Even before the function of the RING portion was known, others had found that defects or deletions specifically in this portion of rapsyn
cause human fetuses to be stillborn, likely because of their inability to breathe, said Mei, a dramatic indicator of the domain's essential role in development of the nerve - muscle connection.
Not exact matches
Since the first
human brain organoids were created from stem cells in 2013, scientists have gotten them to form structures like those in the brains of
fetuses, to sprout dozens of different kinds of brain cells, and to develop abnormalities like those
causing neurological diseases such as Timothy syndrome.
An inflammatory protein that triggers a pregnant mouse's immune response to an infection or other disease appears to
cause brain injury in her
fetus, but not the premature birth that was long believed to be linked with such neurologic damage in both rodents and
humans, new Johns Hopkins - led research suggests.
Using
human fetal «mini-brains» grown in 3 - D cultures, scientists determined that a specific protein produced by the Zika virus changes the properties of neural stem cells in the developing brain of an infected
fetus, potentially
causing microcephaly in newborns (Ki - Jun Yoon, abstract 103.06, see attached summary).
The mouse model mimics aspects of the infection in
humans, with high levels of the virus seen in the mouse brain and spinal cord, consistent with evidence showing that Zika
causes neurological defects in
human fetuses.
Prompted by the newly minted Food Quality Protection Act, the EPA begins to review malathion's safety, focusing on its effect on
fetuses and the
human endocrine and nervous systems, and its potential for
causing cancer.
Working with lab - grown
human stem cells, a team of researchers suspect they have discovered how the Zika virus probably
causes microcephaly in
fetuses.