Sentences with phrase «carrying human genes»

The offspring of monkeys carrying human genes associated with autismlike symptoms had abnormal social behavior, researchers found.

So Daniel Anderson at the Massachusetts Institute of Technology exposed human bone marrow stem cells to biodegradable nanoparticles carrying the human gene for vascular endothelial growth factor (VEGF), which attracts blood vessels to injury sites.

Sun and her colleagues studied transgenic mice that were engineered to carry human genes known to contribute to certain forms of ALS.

As in the first study, a group of young mice carrying the human gene APOE4 showed cognitive impairment on the behavioral level — in other words, they showed signs of damage on the level of spatial memory.

Agricultural and pharmaceutical interests are making animals carry human genes and cloning the results.

Not exact matches

And on the subject of public health, it is worth exploding the number one myth of anti-GM lobbyists that the antibiotic resistance genes carried by some GM crops might lead to devastating human epidemics if transferred to bacteria.

The genome - editing technique earned top honors, in part because of achievements such as «the creation of a long - sought «gene drive» that could eliminate pests or the diseases they carry, and the first deliberate editing of the DNA of human embryos.»

While many humans today carry bits of Neandertal DNA, this is the first time human DNA has been found embedded in a Neandertal's genes.

Genetic results indicate that recent humans carry between 1 - 4 % of Neandertal genes in their genome.

The less adept mice, Rubin's team found, carry extra copies of a previously known human gene called DYRK; a mutated version of an almost identical gene in fruit flies, called minibrain, causes neurological defects.

It seems every one of us carries in our genes a million - year record of past human population size.

The investigators caution the approach is years away from use in humans, but gene therapy carries the promise of restoring hearing in people with several forms of both genetic and acquired deafness.

The Porteus team started with human stem cells from the blood of patients with sickle cell disease, corrected the gene mutation using CRISPR and then concentrated the human stem cells so that 90 percent carried the corrected sickle cell gene.

In a nonhuman primate model geneticist Anthony Chan DVM, PhD, and his colleagues at Yerkes developed, rhesus macaques carry a gene encoding a fragment of mutant human huntingtin.

Studies have shown that more than 50 % of all human cancers carry defects in the p53 gene, and almost all other cancers with a normal p53 function carry other defects which indirectly impair the cancer - fighting function of p53.

Humans might be able to direct gene drives to kill only female mosquitoes (the ones that bite and spread disease), or render the insects incapable of carrying malaria, dengue or other diseases.

Mitochondria carry only a few genes, but they are so plentiful that it's often easier to find their DNA than the single full human genome in a cell's nucleus.

Since the February breakthrough, PPL Therapeutics of Edinburgh, which collaborates with the Roslin Institute, has produced five lambs from fetal cells that were genetically modified to carry marker genes and genes for human proteins.

As a result, many humans today carry 1 to 4 percent Neanderthal genes.

More than three fourths of all current antibiotics used to treat human infections are produced by Actinobacteria, which at the same time carry antibiotic resistance genes.

Since the publication of the human genome sequence in 2001, scientists have found that the so - called junk DNA that lies between genes actually carries out many important functions.

The lack of discrimination in the viruses used to carry therapeutic genes has been a major obstacle to testing gene therapy in humans.

Developing nations had long fought passionately over plant and native human genes, but no one had ever before staked claim to microbes that birds could carry anywhere.

All land vertebrates carry a version of the FOXP2 gene, so some of the Oxford researchers then teamed up with colleagues from the Max Planck Institute for Evolutionary Anthropology in Germany to analyze what is unique about the variant in humans and to track how the gene had evolved in our ancestors.

Last year they announced that modern humans outside Africa carry 1 to 4 percent Neanderthal genes.

But some people thought that bacteria carrying tumor genes would be dangerous for humans.

After that was settled, gene therapists still had to find a suitable virus, or vector, to carry replacement genes into human cells without inciting a damaging or deadly immune response.

The current JBMR study extended that research by using palovarotene in a mouse model carrying the same human gene mutation that causes FOP.

In a report that appears in PLOS BIOLOGY, Dr. Hugo Bellen and his colleagues at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and BCM, and Dr. Chao Tong, at the Life Sciences Institute and Innovation Center for Cell Biology, Zhejiang University in Hangzhou, China, find that mutations of human homologs (genes that carry out similar functions) of cacophony and its partner straightjacket (Cacna1a and Cacna2d2 respectively) cause defects in autophagy in neurons.

Most gene - therapy trials use viruses to deliver genes to a patient's cells, and most of those viruses are retroviruses, which have the ability to neatly splice their genes — and the human gene they're carrying — into a cell's chromosomes.

It may be that the Denisovans interbred with modern humans somewhere in central Asia, and that a later migration carried their genes south - east.

Combining two copies of a mother's genes would theoretically achieve the same thing, yielding an embryo carrying a complete complement of human genes.

Years of diabetes research carried out on mice whose DNA had been altered with a human growth hormone gene is now ripe for reinterpretation after a new study by researchers at KU Leuven confirms that the gene had an unintended effect on the mice's insulin production, a key variable in diabetes research.

UBC Psychiatry Professor Dr. Weihong Song and Neurology Professor Yan - Jiang Wang at Third Military Medical University in Chongqing attached normal mice, which don't naturally develop Alzheimer's disease, to mice modified to carry a mutant human gene that produces high levels of a protein called amyloid - beta.

SOME of us carry mysterious genes that may belong to another species of early human.

They may have lacked a gene mutation that modern humans carry that offers some protection against cancer - causing chemicals found in wood smoke.

These crops, being embraced by big agriculture in the U.S., carry genes that imbue them with resistance to herbicides and lace their tissues with a bacterial toxin harmless to humans but fatal to pests that may try to feed on them.

All organisms, including humans, carry «extinct» genes that no longer work.

people who carry two nonfunctional copies of one of the roughly 20,000 human genes.

The massive project, carried out by a private company in the country, deCODE genetics, has yielded new disease risk genes, insights into human evolution, and a list of more than 1000 genes that people can apparently live without.

Iceland's genomes also yielded a bounty of so - called human knockouts — people who carry two nonfunctional copies of one of the roughly 20,000 human genes.

Humans also carry the HIF - 1α gene, so Johnson suspects that our skin may have the same oxygen - sensing capability.

A study carried out by the Laboratoire Neurobiologie des Interactions Cellulaires et Neurophysiopathologie (CNRS / Aix - Marseille Université), in collaboration with clinicians from Marseilles Public Hospitals (AP - HM) and scientists from the Salk Institute in San Diego (US), has revealed a new gene that plays a crucial role during early development in humans and whose under - expression may induce certain autistic traits.

For the first time, there will be penalties for trafficking in human organs, acting as an intermediary for surrogate motherhood, which is to be banned, and carrying out gene tests not authorised by a court of law.

Results of previous studies in mice of bexarotene's effect on AD have been mixed, and none of those studies were done in mice that carry a human APOE gene and also develop progressive, AD - like pathology.

Humans carry a gene for a protein in cells called apolipoprotein E, which helps clear amyloid - beta from the brain by binding to it and breaking it down.

Human beings, in turn, carry the genes for growing a tail but apparently lack the ancient instructions — lost in 75 million years of evolution — for completing the process.

Further testing confirmed this in human cells, even those carrying the mutated gene responsible for MPNs in patients.

These three monkeys carried a gene encoding a fragment of mutant human huntingtin.

While the scrawny gene has so far only been identified in fruit flies, very similar genes that may carry out the same function are known to be present in all multicellular organisms, including humans.