Professor Mignot is internationally renowned for having discovered the mutation that
causes narcolepsy in dogs.
And after decades of puzzling over what
causes narcolepsy's fits of daytime sleep and muscle paralysis, researchers suspect it's a response to an autoimmune disease.
Mignot thinks it probably takes a defective gene and a trigger, like stress or even a virus, to
cause narcolepsy.
The US is now funding a large study of countries that used adjuvanted vaccines in 2009 to see if they may have
caused narcolepsy.
It turned out that, in some people with a specific genetic variant, the vaccine, Pandemrix,
caused narcolepsy and this generated a lot of discussion as to whether other autoimmune diseases may be induced by the vaccine.
But the larger question of what
caused the narcolepsy of Ben and other children remains unresolved.
Not exact matches
A very rare but important
cause of extreme sleepiness (despite getting good quality sleep) is a neurological sleep disorder called
narcolepsy.
Optogenetics also has been used to mimic the underlying mechanisms in
narcolepsy, a disorder that
causes patients to fall asleep at inopportune times.
«It may be that a mild form of
narcolepsy happens much more often than we realize and is an unappreciated
cause of excessive sleepiness in the general population,» says Mignot.
Medication has kept these symptoms largely under control — a good thing, since
narcolepsy can
cause some odd behavior.
Although humans with
narcolepsy do not possess the same genetic mutation, this finding still proved instrumental in unraveling the disease's fundamental
cause.
«I drink enough to use the bathroom every hour,» says Ann Austin, 46, a health - care training and development specialist in St. Louis who has
narcolepsy, which
causes her to have sudden sleep attacks during the day, particularly when she is driving or working at the computer for long stretches.
Conditions such as sleep apnea and
narcolepsy, or just regular sleep deprivation,
cause excessive daytime sleepiness; people will nod off while doing normal daytime activities such as driving or sitting at a desk.
Sleep paralysis is a symptom of
narcolepsy, a sleep disorder that
causes severe, excessive daytime sleepiness, Dr. Kline says.
Narcolepsy can be
caused by numerous factors.
Hormonal changes that occur when an adolescent is going through puberty, as well as the hormonal changes that occur during menopause, are especially known to
cause symptoms of
narcolepsy.
Some sleep disorders can affect a person's ability to fall asleep, such as insomnia, while others might
cause them to feel tired throughout the day and wake up constantly during the night, such as
narcolepsy.
Examples would be insomnia from hormone imbalances and the biochemical imbalances that
cause depression, sleep apnea (the windpipe collapses during sleep blocking air flow which
causes snoring which wakes you up) and
narcolepsy (uncontrollable bouts of sleep during the day).
The reasoning being that it is made for those who suffer specifically from certain sleep related conditions like
narcolepsy or sleep apnea, which
causes them to experience extreme sleepiness or tiredness during the day.
It was agreed that John's
narcolepsy with cataplexy was
caused by his vaccination against H1N1 flu in 2009.
Narcolepsy is a chronic neurological disorder (or dyssomnia), which is
caused by the brain's inability to control sleep and wakefulness.