Sentences with phrase «cause epigenetic»

But the data demonstrates that tea can cause epigenetic changes in women.

Research has shown that shortages or excesses of food during a person's childhood can cause epigenetic changes that lead to diabetes, obesity and early puberty.

Researchers found that particles in exhaust from cars and trucks can cause epigenetic changes — alterations that affect how genes are switched on and off without changing the DNA sequence itself.

As such, we've already figured out how some factors cause epigenetic changes.

Experiments have also shown how foods can cause epigenetic changes in the womb.

«We know that environmental stress can cause epigenetic changes — modifications to our DNA — that are passed along to future generations,» said Ocorr.

This causes epigenetic changes that can be passed down from generation to generation through affected maternal genes.

Imagine a mother who smokes around her infant daughter, causing epigenetic changes in her daughter that persist into adulthood, even if she moves away.

A new study shows that the choice of fat causes epigenetic changes which in turn could contribute to differences in fat storage.

Still, the researchers can't be certain that the mother's diet caused the epigenetic changes.

Their activation of innate immune signaling caused epigenetic changes that were absolutely necessary for the transformation of somatic cells into iPSCs,» explained Cooke, who holds the Joseph C. «Rusty» Walter and Carole Walter Looke Presidential Distinguished Chair in Cardiovascular Disease Research.

She explains, «We think that HDAC2 serves as a master regulator of memory gene expression, and during Alzheimer's disease it's elevated so it causes an epigenetic blockade if the expression of those memory genes.»

A host of factors, in turn, causes the epigenetic processes that flip different genes on and off.

An evolving view suggests that adrenal fatigue is not a glandular problem, but rather a brain - stress problem.52 Early - life exposure to mercury also causes epigenetic damage to the HPA axis, which can dysregulate the stress response throughout life.

Not exact matches

Epigenetics are heritable changes caused by factors other than DNA.

These epigenetic changes caused the mice to over-respond to estrogen throughout adulthood, long after the BPA exposure.

«Our study suggests that epigenetic changes to cells treated with cigarette smoke sensitize airway cells to genetic mutations known to cause lung cancers,» says Stephen Baylin, M.D., the Virginia and D.K. Ludwig Professor for Cancer Research and professor of oncology at the Johns Hopkins Kimmel Cancer Center.

Epigenetics involves the study of the circumstances that cause genes to be activated or silenced.

In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function using an epigenetic mechanism, where gene changes are caused by influences other than DNA sequences.

Experience may contribute to mental illness in a surprising way: by causing «epigenetic» changes — ones that turn genes on or off without altering the genes themselves

, 1968 Zick Rubin, «The Social Psychology of Romantic Love», 1969 Elliot Aronson, «Some Antecedents of Interpersonal Attraction», 1970 David C. Glass and Jerome E. Singer, «The Urban Condition: Its Stresses and Adaptations — Experimental Studies of Behavioral Consequences of Exposure to Aversive Events», 1971 Norman H. Anderson, «Information Integration Theory: A Brief Survey», 1972 Lenora Greenbaum, «Socio - Cultural Influences on Decision Making: An Illustrative Investigation of Possession - Trance in Sub-Saharan Africa», 1973 William E. McAuliffe and Robert A. Gordon, «A Test of Lindesmith's Theory of Addiction: The Frequency of Euphoria Among Long - Term Addicts», 1974 R. B. Zajonc and Gregory B. Markus, «Intellectual Environment and Intelligence», 1975 Johnathan Kelley and Herbert S. Klein, «Revolution and the Rebirth of Inequality: The Bolivian National Revolution», 1977 Murray Melbin, «Night as Frontier», 1978 Ronald S. Wilson, «Synchronies in Mental Development: An Epigenetic Perspective», 1979 Bibb Latane, Stephen G. Harkins, and Kipling D. Williams, «Many Hands Make Light the Work: The Causes and Consequences of Social Loafing», 1980 Gary Wayne Strong, «Information, Pattern, and Behavior: The Cognitive Biases of Four Japanese Groups», 1981 Richard A. Shweder and Edmund J. Bourne, «Does the Concept of the Person Vary Cross Culturally?»

De Assis, who presented the work at the American Association for Cancer Research meeting in Washington DC, says a fatty diet may cause «epigenetic» DNA modifications that can be passed on to future generations.

The bacteria Helicobacter, believed to be a cause of stomach cancer, has been shown to trigger potentially cancer - inducing epigenetic changes in gut cells.

They also linked two of tobacco smoke's effects — methylation and asthma — suggesting that smoke - induced epigenetic changes could cause asthma as well.

These epigenetic modifications do not change the genetic code, but may contribute to the inhibition of gene expression, causing the cells to produce smaller amounts of the corresponding proteins.

Epigenetics refers to how certain life circumstances can cause genes to be silenced or expressed, become dormant or active, over time.

Stress is thought to cause «epigenetic» changes to genes, which do not alter the sequence of their DNA but instead leave chemical marks that dictate how active genes are.

The researchers proved that this was caused by chemical «epigenetic» changes to parts of the gene that codes for Hnf4a, making it less active than it should be.

With epigenetics we mean such changes in genes that are not determined by changes in the actual DNA sequence, but effects that are superimposed on this, caused for example by environmental effects.

The principle is based on an enzyme, tryptase, that has epigenetic effects that cause cells to proliferate in an uncontrolled manner.

Epigenetic changes beyond a normal expression pattern can cause a variety of diseases.

It might be possible then to link the alterations to environmental changes such as stressful events or diet, which have been shown to cause inheritable epigenetic changes in mice.

The finding is some of the first direct evidence that epigenetic changes can cause cancer.

Hackermüller suspects that non-coding RNAs have an important function at the epigenetic level, for example as a type of cellular long - term memory: «This could also explain why the health effects caused by exposure to hazardous environmental substances often do not emerge until years later.»

After all, it could be argued, what if the epigenetic changes observed in the rats» brains were not directly causing the behavioral changes in the adults, but were merely co-occurring?

A growing body of evidence suggests that environmental stresses can cause changes in gene expression that are transmitted from parents to their offspring, making «epigenetics» a hot topic.

«This means that the epigenetic modifications are likely not caused by substances in the tobacco, but by the hundreds of different elements that are formed when the tobacco is burnt,» says Åsa Johansson, researcher at the Department of Immunology, Genetics and Pathology at Uppsala University and Uppsala Clinical Research Center, who has led the study.

The researchers identified a surveillance mechanism that not only monitors DNA lesions caused by epigenetic reprogramming but also fixes the damage.

«Our results therefore indicate that the increased disease risk associated with smoking is partly a caused by epigenetic changes.

Previously, she and colleagues first implicated mGlu2 in depression when they showed that a promising potential treatment known as acetyl carnitine rapidly alleviated depression - like symptoms in rats and mice by reversing these epigenetic changes to mGlu2 and causing its levels to increase.

In order to understand these effects more precisely, Neher and cowork - ers investigated epigenetic changes in the microglia, i.e. chemical modi - fications to the DNA or its packaging proteins that cause certain genes to become more or less active.

Douglas Thomas, associate professor of medicinal chemistry and pharmacognosy at UIC, and co-workers discovered that nitric oxide plays an important role in epigenetics — heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence.

Nutrient stress and social stress act via the innate immune system and cause the suppression of the immune system that links the proliferation of viruses to transgenerational epigenetic inheritance via everything currently known about microRNAs and adhesion proteins.

Rett syndrome is a neurodevelopmental disorder that is caused primarily by mutations in the gene encoding for MeCP2, an important epigenetic regulator.

Fernald's work suggests that epigenetic processes may cause, rather than simply reflect, changes in dominance status in hierarchically organized species, said Tom Boyce, a professor at the University of California, San Francisco School of Medicine, who was not involved in the study.

If mothers don't get enough folate, their unborn children may lay down an impaired pattern of epigenetic marks that causes their genes to malfunction.

Further, since the disruption of epigenetic mechanisms may cause diseases such as cancer, diabetes and autoimmune disorders, these new findings could have implications for human health.

The main problem is that genetic and epigenetic variables can cause some palms to underproduce.

The readability of genes is controlled by epigenetic factors, namely factors which do not influence the gene sequence directly, but rather cause certain genes and chromosomal segments to be packed in different densities — and thus make them accessible for reading.

So this reverses the symptoms and it also reverses the biological reasons, the biological cause for the symptoms in the progeny which are the epigenetic marks.