Sentences with phrase «cardiovascular system control»

Dr. Saptarsi Haldar's research focuses on how cells in the cardiovascular system control gene expression and how these gene control mechanisms go awry during disease.

Not exact matches

The researchers concluded: «The co-administration of VCO polyphenol with Cd remarkably restored lipid profile and cardiovascular risk ratios and stabilized antioxidant defense systems comparable to control group.

The prone or side sleep position can increase the risk of rebreathing expired gases, resulting in hypercapnia and hypoxia.54, — , 57 The prone position also increases the risk of overheating by decreasing the rate of heat loss and increasing body temperature compared with infants sleeping supine.58, 59 Recent evidence suggests that prone sleeping alters the autonomic control of the infant cardiovascular system during sleep, particularly at 2 to 3 months of age, 60 and can result in decreased cerebral oxygenation.61 The prone position places infants at high risk of SIDS (odds ratio [OR]: 2.3 — 13.1).62, — , 66 However, recent studies have demonstrated that the SIDS risks associated with side and prone position are similar in magnitude (OR: 2.0 and 2.6, respectively) 63 and that the population - attributable risk reported for side sleep position is higher than that for prone position.65, 67 Furthermore, the risk of SIDS is exceptionally high for infants who are placed on their side and found on their stomach (OR: 8.7).63 The side sleep position is inherently unstable, and the probability of an infant rolling to the prone position from the side sleep position is significantly greater than rolling prone from the back.65, 68 Infants who are unaccustomed to the prone position and are placed prone for sleep are also at greater risk than those usually placed prone (adjusted OR: 8.7 — 45.4).63, 69,70 Therefore, it is critically important that every caregiver use the supine sleep position for every sleep period.

Among its many roles, serotonin is involved in the regulation of sleep, and also control of the cardiovascular and respiratory systems.

A potential adrenalinelike drug for weight control must target only the fat - cell receptors to avoid dangerous side effects in the cardiovascular system.

Researchers are still parsing out the precise physiologic effects of cold on the cardiovascular system, but some controlled lab studies run on volunteers have provided clues.

Some of these genes control both cardiovascular development and skeletal development, suggesting the intriguing possibility that the giraffe's stature and turbocharged cardiovascular system evolved in concert through changes in a small number of genes.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

Plenary Lecture: Neuromodulatory Pathways and Central Control of Sympathetic Activity in Hypertension and Heart Failure Frans Leenen of the University of Ottowa will cover the role of various neurotransmitters and neuromodulators in regulating the sympathetic nervous system and how dysregulation can lead to cardiovascular dysfunction and disease.

Many studies have even shown that consuming garlic can be highly beneficial for your cardiovascular system because it regulates the blood pressure and controls the cholesterol levels in the bloodstream — a result of its ability to relax and enlarge the blood vessels.

Just like we can not control our cardiovascular system, we can not control our metabolism.

A lot of people have been asking why I do vacuums... vacuums work transverse abdominals and prevent stomach distension when on stage or competing... they also tighten up the skin and any extra weight around the midsection... also a huge part of training is your cardiovascular system and breathing so when you perform vacuums you strengthen the ability to control your breathing» says Trysten to his fans.

This kind of running sessions will improve muscle strength, enhance the coordination between the nervous system and muscles, strengthen your cardiovascular system, improve blood sugar control and significantly increase fat burning — all of it in much less time than the traditional way!

Physical activity also has a profound effect on our engine, so much so that it can help to maintain our cardiovascular system, our mental health, and it can prevent or control symptoms like osteoporosis, arthritis, prolapse, and incontinence.

Food science: - Sulfer is one of the most abundant mineral elements in the human body - Sulfer is required for the synthesis of glutathione, one of our endogenous (we make our own) antioxidants — an antioxidant that neutralizes free radicals, helps control blood pressure and inflammation, and helps the liver process toxins - Sulfur is essential for Taurine synthesis — taurine is essential to our Central nervous system and the workings of our cardiovascular system - Sulfur helps bind the amino acid chains that form insulin.

The researchers concluded: «The co-administration of VCO polyphenol with Cd remarkably restored lipid profile and cardiovascular risk ratios and stabilized antioxidant defense systems comparable to control group.

The neural control of the cardiovascular system exhibits the complex nonlinear behavior.

It also helps prevent obesity, promote glucose control, and strengthens the cardiovascular system.

Although poor blood sugar control is the cardinal sign of imbalance found in diabetes mellitus, it affects all other major organ systems: cardiovascular, kidney, brain, eyes, you name it.

The hormone «is a powerful antioxidant and mediator of vascular health through its effect on [another hormone] serotonin, which helps regulate our temperature controls, nerves and cardiovascular system,» Rabin explained.

Queensland Aboriginal and Islander Health Council (QAIHC) data show good performance in risk factor monitoring and the management of hypertension and chronic disease.15 Box 2 shows improving performance in completion of health assessments — a first step in prevention activity — over the past 4 years.22 The Torpedo study, a randomised controlled trial of the use of an electronic decision - support system measuring absolute cardiovascular risk, shows ACCHSs outperforming general practices in managing risk.21 Data collected in late 2011 show that the ACCHSs sites had significantly more patients at high risk being prescribed best - practice medications than the general practice sites at baseline, and this gap was sustained through the intervention period (Box 3).23