Sentences with phrase «caused glioblastoma»

In December 2016, the New England Journal of Medicine published a study demonstrating that a chimeric antigen receptor therapy (CAR - T) caused glioblastoma regression.

Not exact matches

Northwestern Medicine scientists have identified a small RNA molecule called miR - 182 that can suppress cancer - causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor.

«Our study suggests that if a cancer - causing mutation occurs in the neural stem cell population in the SVZ, it gives rise to the proneural or the neural glioblastoma subtype.

While Zika virus causes devastating damage to the brains of developing fetuses, it one day may be an effective treatment for glioblastoma, a deadly form of brain cancer.

Glioblastoma cells do not naturally produce NY - ESO - 1, so the drug decitabine is given prior to injecting the NY - ESO - 1 targeting T cells in order to cause the tumor cells to express the NY - ESO - 1 target.

Among other theories, it is suggested that the Epstein - Barr virus could be a possible cause of breast cancer and that the cytomegalovirus might cause the malignant brain tumour glioblastoma.

A major study conducted at the Sahlgrenska Academy has now disproved theories of a viral cause for breast cancer and the brain tumour, glioblastoma.

In a 2012 study published in Science, the CUMC team found that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two genes, FGFR3 and TACC3.

However, they did not detect the presence of viruses in breast cancer or glioblastoma multiforme (cancer of the brain), both of which have been suggested to have a viral cause.

Clearly a lot more work needs to be done to understand the precise cause of glioblastoma recurrence after surgery and chemotherapy and how to prevent it.

GSK3β, the first neighbour of β - catenin is a central, highly multi-functional protein known as a key protein difficult to inhibit without causing side effects and toxicity.41 In glioblastoma and NSCLC cancer, previous studies found that the decreased level of FRAT1 influences the GSK3β activity to phosphorylate β - catenin and by that, inhibit the WNT pathway.39, 40 The role of FRAT1 in colon cancer is less known but based on its function in other cancer types and its special influencing position in colon cancer signalling, we point out its relevance as a potential target in colon cancer therapy (Fig. 3d).

While his new venture has Anastos brimming with excitement, there is another cause that constantly remains front and center in his mind: the loss of his mom to glioblastoma, an extremely aggressive form of brain cancer.