Not exact matches
Since the first human
brain organoids were created from
stem cells in 2013, scientists have gotten them to form structures like those in the
brains of fetuses, to sprout dozens of different kinds of
brain cells, and to develop abnormalities like those
causing neurological diseases such as Timothy syndrome.
Zika virus infection in pregnancy
causes severe disability in babies by attacking
stem cells in the developing
brain.
Using human fetal «mini-brains» grown in 3 - D cultures, scientists determined that a specific protein produced by the Zika virus changes the properties of neural
stem cells in the developing
brain of an infected fetus, potentially
causing microcephaly in newborns (Ki - Jun Yoon, abstract 103.06, see attached summary).
But this ability to infect
brain stem cells may prove useful for fighting deadly
brain cancers, many of which are
caused by mutated
stem cells.
«Disturbances to these processes may
cause neuronal
stem cells to develop into different types of
cells or may
cause neurons to migrate to different locations in the
brain, changing neuronal circuitry and potentially leading to behavioral disorders like schizophrenia.»
The impulse starts with excitation of the left retina, then travels down the optic nerve to
cells in the midbrain and
brain stem, which excite neurons near both eyes that
cause the pupils to constrict.
The team injected about 2000 mouse embryonic
stem cells each into the
brains of 25 rats who had previously had their dopamine - producing neurons damaged, which
causes a characteristic tendency to move in circles.
Studying a new type of pinhead - size, lab - grown
brain made with technology first suggested by three high school students, Johns Hopkins researchers have confirmed a key way in which Zika virus
causes microcephaly and other damage in fetal
brains: by infecting specialized
stem cells that build its outer layer, the cortex.
«Now, flies, human
stem cells and autopsied
brains are all telling us the same story here, that this is a fundamental defect
causing disease,» says Rothstein.
• Combining
stem cells with gene therapy, an international collaboration announced the success of a pilot study to treat X-linked adrenoleukodystrophy (ALD), a fatal
brain disease
caused by a mutation of the gene coding for the ALD protein.
Several tests in cultured
cells indicated that ganciclovir would
cause the death of HSV - TK - expressing
stem cells, and testing in the mouse model confirmed that administration of the drug after successful treatment of
brain metastases successfully eliminated therapeutic
stem cells that also expressed HSV - TK.
Previously,
stem cells were found only in bone marrow,
brain tissue and fetal tissue — sources that have
caused both logistical and ethical problems.
Strengthening the link between Zika virus and microcephaly, scientists at UC San Francisco have discovered that a protein the virus uses to infect skin
cells and
cause a rash is present also in
stem cells of the developing human
brain and retina.
The research finds that changes to one of these genes, called Dbx2, could prematurely age
brain stem cells,
causing them to grow more slowly.
By manipulating a specific gene in a mouse blastocyst — the structure that develops from a fertilized egg but is not yet an actual embryo — scientists with the University of Florida's McKnight
Brain Institute and the Harvard
Stem Cell Institute caused cells destined to build an embryo to instead change direction and build the cell mass that leads to the place
Cell Institute
caused cells destined to build an embryo to instead change direction and build the
cell mass that leads to the place
cell mass that leads to the placenta.
When created from the
stem cells of a patient with microcephaly, the
brains - in - a-dish resembled that often - fatal condition; those created from
cells of patients with severe autism indicated that out - of - control neuron growth is the underlying
cause of that disorder.
how can i join a case in columbus ohio, I purchased a yorkiepoo $ 1300 found out she has a nero problem in her
brain stem cell, which also
caused leasins down her spin, took her to osu vet, only place to give mri spinal tap, i am now on 7,000 vet bills.
Likewise, conscious stimulation of effort to move legs from the
brain causes the nerves of the spinal cord to fire, releasing the same chemicals that can stimulate the local
stem cells to heal the damaged spinal cord.