Sentences with phrase «causing significant»

The results demonstrated that this new molecule was safe and effective, causing significant improvement in mouse models of both acute uveitis and chronic diabetic inflammation, with no apparent side - effects.

About three to eight percent of premenopausal women suffer from PMDD: a severe form of premenstrual syndrome with a combination of emotional and physical symptoms, causing significant impairment in home, work, and social life.

The researchers found that on average, low salt intake reduced excess extracellular fluid volume by 1 liter, lowered blood pressure by 10 / 4 mm Hg, and halved protein excretion in the urine, without causing significant side effects.

«The loss of key habitat is causing significant conservation challenges for Sumatra — and in particular for this critically endangered species.»

«The cold air mass helps to cool the warm and wet mass, causing significant precipitation at low levels,» explains Gascón, lead author of the study, who reiterates that this situation does not happen very frequently in winter.

Because the device is five to ten times thinner than the smallest commercially available microendoscopes, it can be pushed deeper into the brain tissue without causing significant damage.

Melting permafrost is causing significant changes to the freshwater chemistry and hydrology of Alaska's Yukon River and could be triggering global climate impacts, according to a U.S. Geological Survey report released yesterday.

«We know that with global temperature about 0.9 degrees Celsius above pre-industrial, these changes are already causing significant harm to life.»

Hawkins opposes the pension funds being invested in coal, oil and natural gas companies that are causing significant damage to New York residents.

«A U.S. strike on Iran would be costly, causing significant loss of American life, likely lead to attacks and loss of life in Israel, yet would only postpone Iran's nuclear weapons development by a few years,» her office wrote.

That possibility late Friday was already causing significant divisions after two major union members of Working Families — 32BJ SEIE and CWA Local 1 — said they will not only boycott the Saturday meeting but leave the party.

Buffalo police say a sport utility vehicle struck the south side of the building causing significant damage and the driver fled the scene on foot...

«There is little doubt that systematic tax avoidance is causing significant damage to the British revenue position in the budget.

If it gets this definition wrong, vulnerable people, like torture survivors, could be wrongly detained for immigration purposes, causing significant pain and distress.

He basically says when studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant.

High - powered magnets, if inhaled or swallowed, can stick together within your child's body, causing significant injury.

This battle is over our breasts, and it is causing significant carnage.

Club captain Mikel Arteta had a bony spur removed from his left ankle, which according to the club, had been causing significant discomfort to the Spaniard for months.

During a recent event at the Homestead circuit in Miami an an ex-Jean Alesi Ferrari 412T1 collided with an ex-Gerhard Berger 412T2, causing significant damage to the latter.

In Week 3, Buffalo's high - profile win over New England was a big loss for the betting public, causing a significant overreaction in the sports betting marketplace as 81 % of spread wagers came down on the Bills against the Bengals.

The 3,000 tickets issued to Cologne fans was in line with competition rules but it is clear many more visiting fans arrived, causing significant congestion and disturbance outside the stadium before kick - off.

«The conduct of Coles alleged by the ACCC in these proceedings was capable of causing significant detriment to small suppliers» businesses.

Luckily, our body is designed to produce antioxidants to prevent such threats from causing significant damage to our cells.

Chaos theory now helps us to understand how small and unknown factors can be instrumental in causing significant change in natural phenomena.

Given my rather public skepticism of the thesis that humans are causing any significant climate change, my friend Bob Benne, who is the director of the ethics center at Roanoke College, invited me down to Roanoke to debate Mr. Cizik on these matters.

A petition was organized, stating that «McHugh is tarnishing Hopkins and causing significant harm to LGBT communities within Hopkins and beyond.

«We sincerely apologize for causing significant difficulties to investors,» its Nomura Europe Finance unit told Bloomberg.

In situations like we have just witnessed in the market, prices dropped and investors rushed to get out, causing a significant level of volatility.

In Houston after Harvey and Florida after Irma, wastewater pumping systems failed, causing significant sewage spillage.

For example, a drone crash - landed at the U.S. Open tennis tournament in September, causing significant hand wringing by law enforcement but no injuries.

Given this data, there does appear to be room to increase the minimum wage without causing significant job loss.

«The agency should include and explain the... investigations conducted in Dimock, Pennsylvania; Pavillion, Wyoming; and Parker County, Texas where hydraulic fracturing activities are perceived by many members of the public to have caused significant local impacts to drinking water resources,» states the advisory body's review.

Because pricing is an important driver of profitability, getting it wrong can cause a significant dent in your bottom line, and it can make the difference between remaining profitable or going out of business.

Gina Sanchez of Chantico Global says a North Korean attack, should one occur, isn't likely to cause significant long - term market impact.

As I've noted before, since the start of 2013 — when the «fiscal cliff» calamity was averted at the very last minute with a deal struck between Vice President Joe Biden and Senate Majority Leader Mitch McConnell (R - KY)-- investors have been impervious to the sorts of anxiety attacks that caused significant corrections during the first four years of the bull market.

Economics had expected the November report might be more skewed by the effects of Superstorm Sandy, which caused significant business interruption and damage in several parts of the country in late October and early November.

«A high - fat, high - sugar diet causes significant damage to cognitive flexibility, a new study finds,» according to PsyBlog.

The best evidence we have suggests that a minimum wage this high would cause significant unemployment.

«The data forces a compelling conclusion that Donald Trump's travel ban immediately caused a significant drop in bookings to the USA and an immediate impact on future travel,» said Olivier Jager, CEO of ForwardKeys, in a press release.

When traveling at speeds approaching 800 miles per hour, the tiniest irregularity could cause significant damage.

These next couple of months can cause a significant amount of anxiety, and you may want to reward yourself with a vacation for getting through them.

«This will cause significant strain to that budget balance problem in the long term.»

Although thieves targeted the pipelines leading to and from the facility, they rarely caused significant loss.

«The local talent pool would get reduced so significantly that it is going to cause a significant increase in rates.»

Even so, as a maker of domestic appliances, Dyson does have long experience of running a global supply chain and manufacturing operations — something that has caused significant problems for fresh industry entrants such as Tesla.

This development follows the announcement of a bank bailout plan over the weekend, that has caused significant investor trepidation.

Exciting projects such as those could cause a significant spike in BTC.

What is material enough to cause a significant information advantage?

This situation is exactly what happened in Indiana recently when a private operator's bankruptcy filing threatened to cause significant construction delays on a partially completed road.

The report mentions that the explosion would have caused significant flooding in Kent, but that the nuclear option would be «100 per cent effective» at ensuring «totally irreversible total collapse, rupture [of] tunnel and seabed to cause total flooding and complete collapse of part of tunnel.»