Sentences with phrase «ceftriaxone in»

However, to our knowledge this is the first national study on susceptibility of N. gonorrhoeae to azithromycin and ceftriaxone in China.

Not exact matches

But while an injection of ceftriaxone and an azithromycin pill are supposed to be used in combination, this may not always be the case for all patients.

The results suggest that dual therapy with azithromycin and ceftriaxone, which has been recommended by WHO and many countries to treat gonorrhea, may not prove effective in China.

Neisseria gonorrhoeae (N. gonorrhoeae) strains resistant to azithromycin and / or with decreased susceptibility to ceftriaxone are common in China, according to a prevalence study published this week in PLOS Medicine.

Yin and colleagues found high prevalence of resistance to azithromycin (RTA; 18.6 %; 95 % CI 17.4 % -19.8 %) and decreased susceptibility to ceftriaxone (DSC; 10.8 %; 95 % CI 9.9 % -11.9 %) in the study population.

The latest resistance data from the European Gonococcal Antimicrobial Surveillance Programme suggest stable levels of drug resistance to cefixime, and no significant increase in resistance to another key drug (ceftriaxone).

Patients, enrolled in an NIH funded study, met the following criteria [17]: (1) current positive IgG Western blot using CDC surveillance criteria assessed using a single reference laboratory (University Hospital of Stony Brook); (2) treatment for Lyme disease with at least 3 weeks of intravenous ceftriaxone or cefotaxime that was completed at least 4 months before study entry; and (3) objective evidence of memory impairment as documented by the Wechsler Memory Scale - III compared to age -, sex - and education - adjusted population norms.

Treatment with ceftriaxone, and high or low doses of tigecycline resulted in the same outcome: persistence of non-cultivable B. burgdorferi in tissues of treated mice at 90 days after completion of treatment [14].

The experimental approach utilized a ceftriaxone regimen used by multiple research groups that consistently resulted in persistence of non-cultivable B. burgdorferi following treatment in C3H mice in order to determine the ultimate fate, up to 12 months, of persisting non-cultivable spirochetes.

Collectively, these studies by multiple research groups in multiple mammalian species following treatment with an array of antimicrobial drugs, including doxycycline, ampicillin, amoxicillin, ceftriaxone, and tigecycline, have documented a similar outcome: persistence of non-cultivable B. burgdorferi following antibiotic treatment.

High - level ceftriaxone - resistant gonorrhea, discovered in Japan and called H041, was first isolated from a sex worker's throat.

In lab tests, it was susceptible to spectinomycin and rifampin (unfortunately, oral gonorrhea can only be treated by an injection of ceftriaxone).

Researchers confirmed that other gonococci strains were able to take up the ceftriaxone - resistance gene, showing its potential to spread in the wild population.

This cluster of drug - resistant cases was identified in Honolulu in April and May of this year, with five infections showing «dramatic» resistance to azithromycin, as well as reduced vulnerability to ceftriaxone.

While azithromycin interferes with the bacteria's ability to make proteins, and ceftriaxone causes the cell wall to fall apart, this new drug acts on a crucial protein involved in bacterial DNA replication.

At their conference in September, the CDC announced a cluster of gonorrhea infections that are highly resistant to azithromycin, and that fall prey only to high doses of ceftriaxone.