Sentences with phrase «carry genes for the proteins»

Humans carry a gene for a protein in cells called apolipoprotein E, which helps clear amyloid - beta from the brain by binding to it and breaking it down.

Not exact matches

So say scientists at Merck, who learned from trials in 2007 that their vaccine, based on a live, weakened adenovirus carrying genes for HIV proteins, was ineffective.

These genes are able to initiate or halt the reading of the structural genes that carry instructions for making proteins.

Since the February breakthrough, PPL Therapeutics of Edinburgh, which collaborates with the Roslin Institute, has produced five lambs from fetal cells that were genetically modified to carry marker genes and genes for human proteins.

In March three separate teams announced that they had zeroed in on a DNA sequence on chromosome 1 that carries the gene for complement factor H, a protein involved in regulating inflammation.

Sickle cell disease is a recessive genetic disorder caused by a single mutation in both copies of a gene coding for beta - globin, a protein that forms part of the oxygen - carrying molecule hemoglobin.

In addition, it was also necessary to introduce a gene for a transport protein that carries fluoromalonate — as fluorine - containing starting material — into the cell.

Clare Wilson reports research on the relationship between genes for proteins that «carry bad cholesterol» and longevity (6 September, p...

Genes may carry information for building proteins, but a host of other factors, including the DNA between genes that doesn't encode proteins, tells them when to make their protGenes may carry information for building proteins, but a host of other factors, including the DNA between genes that doesn't encode proteins, tells them when to make their protgenes that doesn't encode proteins, tells them when to make their proteins.

Both Antarctic and Arctic fish carry antifreeze proteins in their blood, but the genes that code for them not only differ in sequence but arose at different times, since the North Atlantic froze only 2.5 million years ago and the Southern Ocean 10 to 14 million years ago.

To determine whether their method had succeeded, the researchers inserted plasmids carrying a gene that codes for a green fluorescent protein.

Furthermore, gene disruption by gene editing techniques such as CRISPR - CAS resulted in the absence of growth of parasites carrying the mutated gene, indicating that the protein is required for parasite viability.

Gene activity can't be efficiently measured directly, but can be inferred by monitoring RNA, the molecules that carry information from the genes for producing proteins and other cellular activities.

They directly injected into the cerebrospinal fluid of a mouse model of Alzheimer's — adult animals in which plaques were well established — viral vectors carrying genes for one of the three APOE variants or a control protein.

While the genetic code carried in our DNA provides instructions for cells to manufacture specific proteins, it is a second code that determines which genes are in fact activated in particular cell types.

CLPX is a gene that controls mitochondrial unfoldase, an enzyme that carries out a balancing step in actively unfolds selected proteins for «protein quality control» during heme biosynthesis by catalytically activating the rate - limiting step enzyme, ALAS, or degrading ALAS protein.

It will also have to be adapted to carry genes large enough to code for many therapeutic proteins.

Genetic screening later revealed that 24 percent of centenarians from Ashkenazi Jewish populations carry a variant in the CETP gene — an enzyme important for cholesterol metabolism — that reduces the level of the protein CETP in the blood and is linked to a lower prevalence of hypertension, cardiovascular disease and memory loss.

But genes carry instructions for far more proteins than are present in a cell at any one time.

A fault in the gene that codes for the b - haemoglobin protein produces defective haemoglobin that can not adequately carry oxygen round the body.

The exact mutation varies from patient to patient but in 65 percent of cases, the dystrophin gene is missing large sections of DNA called exons, which carry the instructions for protein production.

He notes, however, that researchers should also keep an eye out for proteins other than hemagglutinin and the genes that carry the recipes for them.

A team of biologists led by Gerald Wilkinson of the University of Maryland, University Park, studied a type of Malaysian fly, called Cyrtodiopsis, with a strange genetic battle being waged inside its body: To perpetuate themselves, genes on the fly's X chromosome code for proteins that kill sperm carrying a Y chromosome.

The team also carried out a so - called metagenomic analysis, in which the genomes from all organisms in a sample are sequenced collectively; the great majority of genes they found coded for proteins never seen before.

MicroRNAs lower the levels of proteins such as BDNF by binding to messenger RNA, the molecular middleman that carries instructions from genes to the protein - making machinery of the cell, and tagging it for destruction.

Previously, Semenza's team generated a virus that carries the gene encoding an active form of the HIF - 1 protein, which turns on genes necessary for building new blood vessels.

An international team of scientists, including four from Brown University, conducted and analyzed tests using a «knock - in» mouse carrying a gene for a mutant DNA / RNA binding protein called TDP - 43, which causes a form of inherited ALS in humans.

Human Argonaute - 2 (hAgo2) is known as «slicer» for its unique ability among the 4 human Argonaute proteins to directly cut messenger RNA — which carries the information coded in genomic DNA to make a protein — and thus disable «messages» generated from genes.

Phylogenetic inference was carried out using a partitioned (codon positions 1 — 2 and 3) supermatrix of 20,384 protein - coding genes from Ensembl v72 (80) following quality filtering, using the longest transcript for each gene.

The ACVR1 mutations often occurred with mutations in a gene that carries instructions for making the histone H3.1 protein.

Though every CF patient carries mutations in both copies of the same gene — coding for a protein called cystic fibrosis transmembrane conductance regulator or CFTR — symptoms can vary widely from patient to patient.

They found out that the body's chemistry was changed by changes that happened to more than 700 genes, all carrying information for building protein in the body.

A gene for green fluorescent protein from the jellyfish, Aequorea Victoria, has been inserted into the cats» DNA and is used as a marker for cells carrying a second gene which confers resistance to the feline version of the AIDS virus, the Feline Immunodeficiency Virus (FIV).