If the incidence in IGs is similar, we clearly can't afford to cull every affected or
carrier dog from our breeding programs.
Not exact matches
If everyone shares, and if breeders quit throwing stones at each other, and if the scientific community revises its often accusatory stance on
breeding from carriers or even
from affected
dogs, H.E.A.R.T proves it can be done.
In these
breeds, if a
dog has inherited the gene responsible for PRA
from only one parent, it will not develop the disease but will be a
carrier of the trait — meaning that if
bred, it can pass that gene on to its offspring.
You don't want to diminish
breed diversity by eliminating quality
dogs from the gene pool because they are
carriers.
Breeders could then eliminate affected
dogs from their
breeding program and avoid
breeding carriers to
carriers.
The optigen test enables us to
breed from carriers, provided that the
carrier is mated to a clear
dog, in the knowledge that none of the puppies will be affected.
It is acceptable to
breed dogs that are
carriers for PRA, providing the mate has been DNA tested as normal; and puppies produced
from such matings are not at elevated risk to develop the disease.
But without knowing about the affected
dogs in a pedigree, breeders are doomed to continue
breeding proven
carriers and other close relatives, to the misfortune of those who purchase puppies
from these crosses.
For those diseases that lack
carrier screening tests, once a case has been diagnosed the affected
dog should be withdrawn
from breeding.
This is useful for breeders as they can prevent the condition
from being passed on to a litter by not
breeding with a
dog that is a known
carrier of the brittle bone disease gene.
They zealously screened their
dogs, eliminating not only affected animals but the healthy
carriers from the
breeding population.
From high quality pet
carriers for traveling with Fido to ultrasonic plush
dog toys, there's a gift for every budget and every
breed.
CERF Certification for Labradors or Samoyeds with Retinal Folds: The
breeding advice for Labrador Retrievers and Samoyeds diagnosed with «retinal dysplasia - folds» will be changed
from «No» to «Breeder option» if the owner of the
dog provides the CERF office with results of the DNA test for the affected
dog, showing that it is not a
carrier of the oculoskeletal dysplasia (OSD) mutation.
To avoid producing NAD - affected puppies, breeders are encouraged to test their
dogs before they are
bred, and to refrain
from breeding two
carriers to each other.
So far this mutation has been detected in this
breed only, with an estimated
carrier frequency of 25 % based on a large number of samples collected form
dogs originated
from Finland, Sweden, United Kingdom and United States.
To avoid producing GM1 - affected puppies, breeders are encouraged to test their
dogs before they are
bred, and to refrain
from breeding two
carriers to each other.
Now that a genetic test is available, quality
carriers can be
bred to normal - testing
dogs, preventing any affected
dogs from being produced.
We can hop that when
dogs who are born today are ready for
breeding over two years
from now that we can test for
carrier status.
This would allow development of screening tests to identify
carrier and affected
dogs so they may be removed
from breeding programs.
OES do have a 30 %
Carrier rate, which is significant and not far off
from some
breeds that have nearly double the rate of Affected
dogs we see in OES.
To avoid producing SDCA1 - affected puppies, breeders are encouraged to test their
dogs before they are
bred, and to refrain
from breeding two
carriers to each other.
Results
from the 1998 - 99 randomized study and
from general screening during 1992 - 99 indicate that the frequency of affected and
carrier ESSP
dogs has decreased, but PFK deficiency remains a common problem in the
breed.