Sentences with phrase «caused small mutations»

Next they copied the promising RNA molecules using a technique that caused small mutations in their nucleotide sequences and let these mutated RNA molecules have another go at the reaction.

Not exact matches

But in March, Lichun Tang of China's Beijing Proteome Research Center and colleagues reported using CRISPR / Cas9 to correct disease - causing mutations in a small number of viable human embryos.

And rare mutations that caused salmon to grow an extra fin or an enlarged heart sac, for example, began to turn up in a small fraction of the population, says Short.

The researchers considered two possible explanations: Disease suppression might be the result of one or two additional substitutions on the same gene that buffer the harmful effect of the mutation; or suppression may be caused by numerous small substitutions throughout the genome that form an aggregate «shield.»

Sequencing the genomes of individuals or small families often produces false predictions of mutations that cause diseases.

Next - generation sequencing — the ability to sequence millions or billions of small fragments of DNA in parallel — has revolutionized the biological sciences, playing an essential role in everything from locating mutations that cause human disease to determining how a newly discovered animal fits into the tree of life.

The scientists developed a small - molecule drug compound to prevent abnormal cellular processes caused by a mutation in the C9ORF72 gene.

But because the vinclozolin - induced fertility changes occurred in almost every male rat descended from a treated mother rather than in a small percentage of offspring (as is seen in germ line mutations caused by radiation), Skinner suspects an epigenetic mechanism — a change that doesn't mutate the DNA sequence of an animal, but rather affects how genes are expressed.

Single cell genomics: thinking small by Iain Macaulay We all emerged from a single cell and it only takes a mutation in a single cell to cause disease.

Even the smallest point mutation can cause a normally functioning protein to become useless or less efficient.

Heavy use of antibiotics can cause resistance, which results from a small subset of a bacteria population with a random mutation that allows it to survive exposure to the chemical.

In a pitch - black story of a sexually transmitted «bug» that causes severe mutations in a group of small - town teens, the heightened tensions of adolescence are charged with elements of nightmare exemplified by the highly stylized, drenched - in - shadow atmosphere of Burns» unique visuals.

This was an indirect test based on the identification of a small section of DNA which had been found to be associated with the mutation thought to cause copper toxicosis.

The way the toy poodle breed (and all other «toy» breeds) came into being was through selective inbreeding of the smallest dogs in the litters; essentially the breeders applied their understanding of how mutations may be caused to engineering a specific mutation into a dominant gene.

This finding prompted us to request a small grant from the Tibetan Terrier Health and Welfare Foundation to estimate the relative importance of the C2orf71 mutation as a cause of PRA in Tibetan Terriers.