Sentences with phrase «causing cellular damage»
What happens over time is that those free radicals, they can accumulate and then cause cellular damage.
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«TDP43 is a «Goldilocks» protein: too much, or too little, can cause cellular damage,» says first author Sami Barmada, MD, PhD, an assistant professor of neurology at the University of Michigan Medical School and former post-doctoral fellow at Gladstone.
Researchers have uncovered that CT scans can cause cellular damage, saying that it will be in a patient's best interest if their doctor explored dose reduction strategies.
Peroxynitrates results in lipid peroxidation of membranes and cause disturbances in tissue homeostasis that is severe enough to cause cellular damage and eventually cell death (Beattie et al., 2000).
Sleep deprivation causes cellular damage and limits the production of enzymes and hormones your body needs to keep your cells healthy and prevent premature aging.
* This important antioxidant neutralizes free - radicals which cause cellular damage in the body and contribute to the aging process.
If left unchecked, these free radicals cause cellular damage that results in the pain and joint deterioration that occurs in conditions like osteoarthritis and rheumatoid arthritis.
Rutin - also known as rutoside - plays an important role in preventing the creation of free radicals that cause cellular damage.
Antioxidants are touted for their ability to help the body eliminate free radicals, which over time cause cellular damage that can lead to a variety of health problems.
Normal blood sugar levels have been continually revised downward over the past several decades as it's determined that current levels cause cellular damage.
One of the main causes of inflammation is an excess amount of free radicals within the body, which causes cellular damage.
When we are exposed to pollutants and toxins, free radicals cause cellular damage, which in turn contributes to inflammation that can exacerbate conditions like allergies and asthma.
Vet Classics Antioxidants with Coenzyme Q - 10 is a unique blend of highly concentrated antioxidants to help eliminate free radicals that can cause cellular damage.
Free radical activity causes cellular damage that can lead to mutations.
High doses of IR can cause cellular damage.
Not exact matches
Carcinogens may cause cancer by altering cellular metabolism or damaging DNA directly in cells, which interferes with normal biological processes.
In schizophrenia, excessive oxidation — which involves the same type of chemical reaction that causes metal to corrode into rust — is widely thought to cause inflammation and cellular damage.
«Transplanted hematopoietic stem cells reverse damage caused by neuro - muscular disorder: In mouse model of Friedreich's ataxia, a single infusion measurably restored normal cellular functions.»
Conventional transplant conditioning employs radiation and / or high - dose cytotoxic drugs (also known as alkylators) to destroy the bone marrow and blood and immune cells; it also causes widespread cellular damage throughout the body.
A common feature of neurodegenerative diseases such as Alzheimer's, Parkinson's or Huntington's disease are deposits of aggregated proteins in the patient's cells that cause damage to cellular functions.
At the same time, avoiding radiation and alkylators — which cause widespread cellular damage throughout the body — should reduce the risk of long - term HSCT - related complications, such as organ failure and cancer.
Researchers at University of California San Diego School of Medicine report that a single infusion of wildtype hematopoietic stem and progenitor cells (HSPCs) into a mouse model of Friedreich's ataxia (FA) measurably halted cellular damage caused by the degenerative disease.
It regulates a cellular defense response that helps protect cells from oxidative damage caused by environmental toxins or carcinogens.
In this case, he was testing the idea that a buildup of cellular damage caused by oxidation — technically, the chemical removal of electrons from a molecule by highly reactive compounds, such as free radicals — is the main mechanism behind aging.
«Dysfunction of cellular powerplant shakes B - vitamin metabolism, causes genetic damage.»
«Lots of things bind to heparan sulfate to trigger various cellular responses, but when active heparanase levels are high, the receptors become degraded, so bound molecules are released and can cause damage to the local tissues,» said Agelidis.
But until he understands how the cells are stressed in the first place, he won't know much: «We frankly don't have a clue as to how much microwave radiation is needed to cause irreversible damage to cellular proteins.
Harvard Stem Cell Institute scientists at Brigham and Women's Hospital have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions.
But in obesity, accumulation of lipids can cause fatty liver, resulting in cellular damage to the organ.
P16: P16 is perhaps best known as an indicator of cellular senescence, a part of the mechanisms that cause damaged cells or those at the Hayflick limit to become senescent or self - destruct.
New research by scientists shows that when cellular barriers are exposed to metal nanoparticles, cellular messengers are released that may cause damage to the DNA of developing brain cells.
The consensus position in the research community is that tracing back the biochemical chains of cause and effect to root causes, something that is not yet possible for many common medical conditions, will show that all age - related conditions and their complexities are the consequences of a comparatively small number of types of cellular and molecular damage.
Regulatory reform will be necessary to adopt a system based on treating existing pathology to one based on repair of the cellular and molecular damage that causes it, with the outcome being the delay and eventual indefinite postponement of the very onset of such pathology with age.
The damage that it will repair is the one that is causal in senenscence of DNA pathway (such x-ray radiation causing senescence) and oncogenic activated senescence; but not of the type of replicative senescence (that's the domain of telomeres / telomerase / sub-telomeres and epigenetics) and cellular replication / proliferation.
Despite the protection offered by the cellular environment, the integrity of DNA is continuously challenged by a variety of endogenous and exogenous agents (e.g. ultraviolet light, cigarette smoke, environmental pollution, oxidative damage, etc...) that cause DNA lesions, interfering with proper cellular functions, such as transcription, inducing premature cellular death and finally premature ageing and organs dysfunctions.
In order to accelerate the development of therapies to bring aging under full medical control, the Forever Healthy Foundation directly supports cutting - edge research aimed at the molecular and cellular repair of damage caused by the aging process.
And the bright light required for imaging causes photobleaching and other cellular damages.
As their deep pigment suggests, beets contain the antioxidant betalain, which works to repair cellular damage caused by inflammation.
Over time, these lectins can cause serious damage to the intestinal lining and eventually cellular damage within the body.
Brussels sprouts (and other members of the cabbage family) promote the production of glutathione, a great antioxidant to help minimize cellular damage caused by free radicals that are formed from exposure to infectious organisms.
Allicin affects RNA synthesis, inhibiting the reproduction of viruses and bacteria, while phenols and quercetin possess antioxidant properties, inhibiting the cellular damage caused by free radicals.
The combination of these activities helps to minimize the cellular damage and resulting inflammation caused by the various oxidative processes.
He Shou Wu stimulates the production of Superoxide Dismutase (SOD), the most powerful antioxidant in the human body, which works to protect to cellular DNA from oxidative damage, which is widely believed to be one of the primary causes of aging.
Free radical damage caused by electron - seeking, highly reactive, oxidative molecules has been identified as the source of many maladies through mechanisms such as inhibition of telomerase, changes to cellular permeability and DNA damage.
According to the theory, the resulting cellular damage is what essentially causes aging.
Free radical damage causes the cellular degeneration we know as aging.
Previous research has also shown that short - term fasting can produce molecules called free radicals, which are highly reactive chemicals that can cause damage to the body at a cellular and may be associated with impaired organ function, cancer risk and accelerated aging.
In addition, the increase in stress hormones ramps up cellular activity and causes excessive production of free radicals which damage brain cells and further reduce normal GABA production (9).
DNA damage is repairable, but PARPS consume up to 80 % of available NAD + in older humans, meaning it is a major cause of NAD + shortage, leaving less NAD + for cellular respiration, fighting inflammation, and disease (21)
They are highly reactive radicals that can start a chain reaction in the body, such as damaging cellular components, like DNA or the cell membrane, causing cells to function poorly or die.