Sentences with phrase «causes axons»

Previous work by Freeman's lab identified another enzyme, a gene called SARM, which was the first shown to activate a process that causes axons to disintegrate when damaged.

Maniatis and colleagues found that deleting one group of genes in the cluster didn't cause the axon tangling, leaving two possible suspects.

The findings raise the possibility that blocking the Phr1 protein with a drug could keep damaged axons alive and functional when the body would normally cause the axons to self - destruct.

Another stretch — even a moderate one — can cause the axon to go haywire.

Unfortunately, in neurons exposed to toxicants such as the mercury in thimerosal, the structural building blocks of the axon (molecules called tubulin) are disassembled, causing the axon to disintegrate.

A research team led by Michal Schwartz of Israel's Weizmann Institute of Science grew these immune cells in a laboratory and implanted them into rats, and the transplants of the cells caused the axons to regenerate.

Not exact matches

This interrupts the transport of cellular materials along axonal microtubules, causing these materials to accumulate at several points along the axon where they may give rise to varicosities.

Researchers from The Ohio State University have announced they have discovered how blows to the head cause numerous small swellings along the length of neuronal axons.

In 2011 researchers found that these waves of electricity cause neurons in the hippocampus, the main brain area involved with memory, to fire backward during sleep, sending an electrical signal from their axons to their own dendrites rather than to other cells.

When you stimulate a neuron, ions like sodium and potassium and chloride flow back and forth, causing what's called an action potential to travel down the neuron, through the axon, to a synapse.

The other is that the virus itself directly attacks neural cells and destabilizes the myelin sheath around them or damages axons to cause GBS.

Concussions that lead to lasting brain dysfunction cause SNTF to accumulate in vulnerable long axon tracts of the brain, and its blood elevation is a measure of this diffuse axonal injury.

As part of the new study, the researchers showed that intact axons without Phr1 were protected from the damage caused by vincristine, a chemotherapy drug used to treat leukemia, neuroblastoma, Hodgkin's disease and non-Hodgkin's lymphoma, among other cancers.

These electrical pulses travel along specialized extensions called axons to cause the release of chemical signals elsewhere in the brain.

The ISP drug did not cause spinal cord axons known to control movements to cross the scar and reconnect with brain neurons above the injury site.

In the central nervous system, severing axons causes the entire neuron to die quickly, but why they die has been a mystery.

A moderate stretch to an axon, Smith recently found, causes the sodium channels to malfunction.

There are two categories of CMT: those caused by the loss of axons in the peripheral nerves (CMT2) and those characterized by a malfunction in the Schwann cells that make up the myelin sheath, the protective coating that surrounds the nerve fibers and allows them to conduct nerve signals at high speeds (CMT1).

Viral DNA that jumped into our ancestors» genes millions of years ago may contribute to the chewed up axons (blue cylinders) that cause multiple sclerosis.

MS is a debilitating neurological disease caused by the destruction of oligodendrocytes, cells that build the myelin sheaths that surround the signal transmitting axons of neurons.

«In this case, the loss of axons is not caused by disease,» DiAntonio said.

Our goal is to use a new imaging system to monitor damage caused by AD to the brain region that contains the insulated axons (analogous to cables) connecting the neuron cell bodies (analogous to the central processing unit of a computer).

This disruption causes a change in the way light interacts with the tissue, such that the axon bundles exhibit less birefringence and also lower reflectance (back scatter).

This injury severs descending, supraspinal axons and causes chronic deficits in both fore - and hind - limb motor function [32], which can be detected by the grid - walk behavioral test [33].

Therefore understanding the dysfunctional molecular pathways that cause mDA axonal degeneration, and targeting these to protect or re-grow mDA axons, may be a promising therapeutic approach for PD.

He has found that the mutant HD protein causes traffic jams in axons, slowing down traffic in neurons.

Scientists do know that a severed axon will cause a neuron to quickly lose some of its incoming connections from other neurons.

Real schizophrenia is more than 10 % brain use caused by the gene DISC1 causing more linkage between the brain's neurons by the growth of more axons and dendrites than normal.

This can cause injury to the brain's neurons and axons (i.e. the brain's «internal wiring») and prevent them from functioning properly.