Sentences with phrase «cardiac myosin»

In our second study we found that heterozygous mutations in genes encoding β - myosin heavy chain (MYH7), α - cardiac actin (ACTC1), cardiac troponin T (TNNT2), cardiac myosin - binding protein C (MYBPC3), and alpha - tropomyosin (TPM1) account for 30 % of cases of isolated LVNC in adult patients (Probst et al., 2011).

Cardiac myosin consumes chemical energy, which it converts into force to power cardiac contraction.

The atomic structures of the cardiac myosin motor domain, with and without bound omecamtiv mecarbil, were determined using X-ray crystallography.

Using noninvasive cardiac magnetic resonance imaging techniques, they were able to confirm the presence of myocardial inflammation in a patient who tested positive for cardiac myosin autoantibodies.

Constitutive phosphorylation of cardiac myosin regulatory light chain prevents development of hypertrophic cardiomyopathy in mice.

Not exact matches

11 mutations were identified in 3 distinct genes: β - myosin heavy chain (MYH7), α - cardiac actin (ACTC), and Troponin T (TNNT2).

For example, clusters containing genes that are upregulated during the course of ES cell differentiation (Table 3) include in order of time of expression: cluster 30 that represents genes which take part in the formation of the three embryonic germ layers during gastrulation, i.e., Goosecoid, Cerberus like 1 homolog, Wnt3, Mesp1, Mixl1, mEomes and Even - skipped 1; cluster 15 containing molecular regulators of early mesoderm development including Bmp2, Bmp5, Msx1, Msx2, Cripto, Tbx20, Hey2, Smad6, Vegfr2 (Kdr), Foxf1 and Hand1; cluster 20, which comprises regulatory and structural genes linked to hemopoiesis such as Gata1, Nfe2, Klf1, Tie1, hemoglobins (Hba - x, Hbb - b1) and Glycophorin A; cluster 12, which is rich in genes involved in cardiac development, e.g., Mef2c, Myl4, cardiac Troponin T2, Tropomodulin 1, myosin binding protein C, Bves, Angiopoietin 1 and Angiopoietin 2; and, cluster 4, which consists mostly of genes associated with neuronal development and differentiation, for example, Neurog1, Neurog2, Olig2, Nkx6.1, Neurod4, Pou3f2, Pou3f4, Cacna2d3, Cacng4, Kcnq2 and EphA5.

Proteins also play structural roles, as the contractile proteins actin and myosin found in cardiac, skeletal, and smooth muscle and as the fibrous proteins collagen, elastin, and keratin.

This panel screens for autoimmunity against heart tissue by checking for myocardial (a protein the heart releases in response to stress) or alpha - myosin (cardiac tissue) antibodies.