Sentences with phrase «caused by the large amount»

Some draft assemblies of the C. krusei genome had been produced prior to these researchers» work, but they were fragmented, a problem caused by a large amount of heterozygosity.

That may be caused by the large amount of plastic on the door panels.

The reason for that is the higher inertia caused by a larger amount of valve train components (lifter - pushrod - rocker arm).

But it is worth noting that though the Fish & Wildlife Dept. has ruled this fish kill a result of natural causes, the Gulf of Mexico has a severe problem with marine dead zones, as New Scientist explains: «Summer dead zones are common in the Gulf of Mexico, caused by the large amounts of fertiliser that get flushed down the Mississippi river, which triggers a dramatic drop in the amount of oxygen dissolved in the water.»

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Large amount of processing and production of the food product, which increase the chance of stainless steel contamination caused by processing and packaging machine failure

Plus, they contain large amounts of antioxidants, substances that protect cells from damage caused by oxidation.Chia seeds look... [Read more...]

The «big money» is often a sign of «sharps» — and causes reverse line movement because the larger, smart, money — overwhelms the large majority of the bets by the general Public (which often bets smaller amounts).

Moreover, when teams are losing by a large amount, they sometimes focus less on the score and more on «cheap - shotting» opposing players; hitting them in an attempt to cause injury.

Bowel cleaning methods can include drinking large amounts of liquids or downing 32 pills, which empty the colon by causing diarrhea.

I interviewed Yeo last week and was surprised by how unabashed Yeo is about the large amount of cash he receives every year from the renewable energy firms whose cause he advances in parliament.

The authors of the review conclude that, due to this strong relationship, and to the amount of alcohol consumed globally, the incidence of and mortality from breast cancer caused by alcohol consumption in general and caused by light alcohol consumption are large.

Erdman adds, «You don't want people thinking they are improving their health by consuming large amounts of the material and are actually causing harm.

A shorter period covered by snow, more spring rain and faster snow melt can combine to release large amounts of runoff that have the potential to stress urban hydrologic systems and cause flooding in urban areas.»

This trait is caused by the accumulation of large amounts of β - carotene that was reported to be controlled by a single recessive gene ore.

The study participants had larger amounts of byproducts caused by this type of oxidative damage in their blood.

«A surprisingly large temperature response is caused by a surprisingly small amount of impurities in snow in polar regions.»

A strong suspicion was that the pale light of will - o» - the - wisp is caused by the ignition of methane, which is produced in large amounts by anaerobic microorganisms.

The administration of IL - 2 using the nanovector reduces the side effects caused by this protein if administered in large amounts to the body.

Research over the last decade, however, has revealed that low levels of carbon monoxide ward off internal injuries caused by such stress, and the team argues that's why elephant seals produce large amounts of the gas.

«The large - scale differences in the structures and transmission characteristics of these proteins — caused by what amounts to seemingly insignificant differences in the positions of a few carbon and hydrogen atoms — are quite remarkable,» Jaroniec said.

The research group, led by molecular biologist Eran Pichersky of the University of Michigan, Ann Arbor, studied two model organisms that are easily manipulated in the laboratory: basil, which produces large amounts of eugenol, and the petunia flower, whose scent is caused by three aromatic compounds including isoeugenol.

Changes in permafrost could cause significant impacts — for example, by causing erosion that damages buildings, roads, or other infrastructure, by causing shifts in ecosystems, and by contributing large amounts of carbon to the atmosphere.

If your gynecomastia is caused by a hormonal imbalance or low testosterone, then you may want to load up on foods that contain large amounts of nutrients that may help boost your testosterone level.

For instance, Bisphenol - A, which is ubiquitous in the environment and large amounts of which can leach into food and liquids from plastic water bottles and the lining of aluminum cans, is shown to significantly block thyroid activity in all tissues except the pituitary, potentially contributing to or causing weight gain, fatigue, and depression but not detected by TSH testing (128,129,132,133,275).

This means that senna may not only cause a large amount of distress, but also could reduce the benefits from other healthy foods by decreasing the amount of them that can be taken in and used by the body.

This can be caused by a number of things, from having a deficient amount of enzymes needed to break down specific carbohydrates, fats or proteins which lead to improper digestion and undigested food in the large intestines which results in gas production and bloating.

The metabolism of fructose by your liver creates a long list of waste products and toxins, including a large amount of uric acid, which drives up blood pressure and causes gout.

You are correct that consuming large amounts of vitamin A by itself will cause trouble and we don't recommend that.

Large amounts of any PUFA, moreover, will cause the cell to make less of this enzymatic machinery by convincing the cell that it is no longer needed.26 This competition and cellular confusion can be avoided altogether by providing small amounts of preformed arachidonic acid and DHA in the diet.

Studies suggest that dietary fiber from whole grains such as wheat and oats increases stool weight.31 The increase in stool weight is caused by the presence of fiber, water that the fiber holds, and partial fermentation of fiber and oligosaccharides, which increases the amount of beneficial bacteria in stool.32 The large intestine responds to the larger and softer mass of residue produced by a higher fiber diet by contracting, which speeds the movement of the bowel contents towards excretion.

Friedman later work found that the rabbits all had large amounts of cortisol in their blood and in their brain caused by these pulsed magnetic fields.

«The high amount of lost instruction time and the large disparities documented in this report are large enough to suggest that at least some students with disabilities, and especially Black students with disabilities, are punished for behavior that is caused by their disability,» Losen wrote in the report.

By tow starting the car you could cause large amounts of unburnt fuel to be pushed through the engine and into the catalytic converter.

When your PCV valve was stuck open, the hard acceleration excited and heated the oil, and the higher levels of blow - by caused by high engine RPM allowed (relatively) large amounts of that oil through the valve into the intake plenum, causing the white smoke you saw.

If you receive large amounts of this interest, or if you have other items on your tax return that are affected by AMT, this portion of your exempt interest distribution may cause you to pay additional tax as a result of the AMT.

Bad credit is caused by a bad credit history, large amount of debt, or other issues on your credit report.

However, in an effort to boost the yield of the MIP and thereby garner more management fees for itself, Fidelity, before the period at issue in the lawsuit, engaged in an imprudent and ultimately unsuccessful investment strategy by, among other things, causing large amounts of the MIP's assets to be held in various forms of securitized debt.

Rodenticides, baits used to kill mice and rats, were found to be the third most harmful substance for pets during the past year, followed by people food like grapes and raisins — which can cause kidney failure in pets — and onion and garlic — which can cause anemia — and veterinarian medications consumed in large amounts.

In large amounts, just about any type of nut could be fatal, either by causing pancreatitis (due to high consumption of fat) or salt toxicity.

It happens when the stomach fills with gas and becomes distended, caused by a dog consuming a large amount of food too quickly, eating from a raised food bowl, or on exercising directly after eating.

An ingredient that is proven harmful in large doses, such as propylene glycol — a synthetic ingredient used to add moisture — can cause irritation and sometimes even organ toxicity in large amounts, but might still be approved by the FDA in very small doses.

Most plants, if eaten in large amounts by cats, can cause GI irritation and vomiting.

According to The Washington Post, the sandstorm is actually a haboob, «caused by the downdrafts of a collapsing thunderstorm complex generated by the Southwest monsoon... When the downdrafts — made up of rapidly descending air — smashed down on the desert ground, they stirred up large amounts of sand and dust subsequently carried forth by the storm outflow.»

He features six special attacks including the Psycho Crusher which is his signature move where he is surrounded by a blue flame and flies at the player causing large amounts of damage.

Fracking has plenty of potential downsides but from the point - of - view of a helicopter the amount of destruction caused by natural gas drilling is minuscule compared to the large - scale devastation from mountain top removal;

In other words, after the immediate increase in temperature caused by a doubling of CO ₂ over 70 years, would the temperature necessarily continue to increase a certain (large or small) amount or could the more slowly acting feedbacks cause it to drop back in the longer term?

Therefore, if switching to natural gas from coal reduces the amount of CO2 you emit, you can tolerate quite a large amount of leakage and still come out ahead, because the warming caused by the leakage will go away quickly once you eventually stop using natural gas (and other fossil fuels), whereas the warming you would get from all the extra CO2 you'd pump out if you stuck with coal would stay around forever.

So even doubling the concentration of atmospheric carbon dioxide would only result in a very small theoretical rise in temperature, since the largest amount of the greenhouse effect caused by atmospheric CO2 has already occurred with the first 20 ppmv concentration.

Two weeks ago we looked at the Triassic - Jurassic mass extinction, some 200 million years ago, that was caused by a large climatic warming event after the break - up of supercontinent Pangaea led to the release of enormous amounts of first [volcanic] CO2 and then methane [from disturbed clathrates — a positive warming feedback] into the atmosphere.