Sentences with phrase «cause cell suicide»

The drugs used in chemotherapy are designed to be toxic to cancer cells usually by inhibiting cell division or causing cell suicide (apoptosis).

Not exact matches

The drug causes tumor cells with a certain mutation — present in about 60 percent of melanomas — to commit suicide.

This triggers a domino effect in the cell's defense system, resulting in the activation of the enzyme caspase - 1, which ultimately causes the induction of pyroptosis, a fiery form of cell suicide.

So alpha - lac may induce apoptosis by directly causing the destruction of DNA from within the cell's nucleus, or it may instigate the suicide - generating caspace cascade through the mitochondria.

The topical anti-fungal drug Ciclopirox causes HIV - infected cells to commit suicide by jamming up the cells» powerhouse, the mitochondria — according to a study by researchers at Rutgers New Jersey Medical School.

The scientists discovered that dinaciclib, by interfering with UPR activation, caused multiple myeloma and myeloid leukemia cells to initiate a form of cell suicide known as apoptosis when exposed to agents that induced ER stress.

Its depletion of nucleotides leaves HIV capable of making just a few incomplete pieces of DNA that cause great harm to their host by stimulating an inflammatory response, causing nearby CD4 + T cells to commit suicide.

The symptoms of many diseases are caused by unwanted cell death, and the pathogens could be triggering abnormal cell suicide.

Ian Jarrold, Head of Research at British Lung Foundation said: «Although still early days, this study is a significant step forward in that it is the first time a drug has been observed causing so - called «cell suicide» in mesothelioma.

The immune misfiring and resulting cell suicide, Mongkolsapaya says, could be a primary cause of dengue hemorrhagic fever.

A TROPICAL disease that can fatally damage the heart may take hold in the human body by causing important immune system cells to commit suicide, according to a Brazilian research team.

One treatment is a vaccine that targets a structure on the outside of cancer cells, while the other is an altered enzyme that breaks apart RNA and causes the cell to commit suicide.

The researchers gave E. coli one last synthetic component: a «suicide gene» that is activated once the pyocin has had some time to build up, causing the cells to burst open and release their toxin.

This causes damage to the molecules that make up the cancer cells and leads them to commit suicide.

In this case, the trigger is a drug that interacts with the protein produced by the «suicide gene,» which metabolizes it into a form deadly to the cell, causing it to commit programmed cell death (apoptosis).

Previous research from the Greene laboratory revealed that the main cause of cell death in HIV involves a programmed cell death pathway called pyroptosis, where the cells commit a particularly fiery form of suicide in self - defense to prevent the spread of the virus.

Scientists have found that sulforaphane causes apoptosis — or programmed suicide — in human breast cancer cells.