Its mission is to provide a resource for researchers studying the human brain and the neurobiological
causes of brain disorders.
The findings shed light on the biological
cause of the brain disorder.
Not exact matches
Dementia Definition: A chronic or persistent
disorder of the mental processes
caused by
brain disease or injury and marked by memory
disorders, personality changes, and «impaired reasoning».
Through her own personal life experience, in combination with several years
of intense training with Dr. Stephanie Mines (http://tara-approach.org), Jeanice has come to a deep understanding
of how early overwhelming experiences can influence one's health and personality throughout life and can
cause a variety
of disorders later in life including, but not limited to, repetitive relationship problems, chronic health issues, drug and alcohol addiction, uncontrollable violence and criminal behavior, chemical imbalances in the
brain, fertility issues, severe depression, and an inability to lead a joyful, healthy life.
Until this study, researchers had little insight into the underlying
causes of abnormal functional
brain activity in the
disorder.
Aphasia is a communication
disorder caused by damage to parts
of the
brain that control language, according to the American Speech - Language - Hearing Association.
15 years after a gene defect was found to increase the risk
of schizophrenia 30-fold, scientists have figured out how it might
cause the
brain disorder's debilitating symptoms
They base their argument on mounting evidence showing that the
brains of people who have committed suicide have striking similarities, quite distinct from what is seen in the
brains of people who have similar mood
disorders but who died
of natural
causes.
Now a gene that
causes such
disorders has been found, and it may help unravel a deeper mystery: how it is that the left side
of our
brain controls the right side
of the body, and vice versa.
In the early stages
of Alzheimer's and other so - called proteinopathies —
disorders caused by a malformed protein particular proteins adopt the wrong shape and join with similar misfits to form conglomerates that pile up in the
brain.
The updated guideline covers four neurologic
disorders: spasticity in adults, which is muscle tightness that interferes with movement typically following a stroke, spinal cord or other neurologic injury; cervical dystonia, a
disorder of the
brain affecting neck muscle control that
causes involuntary head tilt or neck movement; blepharospasm, a movement
disorder that
causes the eyes to close uncontrollably; and chronic and episodic migraine.
«Many
brain disorders are
caused by imbalanced neural activity,» says Lih Lin at the University
of Washington, Seattle.
Conditions that
cause the
brain's receptors to stop functioning properly are often mistaken for schizophrenia or bipolar
disorder because these diseases are associated with a decrease in activity
of the NMDA receptors, which control how someone thinks, makes decisions, and perceives the world around them.
The researchers caution that their findings, described online on May 4 in npj Schizophrenia — a new publication from Nature Publishing Group — do not establish a
cause - and - effect relationship between mental illness and yeast infections but may support a more detailed examination into the role
of lifestyle, immune system weaknesses and gut -
brain connections as contributing factors to the risk
of psychiatric
disorders and memory impairment.
Among the
disorders that Balasubramanian has targeted is retinitis pigmentosa, a group
of inherited diseases that
cause degeneration
of the retina (in the back
of the eye where millions
of photoreceptors capture light rays that the
brain turns into images).
«Disturbances to these processes may
cause neuronal stem cells to develop into different types
of cells or may
cause neurons to migrate to different locations in the
brain, changing neuronal circuitry and potentially leading to behavioral
disorders like schizophrenia.»
Finally, experts suggested that he might not suffer from a traditional psychiatric
disorder caused by some inborn biochemical glitch, but from a vasculitis — a swelling
of blood vessels in the
brain, provoked by a hostile outside force.
Prions, whose normal function is unclear, are the likely
cause of mad cow disease and similar
brain disorders in animals and humans.
When I was 8 years old, it
caused this
disorder called hydrocephalus where the tumor is blocking the cerebral fluid in the
brain and that automatically creates pressure within the ventricles and it starts affecting different parts
of the
brain, and in my case it damaged my optic nerve.
Dysfunction in dopamine signaling profoundly changes the activity level
of about 2,000 genes in the
brain's prefrontal cortex and may be an underlying
cause of certain complex neuropsychiatric
disorders, such as schizophrenia, according to UC Irvine scientists.
«Multiple sclerosis: Functional change in
brain as
cause of cognitive
disorders.»
PD is the second most common neurodegenerative
disorder, primarily
caused by the death
of dopamine - containing neurons in the substantia nigra, a region
of the
brain involved in motor control.
Somatic
brain mutations, affecting just pockets
of cells, can be harmful, and have been suggested as a possible
cause of neurodevelopmental
disorders such as autism, epilepsy or intellectual disability (see this review article for further background).
«Antiretroviral treatment only partially penetrates the blood
brain barrier, which means that even if a patient is free
of HIV systemically, the virus is still able to rage on in the
brain,
causing cognitive
disorders and mental decline,» Dr. Dadachova said.
Autism and other specific mental
disorders may be
caused in part by «specific circuits or regions
of the
brain [that] had problems with connectivity,» Krienen says.
The critical role these changes play in
brain development highlights the importance and urgency in understanding neural circuits in more detail and suggests new avenues for investigating the underlying
causes of developmental
disorders such as autism.
«To understand and address the
causes of speech
disorders requires a fundamental understanding
of the
brain circuits and computations involved in learning and controlling speech,» said Dr. Roberts, a Thomas O. Hicks Scholar in Medical Research.
Neurocutaneous
disorders are
caused by abnormal development
of cells in the embryonic stage, leading to tumors in various parts
of the body, including the skin, organs, bones,
brain and spinal cord.
A new study, published online in Pediatric Neurology, evaluated children with TSC, which
causes malformations and tumors in the
brain and other vital organs and has a high prevalence
of autism spectrum
disorders (ASD).
But when the enzymes are over-activated, the
brain produces an excessive level
of neurotoxic byproducts,
causing neuronal dysfunctions that lead to psychiatric
disorders and neurodegenerative diseases.
The research group showed that a molecule, ARHGAP33 regulates synaptic functions and behaviors via intracellular protein trafficking and that the lack
of ARHGAP33
causes neuropsychiatric
disorder - related impaired higher
brain functions.
Eisenstat believes the findings have revealed a new pathway scientists could use to treat developmental
brain disorders by getting to the root
cause of problem.
«A growing body
of evidence suggests that immune system activation, such as that
caused by bacterial and viral infections, can play important roles in many
brain disorders,» explained William Carlezon, PhD, chief
of the Division
of Basic Neuroscience at McLean Hospital, and senior author
of the paper.
McLean Hospital neuroscientists have found that even a brief episode
of immune system activation within days
of birth can
cause persistent changes in sleep patterns concurrent with increases in epilepsy - like
brain activity — a combination
of symptoms common in autism spectrum
disorder (ASD) and other developmental conditions.
«Today it is State
of the Art and we are able to quantify disturbances in serotonin signal transmission in the
brain as the
cause of depression and anxiety
disorders.»
Every year, nearly two million people in the United States suffer traumatic
brain injury (TBI), the leading
cause of brain damage and permanent disabilities that include motor dysfunction, psychological
disorders, and memory loss.
It is commonly misdiagnosed as schizophrenia or bipolar
disorder, but is a form
of treatable
brain inflammation
caused by antibodies that attack the
brain's NMDA receptors.
Cerebral ischemia is a
disorder caused by insufficient blood flow to the
brain and its early detection with MRI contrast agents is vital for survival
of patients.
New research into the
causes of this baffling
disorder is focusing on genes that control the development
of the
brain
Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement
of cellular materials in and out
of a cell's control center — the nucleus — appear to be a direct
cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative
disorder.
Avoiding eye contact is a hallmark
of this developmental
disorder, and researchers have looked for the
cause in the
brain's fusiform gyrus region, active in face recognition.
A new study led by scientists at The Scripps Research Institute (TSRI) is giving researchers a first look at the early stages
of brain development in patients with Fragile X syndrome, a
disorder that
causes mild to severe intellectual disability and is the most common genetic
cause of autism spectrum
disorder.
The
cause of his
disorder has yet to be pinpointed, but it almost certainly stems from a problem in the early development
of his
brain.
A number
of trials have turned up no benefit
of omega - 3 supplementation in bipolar
disorder, a
brain disorder that
causes manic episodes
of elevated mood, energy and cognition, and major depressive episodes
of lowered mood, energy and cognition.
Could plaque buildup in the
brain be the
cause rather than the result
of the debilitating neurogenerative
disorder?
In this neurodegenerative
disorder, the frontal lobes
of the
brain are slowly eaten away,
causing social and mood changes as well as cognitive decline.
Scientists at Washington University School
of Medicine in St. Louis have found a way that corrupted, disease -
causing proteins spread in the
brain, potentially contributing to Alzheimer's disease, Parkinson's disease and other
brain - damaging
disorders.
The invocation
of cell death in this
disorder would explain the clinical feature, the small heads
caused by loss
of nerve cells in the
brain, the team found.
«This study gives a glimpse into the mechanism by which different mutations within the same gene can
cause distinct defects in the
brain, and may help to explain how they may contribute to different disorders,» says Guoping Feng, the James W. and Patricia Poitras Professor of Neuroscience at MIT, a member of MIT's McGovern Institute for Brain Research, a member of the Stanley Center for Psychiatric Research at the Broad Institute, and the senior author of the s
brain, and may help to explain how they may contribute to different
disorders,» says Guoping Feng, the James W. and Patricia Poitras Professor
of Neuroscience at MIT, a member
of MIT's McGovern Institute for
Brain Research, a member of the Stanley Center for Psychiatric Research at the Broad Institute, and the senior author of the s
Brain Research, a member
of the Stanley Center for Psychiatric Research at the Broad Institute, and the senior author
of the study.
Aditi Shankardass is a renowned pediatric neurologist who uses real - time
brain recordings to accurately diagnose children with developmental
disorders and the underlying neurological
causes of dyslexia.