Sentences with phrase «cause uncontrolled proliferation»
They found that AIM2 deficiency causes uncontrolled proliferation of intestinal cells.
https://www.stjude.org/ Not exact matches
Several factors newly discovered to be phosphorylated by GSK - 3 are also known to be mutated in acute myeloid leukemia, a condition in which aberrant splicing causes uncontrolled white blood cell proliferation.
Loss of this function causes tumor formation through uncontrolled stimulation of AKT, an enzyme that stimulates cell proliferation and survival and is often hyperactive in human tumors.
We have appreciated for some time the causes of this uncontrolled proliferation, in particular the roles of proto - oncogenes, tumor suppressors, and their protein products.
All cancers harbour multiple mutations that cause uncontrolled cell proliferation.
Oncogenes — whose protein products, when activated, cause uncontrolled cell proliferation or prevent cells from undergoing apoptosis.