John E. Burke's work focuses primarily on the kinases and phosphatases that
catalyze the phosphorylation and dephosphorylation of lipid phosphoinositides.
Tyrosine is an amino acid present in proteins that contains a hydroxyl moiety, and kinases are enzymes that
catalyze phosphorylation (addition of a phosphate group) of various substrates in the cell.
Glyceraldehyde -3-phosphate dehydrogenase (GAPDH)
catalyzes the phosphorylation of glyceraldehyde -3-phosphate during glycolysis.
c - Src also
catalyzes the phosphorylation of 12 - lipoxygenase (12 - Lox), which is greatly upregulated in glutamate - challenged neurons.
Not exact matches
Adenosine 3», 5» - monophosphate at a concentration of 5 x 10 - 7 mole per liter causes a 400 percent increase in the rate of
phosphorylation of histone
catalyzed by a partially purified enzyme preparation from rabbit brain.