However, the efficacy of these two drugs dropped sharply in recent years due to the global distribution of mutant viruses
carrying drug resistance.
Not exact matches
They found that the phages from antibiotic - treated mice
carried significantly higher numbers of bacterial
drug -
resistance genes than they would have
carried by chance.
That's because gut phage from mice treated with one
drug carried high levels of genes that confer
resistance to different
drugs, which means that the phage could serve as backup when bacteria must find ways to withstand a variety of antibiotics.
use CRISPR - Cas technology to
carry out genome - wide screens of gene - gene, gene -
drug and cancer - microenvironment interactions in cells and mice in order to explore fundamental biology and to identify
drug targets and
drug resistance / sensitisation mechanisms.
Ultimately, the goals are to develop cost - effective genetic tools to determine whether a patient is
carrying parasites that are
drug resistant; to map the emergence of
resistance; to understand the mechanisms and routes of spread of
resistance; and to plan the most effective strategy to control and eliminate the problem.
The widespread use of antibiotics puts selective pressure on only the hardiest bacteria to survive — which often
carry virulence or
drug resistance genes.
Mobile DNA can
carry genes for virulence and
drug resistance, as well as benign genes.
April 3, 2018 • The Centers for Disease Control and Prevention's efforts to control
drug - resistant bacteria finds that the percentage of bacteria
carrying this
resistance is declining.
Simply put, MDR1 is a «multi
drug resistance gene» which certain breeds (including those of mixed breed heritage)
carry that causes sensitivity to certain
drugs.
Residents of China have some of the highest
drug resistance rates in the world, with 42 to 83 percent of healthy people
carrying in their bowels «bacteria that produce extended - spectrum beta - lactamases, which create reservoirs of potential pathogens that can destroy penicillin and most of its variants.»