Sentences with phrase «cardiomyocyte proliferation»
"Cardiomyocyte proliferation" refers to the process of heart muscle cells, known as cardiomyocytes, multiplying or reproducing to increase their numbers. Full definition
«This idea fits nicely with the findings from a number of groups — that forced expression of cell cycle regulators can induce cardiomyocyte proliferation in mammals,» says Jopling.
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«We are now trying to make adult cardiac fibroblasts more like their embryonic counterparts to induce cardiomyocyte proliferation in the adult.»
Keating notes that «the implication, which isn't proven, but is quite exciting, is that by enhancing human cardiomyocyte proliferation after heart injury, one may be able to enhance cardiac regeneration and reduce cardiac scarring.»
In contrast, in response to injury, the zebrafish heart quickly seals the wound with a fibrin clot, followed by cardiomyocyte proliferation and neovascularization of the new myocardium.
Data in zebrafish demonstrate that PDRM16 has as a dominant positive effect on cardiomyocyte proliferation showing that either activated or repressed levels of activity of PRDM16 impair proliferation.
We want to understand the mechanism and the signals that induce cardiomyocyte proliferation in the zebrafish heart.
Regeneration of cryoinjury induced necrotic heart lesions in zebrafish is associated with epicardial activation and cardiomyocyte proliferation.
But Godwin found that cardiomyocyte proliferation is not the only driver of effective heart regeneration.
After injury, cardiomyocyte proliferation is induced until all lost cardiomyocytes are replaced.