This in turn
caused outbreaks of diseases such as measles.
This sometimes
causes outbreaks of diseases such as Cholera in which 1000s of people die, and commonly introduces toxic algae which can cause massive kills of aquatic life.
Not exact matches
Important factors that could
cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability
of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost
of accommodating, announced increases in the build rates
of certain aircraft; 6) the effect on aircraft demand and build rates
of changing customer preferences for business aircraft, including the effect
of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result
of global economic uncertainty or otherwise; 8) the effect
of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution
of key milestones such as the receipt
of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation
of our announced acquisition
of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability
of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk
of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production
of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts
of terrorism; 14) any adverse impact on the demand for air travel or our operations from the
outbreak of diseases or epidemic or pandemic
outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact
of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition
of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect
of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect
of changes in tax law, such as the effect
of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations
of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect
of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability
of raw materials and purchased components; 23) our ability to recruit and retain a critical mass
of highly - skilled employees and our relationships with the unions representing many
of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment
of interest on, and principal
of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness
of any interest rate hedging programs; 28) the effectiveness
of our internal control over financial reporting; 29) the outcome or impact
of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition
of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result
of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks
of doing business internationally, including fluctuations in foreign current exchange rates, impositions
of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
For a century and a half, epidemiology has been an effective strategy for tracing the root
causes of infectious
disease outbreaks — as John Snow demonstrated in 1854, when he painstakingly mapped cases
of cholera in London and eventually traced them to a single contaminated well and water pump in the Soho district
of the city.
The significant increase in the insect - borne
diseases was due in part to the
outbreak of Zika, the mosquito - borne
disease that can
cause severe birth defects.
The
outbreak of Ebola virus in West Africa in 2014, and the worldwide panic it
caused, served as a wake - up call: We as a human race are still extremely vulnerable to fast - spreading, infectious
diseases.
Speaking at the time, Sir Leslie Turnberg, Chairman
of the UK Public Health Laboratory Service (PHLS) commented: ³ The vital importance
of infectious
disease surveillance is clear from the global increase in infectious
diseases and the looming threat
of antibiotic resistance... The effectiveness
of the PHLS is beyond question, and the astonishingly swift identification
of the
cause of the recent
outbreak of salmonellosis from powdered baby milk undoubtedly saved many babies from becoming ill.
Although the City's testing methods did not allow it to determine whether detected organisms were alive or capable
of causing disease, no waterborne
disease outbreaks were reported.
In New York City, the five cooling towers suspected
of causing the
outbreak were cleaned by July 29, before the
disease had even peaked, and once that was completed, the number
of new cases began to decline.
«This summer's
outbreak of Legionnaires»
disease caused concern in communities across the state, and today we are moving forward to help prevent future
outbreaks and keep our neighborhoods safe,» Mr. Cuomo said in a statement.
In the study, a tipping point represented the point at which vaccine coverage declines dramatically due to spreading fear, which could
cause large
disease outbreaks due to a loss
of population immunity.
Collins and his colleagues exposed one culture
of Escherichia coli — some strains
of which colonize the human and animal gut; others
of which are notorious for
causing disease outbreaks — to increasing amounts
of an antibiotic over time.
The latest
outbreak of the Ebola family was discovered in July 2008 as the Philippine Department
of Agriculture was investigating «blue ear
disease» in pigs, a respiratory condition that
causes their ears to turn blue from lack
of oxygen.
Resurgent
outbreaks of infectious
diseases are sickening thousands, and the
causes are societal
«Because the bacterium that
causes TB can lie dormant in someone's lung for months or even years before it
causes disease, we had no way
of knowing whether a TB case we have just diagnosed was a recent infection — suggesting the
outbreak is still going on — or whether the person was infected years ago.»
CDC has investigators in Mexico helping to sort out why that
outbreak has apparently
caused so many more cases
of severe
disease.
A new study suggests that an aggressive reef competitor — the Threespot Damselfish — may have impeded the recovery
of Caribbean long - spined sea urchin populations after a mysterious
disease outbreak caused a massive die - off
of these animals over three decades ago.
Given the symptoms
of the
disease and the rate
of death, «C. novyi makes perfect sense» as the
cause for the Glasgow
outbreak, says Martin Hugh - Jones, a veterinary epidemiologist at Louisiana State University in Baton Rouge.
«Many chemotherapy drugs leave a small amount
of cancer stem cells that
cause a renewed
outbreak of the
disease after a few years.
Currently six coronaviruses are known to
cause disease in people, but so far only two
of them — SARS - CoV and Middle East Respiratory Syndrome coronavirus — have
caused large
outbreaks of fatal illness in people.
In the 1960s, scientists in Taiwan traced an
outbreak of blackfoot
disease,
caused when dying blood cells lead to gangrene, to arsenic - contaminated well water.
Other viral
diseases spread by the same mosquitoes — including dengue and chikungunya — that have
caused massive epidemics south
of the U.S. border have triggered only small
outbreaks in the United States.
Waterborne
diseases are a major
cause of illness in developing countries and are responsible for sporadic and localised
outbreaks of disease in the developed world.
They searched through 60 years
of scientific and newspaper reports to determine two things: first, whether the pathogens
cause visible
disease symptoms or death in wildlife, and second, whether human
outbreaks were preceded or accompanied by evidence
of the
disease in animals.
Polio is back and close to home — this time in the Netherlands, where a new
outbreak has killed one baby and
caused at least 22 cases
of the
disease.
Researchers do not yet know whether the virus is the sole trigger
of the
disease or whether it has an accomplice, but they agree it is a primary
cause of the
outbreak.
In fact, he says, the study
of sewage and river water samples from Japan demonstrates the relative safety
of the vaccine - derived virus: Although virulent vaccine - derived viruses in the environment «are actually a pretty common event,» he says, «we don't see
outbreaks»
of vaccine -
caused disease, even in areas where vaccination coverage is relatively low.
During every recent human
outbreak of the Ebola virus — which often
causes victims to bleed to death — gorilla carcasses have turned up in nearby forests, but scientists were uncertain about the extent
of the
disease's impact.
In 2003, DNA sequencing at the Michael Smith Genome Sciences Centre in Toronto and at the Centers for
Disease Control in Atlanta showed that the virus
causing an
outbreak of severe acute respiratory syndrome (SARS) in China was a new variant
of coronavirus.
Environmental changes
cause stress to our biodiversity, increasing the chances
of disease outbreaks, extinctions, waves
of invasive species and other environmental problems that can occur in stressed ecosystems.
We're thinking that rhinovirus C might be a major, missed
cause of disease outbreaks in chimps in the wild,» Goldberg notes.
Scientists have shown that the first appearance
of wheat stem rust
disease in the U.K. in nearly 60 years, which occurred in 2013, was
caused by the same virulent fungal strain responsible for recent wheat stem rust
outbreaks in Ethiopia, Denmark, Germany, and Sweden.
Scientists do not know if the emergence
of disease outbreaks is due to the introduction
of novel pathogens or due to changes in existing pathogens that may be
caused by deteriorating environmental impacts and / or reduced host resistance.
The
outbreak regions closest to the United States
of leishmaniasis, the
disease caused by the parasite, have come within roughly 300 miles
of the border.
The April 2009 H1N1
outbreak at a Queens, New York, high school was widespread but did not
cause severe
disease, according to an analysis conducted by the New York City Department
of Health and Mental Hygiene and researchers from the Johns Hopkins Bloomberg School
of Public Health.
The frequent occurrence
of disease outbreaks in humans
caused by group A Streptococcus (GAS) is an on - going public health threat.
Periodic
outbreaks of the
disease in sub-Saharan Africa, including an epidemic between 2013 and 2016,
caused major loss
of life and serious economic disruption in the three countries where it occurred: Sierra Leone, Guinea and Liberia.
Periodic
outbreaks of the
disease in sub-Saharan Africa
caused major loss
of life and serious economic disruption.
The U.S. Centers for
Disease Control and Prevention (CDC) is currently investigating a multi-state
outbreak of listeriosis — a serious infection
caused by the bacteria Listeria monocytogenes — that's linked to soft cheese.
In particular, these handouts cover the following specific content about tuberculosis in South Africa: Case study
of one communicable
disease, such as malaria or tuberculosis, at a country scale, either an LIDC or EDC, including: o environmental and human
causes of the
disease o prevalence, incidence and patterns
of the
disease o socio - economic impacts
of the
disease o direct and indirect strategies used by government and international agencies to mitigate against the
disease and respond to
outbreaks.
While the shortage
of rural veterinarians may
cause animal owners to wait longer for care, Dr. Major said he's concerned about what would happen if there was an
outbreak of a serious animal - borne illness such as mad cow or foot and mouth
disease.
They're a powerful source
of experience, knowledge, training and insight that can guide animal shelters to improvements in every area
of animal care, including those that
cause the most ill - will with community members: low adoption rates,
disease outbreaks and poor conditions in the shelter.
CIV is a severe and highly contagious respiratory infection that has
caused many serious
disease outbreaks in 38 states across the country.1 The United States Department
of Agriculture (USDA) granted Zoetis a license for this vaccine in June 2017.
Your misguided and ignorant beliefs are what
cause outbreaks of previously controlled
diseases.
In April 2004, a group
of researchers at the University
of Florida reported that preliminary findings suggested equine influenza virus had jumped the species barrier to dogs and
caused a respiratory tract
disease outbreak, killing eight Greyhounds in January 2004 at a track in Jacksonville, Fla..
In spring 2015, canine influenza made national headlines when it was identified as the
cause of a respiratory
disease outbreak in Chicago - area humane shelters.
This bill: AB 1780 would require the State Public Health Officer to investigate reports
of out -
of - state
outbreaks of communicable
diseases caused by contact with a dog or cat to determine the extent, source, and location
of the
disease and the probable impact it would have on California.
Yet another reason to be extremely wary
of adopting a puppy from a pet store: over the past year, there has been an
outbreak of Campylobacteriosis (an infectious
disease caused by the Campylobacter bacteria) in 12 states, stemming from Petland store locations.
Learn how to define an
outbreak, what common types
of diseases cause outbreaks in shelters, the shelter's ideal response to an
outbreak, and more!
In March 2015 a different strain
of influenza
of avian - origin H3N2
caused a widespread
outbreak of respiratory
disease in pet dogs and dogs in shelters.