Sentences with phrase «caused by low rate»

Not exact matches

«Due to the stress caused by travel and low survival rates of relocated deer, we believe euthanasia is the most humane option.

Earlier this year, top venture capitalist Bill Gurley sounded the alarmon the «unique circumstances» start - up CEOs find themselves in caused by «the pressures of lofty paper valuations, massive burn rates (and the subsequent need for more cash), and unprecedented low levels of IPOs and M&A».

The industry got a jolt recently when the California Public Employees Retirement System announced it was lowering its historic 7.5 percent expected rate of return in an effort to reduce volatility in its portfolio caused by reaching for risk.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

The only production that could be brought back on line fast is shale oil, but without the extremely low interest rates caused by government meddling, shale drilling will be much more expensive in the future.

Combining this with poor sales growth results in a dismal outlook for earnings 3) the pressure on earnings will continue to hurt capital spending, which is usually just a magnified image of earnings, 4) the same factors will continue to raise default rates, causing earnings problems and debt downgrades among banks and financial companies, 5) earnings shortfalls will also lead to continued job cutbacks, with the unemployment rate rising to at least 5.5 % (indeed, once the unemployment rate has advanced by 0.5 % from its lows, it has never reversed until rising by least 1.5 % off those lows).

Analysts have called it a short - term blip caused by consumers rushing to buy to take advantage of pre-approved mortgages signed 120 days ago when long - term rates were lower.

The adverse impact of the tax plan on munis will likely reduce new issuance by up to 25 % in 2018, probably enough to negate higher yields caused by lower tax rates.

They point to two inflation risk factors: years of setting low rates by the Federal Reserve, and the possibility that recent tax cuts will cause the economy to overheat.

If a rate - lock extension was made necessary by borrower - caused delays — for example, when a borrower didn't return necessary documentation or disputed a low appraisal — then a fee would be charged.

The Deng regime claimed that high rates of population growth, lower deathrates caused by modern medicine and a generally poor and badly educated population had forced China to spend too much on housing, food and employment, and fresh water was becoming a limiting factor.

Principal researcher on the study, Associate Professor of Epidemiology in Trinity, Dr Lina Zgaga, said: «The key question that this work raises is: «When breastfeeding is so strongly recommended across the board by the medical profession, what causes lower rates of breastfeeding following hospital births?

That effectively ignored the problem of falling revenues for the Treasury's coffers caused by a combination of stunted wage growth, lower than expected property transactions and lower interest rates.

Other possible explanations for the decline, which is being caused by a low survival rate of seal pups, include a change to the food supply owing to warming waters; competition for food from large fish called jacks; or the possibility that the reserve is simply too new for its ecosystem to have settled down.

We find that the decline in accretion rate is caused by lower densities of material in the accretion flows, as opposed to a lower surface coverage of the accretion columns.

Known as the «sulfur pearl of Namibia,» this anaerobic species digests organic matter under low - oxygen (or no - oxygen) conditions that are caused by high rates of phytoplankton growth in the Benguela upwelling zone, and the subsequent decay of large masses of dead phytoplankton that have fallen to the seafloor.

It may be possible to reduce all - cause death rates among older adults, including those who are obese, by promoting regular physical activity, such as brisk walking for 30 minutes or more on most days of the week (about 8 kcal / kg per week), which will keep most individuals out of the low - fitness category.43 Enhancing functional capacity also should allow older adults to achieve a healthy lifestyle and to enjoy longer life in better health.

Additionally, the low levels of calcium in the first positive study were mainly associated with higher rates of obesity; the insulin resistance in calcium deficient girls could have been caused by the obesity rather than calcium itself.

When breastfeeding is so strongly recommended across the board by the medical profession, what causes lower rates of breastfeeding following hospital births?

The hormonal changes caused by dieting simply creates an environment where your metabolic rate becomes lowered — and your intake will need to be lowered as a function of this.

The Opotowski team, which found that low vitamin A levels had as great an effect lowering BMD as did high vitamin A levels, suggested that vitamin A deficiency may contribute to increased fracture risk by allowing bone matrix to grow faster than it can be mineralized.12 Indeed, although the net effect of vitamin A is to stimulate osteoclasts and slow the growth of osteoblasts, vitamin A also causes osteoblasts to secrete a variety of enzymes and other proteins that are important to bone mineralization, including osteocalcin, which is a protein that plays a direct role in attracting and binding calcium within the bone matrix.6 By slowing the growth of the matrix but increasing the rate at which it is mineralized, adequate vitamin A helps to ensure sufficient bone densitby allowing bone matrix to grow faster than it can be mineralized.12 Indeed, although the net effect of vitamin A is to stimulate osteoclasts and slow the growth of osteoblasts, vitamin A also causes osteoblasts to secrete a variety of enzymes and other proteins that are important to bone mineralization, including osteocalcin, which is a protein that plays a direct role in attracting and binding calcium within the bone matrix.6 By slowing the growth of the matrix but increasing the rate at which it is mineralized, adequate vitamin A helps to ensure sufficient bone densitBy slowing the growth of the matrix but increasing the rate at which it is mineralized, adequate vitamin A helps to ensure sufficient bone density.

AARON... SIBO is caused by a low metabolic rate.

Since increases in neural drive at short muscle lengths are likely driven by reductions in motor unit recruitment threshold (Pasquet et al. 2005), while increases in neural drive at faster velocities and during concentric contractions are primarily caused by increased rate coding (Pasquet et al. 2006; Harwood et al. 2011; Enoka & Duchateau, 2017), the transfer of neural drive from partial exercises using short muscle lengths could be lower than we might expect, although this would probably depend on whether the strength training exercise was performed with a lighter load, and explosively.

There is little cause to celebrate, however: the positive impact of higher - level questioning is tempered by the low overall rates of occurrence of this practice across all of our K - 6 observations.

While low rates and sluggish wage growth have allowed profit margins to remain at record levels, large U.S. companies continue to struggle with the competitive headwind caused by a stronger dollar, which has hurt revenues and estimates of third quarter earnings.

To determine the real cause of US Bank's lower rate of mortgage complaints, we had to compare the data on a state - by - state basis.

The last two phases were caused, at least in part, by the Federal Reserve's interest rate policy: a strong coupling of rising returns stimulated by low rates, followed by an indication of decoupling when rates rose.

This continued low - rate environment won't stop the slight uptick in mortgage rates, caused by the recent Federal Liberal mortgage rule changes.

This has undoubtedly been caused by the low interest rate policy of the Fed, which depressed returns of such funds.

In the era prior to the CARD Act many issuers applied payments made by cardholders to finance charges and balances with lower interest rates which cause higher interest accrual on the accounts and made it more difficult to pay down the total balances on their credit card accounts faster as the portions of their debt with higher interest rates were carried forward from month to month.

Troy, some significant corrections — e.g. in 2011 and 2015 — were not caused by recessions nor by economic slowdown, and the real rates were then lower than now.

They point to two inflation risk factors: years of setting low rates by the Federal Reserve, and the possibility that recent tax cuts will cause the economy to overheat.

The demand to get approved for bad credit refinance loans has increased, because so many consumers suffer with low credit scores caused by late payments on the adjustable rate mortgages that they can no longer afford.

Uncertainty caused by his election and the promises he made leading up to the election, could prompt the U.S. to keep its interest rate low after all, according to MoneySense.

Variable rates are not evil in and of themselves; home owners simply get themselves in trouble by focusing only on the low interest rate rather than the plan to actually pay back the loan before the bank raises the rate or the market changes cause an increase in the monthly payments of a home owner.

With mortgage rates near their historic lows, fixed rate home mortgages are likely going to be a much better deal if you plan on living in the house for an extended period of time, as when rates reset on ARM loans the prior short - term savings will likely be more than offset by the higher rates for the duration of the loan, which can cause the interest - only loan payment to exceed the amoritizing 30 year fixed rate payments if mortgage rates spike high enough.

Credit card debt, student loan obligations, low rates of health insurance coverage coupled with the looming threat of bankruptcy caused by this lack of insurance all present seemingly unconquerable obstacles to homeownership.

For example, the double - digit inflation of the 1970's was caused by banks keeping interest rates low in an attempt to stimulate a weak economy, at a time when imported inflation from the oil shock was high (leading to stagflation).

Most of the housing bubble was caused by artificially low rates in combination with IO loans and fraud by the mortgage agent since after the initial sale they were not held responsible for the stability of the mortgage.

The sustained low mortgage rates won't stop the minute increase in mortgage rates, caused by last month's Federal Liberal mortgage rule changes.

That year the Liability Hedge Portfolio rose in value, but the fund managers had to lower their discount rate by 0.30 %, which caused its future liabilities to increase.

Pascal Gauthier, an economist at TD Bank, says the current flock to real estate is likely a temporary blip caused by not only the low rates, but also the pent - up demand from people who held off buying last fall and winter while they waited to see if the recession was going to turn into a depression.

Bond markets generally react to the lowering of rates by rallying, causing yields to go down.

With low monthly rates, the Renters Insurance plan covers any personal items that are stolen or damaged by a covered cause of loss and can be replaced at replacement cost, subject to a deductible as low as $ 100.

So Philip, when you previously argued for ultra low interest rates because interest was the big problem caused by debt, were you thinking economies could be maintained without much growth if interest were under control and everything would stay in balance over long period of time?

they caused the housing bubble by lowing rate and subprime loans.

Other common bloodwork changes occurring with hypothyroidism include a mild anemia (low red blood cells), mildly low sodium level, high cholesterol, and a mildly elevated creatinine level (due to decreased blood flow to the kidneys caused by a slower metabolic rate).

Most pets actually chew the bottle but by either route, naphazoline can cause vomiting, low heart rates and arrhythmias, dangerously low or high blood pressure, weakness, hyperactivity and trembling.

Sony had to play catch up with Microsoft in implementing all of these services on its floundering PlayStation 3, as it struggled with low adoption rates caused by its lack of games, a high price tag, and the perception that its online service, while free, just couldn't provide the same solid experience as Xbox Live.

Climate Myth: Climate sensitivity is low «His [Dr Spencer's] latest research demonstrates that — in the short term, at any rate — the temperature feedbacks that the IPCC imagines will greatly amplify any initial warming caused by CO2 are net - negative, attenuating the warming they are supposed to enhance.