Sentences with phrase «cause bone marrow»

Pradofloxacin has been shown to cause bone marrow suppression in dogs.
Rarely, agranulocytosis may develop, particularly when used concomitantly with other drugs that can cause bone marrow depression.
Overdosage carries serious side effects, and long term usage can occasionally cause bone marrow suppression leading to reduced blood cell counts.
Albendazole can be used in dogs, but higher doses may cause bone marrow suppression, leaving a dog with permanent immune system deficiency.
In these several cases, oral steroids will be used but they can be extremely dangerous to your puppy's blood and possibly cause bone marrow suppression as well as liver inflammation.
High estrogen levels in an intact female that stays in heat or in a ferret with adrenal gland disease can cause the bone marrow to stop producing red blood cells and cause a moderate to severe anemia.
Kidney disease can also cause the bone marrow to decrease the production of red blood cells and cause a mild to severe anemia.

Not exact matches

Multiple myeloma causes tumors to grow in the bone marrow, preventing the production of normal blood cells.
Right now, scientists think that the reason for this is that the amygdala activity causes more bone marrow, which increases the plaque in the arteries, they become inflamed and then leads to the problems.
A bone marrow aspirate test did not reveal any evidence of the disease, causing the doctors to declare Pagano's cancer in remission.
In the 2000 case of Lisa and Jack Nash, their daughter Molly suffered from a bone marrow deficiency caused by a genetic disorder.
Meet «white slime,» a slurry of chicken part leftovers (bone marrow, bone fragments, cartilege, and even meat) thought to be the cause of the outbreak and imported from Brazil, no less.
Dor Yeshorim contributed to the discovery or confirmation of the genes for Canavan disease; Gaucher disease, which attacks the spleen and liver, causing pain and fatigue; and Fanconi's anemia, a failure of the bone marrow.
On to the blocks were poured a mixture of recombinant human bone morphogenic protein (BMP) powder — a genetically engineered protein that causes cells to ossify or become bone — and liquid bone marrow containing stem cells.
The researchers also examined skin slices from two patients with another form of nerve disease called AL amyloidosis, caused by a bone marrow disorder.
Vitamin C may «tell» faulty stem cells in the bone marrow to mature and die normally, instead of multiplying to cause blood cancers.
Conventional transplant conditioning employs radiation and / or high - dose cytotoxic drugs (also known as alkylators) to destroy the bone marrow and blood and immune cells; it also causes widespread cellular damage throughout the body.
«Uncovering a mechanism causing chronic graft - vs - host disease after bone marrow transplant.»
In MDS, genetic mutations in the bone marrow stem cell cause the number and quality of blood - forming cells to decline irreversibly, further impairing blood production.
(Mackenzie notes that it shouldn't be a problem for her strategy, because she plans to use the same kind of cells as bone marrow transplants, which haven't caused tumors.)
Now a report in this month's issue of Nature Medicine may provide an explanation: A key bone marrow protein causes immune cells in mouse transplant recipients to self - destruct.
Multiple myeloma is a cancer of plasma cells in the blood that causes tumor growths in bone marrow.
Studying mouse monocytes in more detail, the researchers found that the increase in TNF levels that occurs with age causes premature release of immature monocytes from the bone marrow into the blood stream.
That makes strontium 90 a particularly dangerous isotope: it can infiltrate milk, bones, bone marrow, blood and other tissues, where the radiation that it emits can eventually cause cancer.
Bone marrow transplants can cause deadly immune reactions, turning the decision to proceed into a perilous judgment call; HIV patients are better served with today's drug cocktails unless they need the transplant for another disease, experts say.
Now, researchers have for the first time managed to completely replace people's bone - marrow - derived stem cells with those from unrelated donors without causing GvHD.
According to Prof. Shaked, the drug caused inflammatory cells (macrophages) in the bone marrow to enhance the aggressiveness of the disease and provide the cancer cells with resistance to treatment.
Most of the time when the heart is injured, these beneficial immune cells are supplanted by immune cells from the bone marrow, which are spurred to converge in the heart and cause inflammation that leads to further damage.
Because the bone marrow must struggle to make enough hemoglobin, the marrow cavities enlarge, causing deformities especially in the facial bones.
According to cardiologist Stefanie Dimmler at the University of Frankfurt in Germany, degraded telomeres might cause heart disease by impeding the ability of cells from the bone marrow to repair damaged parts of the arterial walls.
The innate system — via stem cells in the bone marrow — mobilizes macrophages, which are a type of white blood cell that swallows and kills invading bacteria like Mycobacterium tuberculosis (Mtb) that causes TB.
The nanoparticles also cause healthy bone marrow, lymph nodes, liver and spleen to appear darker, making tumors stand out.
As part of a clinical trial conducted at Northwestern University in Chicago, Illinois, Ildstad and colleagues extracted bone marrow - producing cells from kidney donors and then removed cells likely to cause GVHD while expanding the number of «facilitating cells» that make an organ recipient's system more receptive.
Antibacterial drugs are sometimes prescribed to treat and prevent infection caused by bone marrow suppression, a side effect of cancer drugs.
Failure to produce new bone marrow can be caused by disease, trauma, or some cancer treatments, and can lead to a significantly higher risk of infections, and the need for blood transfusions.
A disease of bone marrow failure, the condition can cause skeletal deformities and increases cancer and anemia susceptibility.
The only treatment available today is bone marrow transplantation, which requires a compatible donor and can itself cause serious complications.
Previously, stem cells were found only in bone marrow, brain tissue and fetal tissue — sources that have caused both logistical and ethical problems.
This can cause the blood to thicken and keep the bone marrow from making enough healthy blood cells.
Residual leukemic cells that remain in the bone marrow following treatment are a major cause of disease relapse and can also act as an early indicator to the effectiveness of a given treatment strategy.
The therapeutic potential of bone marrow transplantation (BMT) relies on the graft - versus - leukemia (GVL) effect, which is closely associated with graft - versus - host disease (GVHD), the major cause of morbidity and mortality after BMT (1 — 4).
Our physicians and scientists are working on a number of initiatives, including collecting blood and bone marrow from patients to better understand the causes of bone marrow failure syndromes and MDS; exploring possible genetic factors that guide medical care; collecting blood and bone marrow to identify specific proteins that are faulty and how these defects relate to clinical complications and outcomes; and clinical trials to improve stem cell transplants for disorders such as dyskeratosis congenita.
This condition may be present at birth, or it may be caused by certain infections (such as human immunodeficiency virus or HIV), or by certain cancer therapies, such as cancer - cell killing (cytotoxic) drugs, radiation, and bone marrow transplantation.
Myeloproliferative neoplasms are a group of rare disorders of the bone marrow that cause an increase in the number of blood cells.
Malignant cells that remain in the bone marrow following treatment are a major cause of disease relapse.
A transplant swaps out bone marrow with the genetic mutation that causes it to produce sickle - shaped red blood cells with marrow from a person without that mutation.
Stress has been used as a cause - all vector of bodily illness, a perspective that still reigns in the literature including data that demonstrates that perceived stress mobilizes inflammatory immune cells in the bone marrow.
They cause damage to nerves, the immune system, the liver and bone marrow.
Immune System Modulation: Many cancers and many cancer treatments cause a suppression of the bone marrow, the source of blood cells that are the army of the immune system.
April 23, 2017 • After an incorrect dose of a chemotherapy drug for Crohn's disease caused Anne Webster's bone marrow to shut down, she decided that, if she survived, she'd write about her experience.
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