Sentences with phrase «cause of active gene»

Not exact matches

Davies and Lineweaver suggest that genes active in embryogenesis and switched off later may be reactivated because of damage, causing the accelerated cell division of these rogue cancer cells.

Stress is thought to cause «epigenetic» changes to genes, which do not alter the sequence of their DNA but instead leave chemical marks that dictate how active genes are.

The researchers proved that this was caused by chemical «epigenetic» changes to parts of the gene that codes for Hnf4a, making it less active than it should be.

Then for HARE5, the most active enhancer in an area of the brain called the cortex, they made minigenes containing either the chimp or human version of the enhancer linked to a «reporter» gene that caused the developing mouse embryo to turn blue wherever the enhancer turned the gene on.

«Following the trajectory of type 1 diabetes in the mice, and looking at what genes become active in the microbes and in the immune system, we think we can pinpoint some of these mechanisms that are important, if indeed the microbiome is causing diabetes,» Kostic says.

The study convincingly showed that chromium supplementation «upregulated» a number of genes — causing them to become more active — while others were «downregulated.»