Sentences with phrase «carry resistance genes»

We are inadvertently enriching this water with bacteria that carry resistance genes and then exposing people to these bacteria because the water is used to irrigate urban parks.»
If these bacteria happen to come into contact with other microbes that carry resistance genes, those genes can pop over in one step.
«But some of these bacteria carry resistance genes that are known to cause problems in the clinic.
Although the sprayed fields had fewer larvae overall, those survivors were more likely to carry resistance genes, presumably because the double - whammy of Bt crops in neighboring rows and the added Bt spray increased the selection pressure on the insects.
Potatoes engineered to carry a resistance gene withstand late blight (left); normal potatoes shrivel when exposed to the pathogen (center).
Perhaps most alarming to some scientists is that 21 % of the lab moths carried the resistance gene — a rate 10 times higher than that seen in any other bug.
In one case, the CDC network helped diagnose bacteria carrying resistance genes in an Iowa nursing home resident with a urinary tract infection.

Not exact matches

And on the subject of public health, it is worth exploding the number one myth of anti-GM lobbyists that the antibiotic resistance genes carried by some GM crops might lead to devastating human epidemics if transferred to bacteria.
While Wright was not surprised that the bug would carry such genes as antidotes to its own weaponry, he was startled to see that the antidote genes were nearly identical to the resistance genes in vancomycin - resistant enterococcus (VRE), the scourge of American and European hospitals.
Of the Iron Age individuals, three carry at least one Duffy null allele, protecting against malaria, and two have at least one sleeping - sickness - resistance variant in the APOL1 gene.
If a bacterium carries several resistance genes, it is called multiresistant or, informally, a superbug.
More than three fourths of all current antibiotics used to treat human infections are produced by Actinobacteria, which at the same time carry antibiotic resistance genes.
But by investigating the DNA sequence around the resistance genes, the team figured out how the resistance genes transfer occurred through a new mechanism named «carry back,» where the pathogen basically has a primitive form of «sex» with the Actinobacterium and takes up its resistance genes after it dies.
The former target, say, using gene editing techniques to inactivate HIV receptors and achieve resistance of blood cells to the virus (which Sangamo BioSciences is working on in clincial trials) is different than helping parents who both carry genes for Huntington's Disease to have a child that is free of the disease (a change to the genome that would be passed on to future generations and would likely not be very commonly needed).
«Soybean genotypes carrying Rpp1b, Rpp2, Rpp3, and Rpp5a resistance genes, and cultivars Hyuuga and UG5 (carrying more than one resistance gene), were observed to be resistant against most of the African rust strains, and therefore may be useful for soybean - breeding programs in Africa and elsewhere,» Hartman says.
The introduction of penicillin in the 1940s led to the selection of S. aureus strains that carried the methicillin resistance gene.
They found that the phages from antibiotic - treated mice carried significantly higher numbers of bacterial drug - resistance genes than they would have carried by chance.
That's because gut phage from mice treated with one drug carried high levels of genes that confer resistance to different drugs, which means that the phage could serve as backup when bacteria must find ways to withstand a variety of antibiotics.
The genes encoding NDM - 1 and other antibiotic resistance factors are usually carried on plasmids — circular strands of DNA separate from the bacterial genome — making it easier for them to spread through populations.
Using a gene - editing system that can disable any target gene, they have shown that they can selectively kill bacteria carrying harmful genes that confer antibiotic resistance or cause disease.
These crops, being embraced by big agriculture in the U.S., carry genes that imbue them with resistance to herbicides and lace their tissues with a bacterial toxin harmless to humans but fatal to pests that may try to feed on them.
The permits enabled a group at Huazhong Agricultural University in Wuhan to produce two varieties of rice carrying a gene from the Bacillus thuringiensis (Bt) bacteria that provides pest resistance.
Next, researchers isolated the candidate gene and used biotechnical approaches to develop transgenic plants that carried the Sr35 gene and showed resistance to the Ug99 race of stem rust.
The genetically manipulated agrobacteria, carrying the gene for PAT, were then used to infect the crop in which resistance was required.
Last summer, agribusiness giant Syngenta, based in Basel, Switzerland, conducted the first field trials of maize (corn) containing engineered mini-chromosomes, and showed that the mini-chromosomes, which carried multiple genes for insect and herbicide resistance, were stable in the field.
Liu's team however have identified MCR - 1, a resistance gene that is carried on a plasmid — a swappable circle of DNA that can be easily passed between bacteria.
Then the team let loose a special strain of diamondback moth pupa, some of which carried at least one copy of a resistance gene to the Bt toxin.
When insects from such a species carry two copies of a resistance gene, they can survive high doses of Bt.
Into some bacteria they inserted genes for resistance to particular antibiotics; the idea is that only the antibiotic - resistant bacteria are carrying the real message.
But ominously, all the bacteria also carried genes conferring resistance to many other antibiotics, including penicillin and cephalosporins.
«For all of the bacteria we tested, their conjugation rate is sufficiently fast that, even if you don't use antibiotics, the resistance can be maintained — even if the genes carry a high cost.»
At present, the researchers have permission to test the TILs carrying the gene for neomycin resistance on 10 patients suffering from melanoma, a type of skin cancer.
A plasmid in the E. coli carried the gene for extended spectrum cephalosporin resistance, as well as four other resistance genes.
The gene for resistance to extended spectrum cephalosporins is frequently carried on plasmids, often along with multiple genes for resistance to other antimicrobials.
Dr Melita Gordon, from the University of Liverpool's Institute of Infection and Global Health, said: «Importantly, the antibiotic resistance genes, which have previously been carried on a separate genetic package, have now been incorporated into the main chromosome of the bacteria itself, which is likely to make it easier for the Typhoid strain to retain these resistance genes
Plasmids are pieces of independent DNA that often carry multiple antibiotic resistance genes.
use CRISPR - Cas technology to carry out genome - wide screens of gene - gene, gene - drug and cancer - microenvironment interactions in cells and mice in order to explore fundamental biology and to identify drug targets and drug resistance / sensitisation mechanisms.
In pathogenic bacteria, plasmids may carry antibiotic resistance genes.
The widespread use of antibiotics puts selective pressure on only the hardiest bacteria to survive — which often carry virulence or drug resistance genes.
Our gut already contains billions of bacteria carrying resistances to kanamycin and ampicillin, the two most commonly used antibiotic marker genes in GM crops.
Mobile DNA can carry genes for virulence and drug resistance, as well as benign genes.
Most antibiotic resistance probably comes from soil bacteria, and the genes they carry genes can readily be disseminated from one species of bacteria to another on plasmids.
Bacteria will frequently contain small chromosomes called plasmids that commonly carry genes for antibiotic resistance.
The researchers were able to predict the direction of this effect with high accuracy, based on the sequences of bacteria present and the resistance genes they carried in samples taken before treatment.
People who carry a particular type of gene have natural resistance against typhoid fever according to new research published in Nature Genetics.
Epidemiological evidence has always suggested that resistance arose around this period, when the mecA gene encoding methicillin resistance carried on an SCCmec element, was horizontally transferred to an intrinsically sensitive strain of S. aureus.
Several MGEs showed variable distribution across the CC22 phylogeny, including two antimicrobial resistance plasmids (pWBG751 - like and SAP078A - like, carrying erythromycin and heavy metal resistance genes, respectively), a pathogenicity island carrying the enterotoxin C gene and two phage types Sa1int and Sa6int.
Background: Horizontal transfer of mobile genetic elements (MGEs) that carry virulence and antimicrobial resistance genes mediates the evolution of methicillin - resistant Staphylococcus aureus, and the emergence of new MRSA clones.
We postulated that plasmids carrying carbapenemase genes were exchanged between bacterial hosts in sewage, and used short - read (Illumina) and long - read (MinION) technologies to characterize plasmids encoding resistance to antimicrobials and heavy metals.
Antimicrobial resistance genes can be carried on plasmids or on mobile elements integrated into the chromosome.
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