Sentences with phrase «causes of disease expression»

Both consider the underlying causes of disease expression and work to restore greater health and vitality.

Most people now know about Functional Medicine testing as a means of investigating root causes of disease expression.

Not exact matches

Alnylam has been developing drugs that target gene expression in order to prevent to production of certain biological material which can cause devastating diseases.

Telling people that they should suppress their sexuality instead of finding a loving committed relationship causes shame... which leads to unhealthy expressions of their sexuality which leads to emotional trauma, promiscuity, the spread of disease, and sometimes death.

Later in life, overactive MHCI expression might cause excess pruning, leading to the loss of connectivity seen in neurodegenerative diseases such as Alzheimer's, Parkinson's, ALS and multiple sclerosis.

Epigenetic changes beyond a normal expression pattern can cause a variety of diseases.

«RB loss causes a major reprogramming of gene expression, allowing induction of pathways that promote features that induce characteristics of lethal disease,» said senior author Karen Knudsen, PhD, Director of the Sidney Kimmel Cancer Center (SKCC) at Thomas Jefferson University.

The team also recently obtained a grant from the National Medical Research Council in Singapore to pursue a study using the probe to examine the relationship between key Parkinson's disease - linked genes and MAO - B expression and activity to further understand the causes of the disease and illuminate the role of MAO - B in this.

Using this approach, these investigators found that nodes (genes) with high connectivity tend to have lower levels of change in expression than peripheral nodes, consistent with the notion that disease ‐ causing genes are typically not central hubs in a molecular module.

Gata5 a potential diagnostic marker for congenital heart disease The finding also suggests that gata5 could be a potential new diagnostic marker for congenital heart defects, as the researchers demonstrated that gata5 regulates the expression of a gene known as nkx2.5 which, when mutated in humans, causes human congenital heart defects and disease.

We design short interfering RNA (siRNA) molecules that are able to trigger the RNAi pathway and mediate the degradation of specific target messenger RNAs (mRNAs), resulting in the expression of a particular disease - causing gene being inhibited.

In a 2015 Nature Communications paper, Rao, who heads LJI's Division of Signaling and Gene Expression, reported that TET2 / 3 mutations caused myeloid disease resembling acute myeloid leukemia in mice.

Discovered in the late 1970s, the mechanism, called the unfolded protein response, relies on communication between the ER and the cell nucleus: When misfolded proteins, which can cause stress - related diseases, accumulate in the ER, cells counter the surge by triggering a program of gene expression in the nucleus that raises the abundance of ER proteins that foster protein folding and activates a mechanism that degrades protein clumps.

Our siRNA molecules are designed to target a single mRNA in the cell, only affecting the expression of the disease - causing gene.

Our technology is a highly specific and modular platform that enables us to inhibit or «silence» the expression of disease - causing genes, allowing cells to revert to their healthy state.

She explains, «We think that HDAC2 serves as a master regulator of memory gene expression, and during Alzheimer's disease it's elevated so it causes an epigenetic blockade if the expression of those memory genes.»

Additional in vitro and in vivo studies are needed to determine the cause of the specificity of JAK2V617F for myeloid diseases, as second mutations, host modifiers, differential cytokine receptor expression, and other factors may influence the ultimate phenotype of hematopoietic progenitors that acquire the JAK2V617F mutation.

Diversifying selection was particularly evident in the region of wzd / wze genes, which are known to regulate capsule expression and hence the bacterium's ability to cause disease.

Symptoms of illness are viewed not as the cause of disease, but as the expression of the body's attempt at self - healing and should therefore not be suppressed through medical treatment.

Identify and treat the cause: Tolle Causam Symptoms of illness are viewed not as the cause of disease, but as the expression of the body's attempt at self - healing and should therefore not be suppressed through medical treatment.

Functional Medicine is a personalized, systems - oriented model that empowers patients and practitioners to achieve the highest expression of health by working in collaboration to address the underlying causes of disease.

It is difficult to control disorders with a polygenic mode of inheritance as the exact genes which cause such a disease and the non-genetic factors which will influence expression are unknown.

Line - breeding is not the cause of inherited disease, it simply increases the expression of disease genes by bringing them together.