The lack of discrimination in the viruses used to
carry therapeutic genes has been a major obstacle to testing gene therapy in humans.
Even as researchers test these findings in animals, Nabel's team is exploring an intriguing possibility: adding the Ebola virus membrane protein to a harmless virus that could then
carry therapeutic genes specifically to endothelial cells.
Carrying the therapeutic genes, AdV made it into the patients» livers.
To produce an adeno - associated virus that can
carry a therapeutic gene and live on its own, researchers add innocuous DNA from adenovirus during preparation.
Not exact matches
It will also have to be adapted to
carry genes large enough to code for many
therapeutic proteins.