Through gene therapy, researchers engineered blood - forming stem cells (hematopoietic stem / progenitor cells, or HSPCs) to
carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV - infected cells.
Spontaneous expansion of the CAG repeat stretch in the CAG 140 KI mouse model, which
carries a chimeric mouse / human exon 1 containing around 125 CAG repeats and the human polyproline region inserted in the murine huntingtin gene (Menalled et al., 2003, Hickey et al., 2008), has recently led to a new KI line that carries around 190 CAG repeats (CAG 190 KI) in a congenic C57Bl / 6J background.
The CAG 140 KI mouse model
carries a chimeric mouse / human exon 1 containing around 125 CAG repeats and the human polyproline region inserted in the murine huntingtin gene.
Not exact matches
Anaplastic lymphoma kinase (ALK)-- positive anaplastic large cell lymphoma (ALCL) frequently
carries the t (2; 5)(p23; q35) resulting in aberrant expression of
chimeric nucleophosmin - ALK.
The line 85 mice
carry two transgenes, the mouse / human
chimeric APP / Swe, linked to Swedish FAD and human PS1ΔE9.