in developing investigational
cardiac stem
cell treatments.
«
Cells make costume changes for
cardiac regeneration.»
With the progression of heart
regeneration, these
cells were permanently installed in the muscle tissue and made their contribution to the restoration of
cardiac function.
«
Cardiac progenitor
cells could be ideal for heart
regeneration,» said senior author Sheng Ding, PhD, a senior investigator at Gladstone.
Tenaya is dedicated to addressing heart failure through a multipronged effort that targets the fundamental cellular pathologies present in diseased
cardiac muscle and leverages cutting - edge research in
cardiac regeneration, induced pluripotent stem
cells, and CRISPR technologies.
«Half of the
cells in the heart are fibroblasts, so the ability to call upon this reservoir of
cells already in the organ to become beating heart
cells has tremendous promise for
cardiac regeneration.
The study supports the idea that patients with coronary artery disease may benefit from
cardiac rehab programs, which drive the progenitor
cells into the ischemic tissue, so they can contribute into vascular repair and
regeneration.
Dr. Doris A. Taylor, PhD, Hon DSc, FAHA, FACC, Director of Regenerative Medicine Research for the Texas Heart Institute (THI), is one of the world's leading
cell therapy and
cardiac regeneration scientists.