«Further, the study also showed that consuming larger amounts of potassium in the diet counterbalances the adverse affect of high sodium excretion on blood pressure
in cardiovascular disease outcomes.»
«The PURE study is observational in design and does not test directly whether reducing sodium intake in a population
reduces cardiovascular disease outcomes compared to a comparable population, selected at random, that consumes moderate amounts of sodium.»
Wang et al. n - 3 Fatty acids from fish or fish - oil supplements, but not alpha - linolenic acid,
benefit cardiovascular disease outcomes in primary - and secondary - prevention studies: a systematic review.
Aspirin therapy has been recommended to reduce subclinical atherosclerosis and
cardiovascular disease outcomes, including stroke.
«While the PURE study is a major advance in terms of scope and the use of very careful and consistent methodology, it does not allow us to conclude that low sodium intake causes death and
cardiovascular disease outcomes,» she said.
«Importantly, the very large PURE study provides evidence that both high and low levels of sodium intake may be associated with an increased risk of death and
cardiovascular disease outcomes,» said Oparil, director of the vascular biology and hypertension program of the Division of Cardiovascular Disease in UAB's School of Medicine.
Compared to subcutaneous fat, excess visceral fat has a much stronger correlation with adverse metabolic and
cardiovascular disease outcomes.
The logistical difficulties and considerable expense of long term placebo controlled clinical trials of dietary components mean it is unlikely that high level evidence linked to
cardiovascular disease outcome will be obtained in the near future.