Sentences with phrase «causing endoplasmic reticulum stress»
The findings reveal a causal chain of events whereby the decreased levels of wolframin protein destabilize the endoplasmic reticulum (causing endoplasmic reticulum stress), thereby reducing calcium release.
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Specifically, under stress, caused by uncontrolled ingestion of fats for example, the endoplasmic reticulum — a cell organelle associated with protein synthesis and folding and lipid metabolism — stops its activity in order to re-establish cell equilibrium.
Without CPEB4, the endoplasmic reticulum is unable to activate the stress response, thus causing hepatocytes to accumulate the lipids produced by the fatty liver.
Target of rapamycin signaling mediates vacuolar fission caused by endoplasmic reticulum stress in Saccharomyces cerevisiae.