Sentences with phrase «cell activity at»

Not exact matches

At the conference I met Dr. Kathryn Applegate, who has spent a lot of time thinking about this issue and who looks way too young to have developed computer vision algorithms to measure the remodeling activity of the cell's cytoskeleton.

Or consider Berlin's definition by negation: «The basic sense of unfreedom is that in which we ascribe it to the man in jail, or the man tied to a tree; all that such a man seeks is the breaking of his chains, escape from the cell, without necessarily aiming at a particular activity once he is liberated.»

What all these have in common is that, without any central control, individual units (genes, cells neurons or workers) respond to simple, local information, in ways that allow the whole system (cells, brains, organisms or colonies) to function: the appropriate number of units performs each activity at the appropriate time.

At any given moment, your liver and muscle cells are in possession of enough glycogen to fuel your daily activities.

And consider taking a short walk or doing a few at - home yoga poses for kids with your child to rejuvenate his brain cells; studies have shown that physical activity can help stimulate concentration and cognitive function.

We sat down with our kids and looked closely at their day - to - day lives and then decided on what we would pay for such as clothing, cell phone plans and after - school activities and sports fees and then gave them a budget for the rest such as entertainment (the price of a movie ticket once a month), gifts (birthdays, holidays, church), their craving for school cafeteria food — which we capped at twice a week — plus a small stipend.

At the same time, the activity of hundreds of nerve cells was measured with so - called microelectrode arrays.

«What's really exciting about this was that the activity differences were detected at a critical time in brain development: when neural progenitor cells are proliferating and expanding in number, just prior to producing neurons,» Silver said.

Base oxidation regulates gene activity In cooperation with colleagues at LMU, as well as researchers based in Berlin, Basel and Utrecht, Carell and his group have now shown, for the first time, that a standard base other than cytosine is also modified in embryonic stem cells of mice.

With neural prosthetic technology — microchips that can «listen» to many neurons at the same time — researchers are able to find correlations between the activity of many nerve cells.

Cell assays and animal studies suggest that drugs that restore p53's activity work with not just one mutant form of the protein, but many, says Alan Fersht, a chemist at the University of Cambridge in the United Kingdom.

Researchers at the Humboldt and Charité Universities in Berlin, led by Dr Julie Seibt from the University of Surrey, used cutting edge techniques to record activity in a particular region of brain cells that is responsible for holding new information — the dendrites.

«Our stem cell - based studies indicate that low - calorie sweeteners promote additional fat accumulation within cells compared with cells not exposed to these substances, in a dose - dependent fashion — meaning that as the dose of sucralose is increased more cells showed increased fat droplet accumulation,» said Sabyasachi Sen, M.D., Associate Professor of Medicine at George Washington University in Washington, D.C. «This most likely occurs by increasing glucose entry into cells through increased activity of genes called glucose transporters.»

Researchers at Boston University School of Medicine, Johns Hopkins University and Universiita di Pavia, Harvard Medical School and the University of Leicester collaborated to develop a unique compound, Corin that specifically act to inhibit both demethylase an deacetylase activity in cells.

Co-senior author Professor Jennifer Nichols at the Wellcome Trust - Medical Research Council Stem Cell Institute, said: «Our data allow us to study gene activity in individual cells to an unprecedented level of precision.

Maria Braga, DDS, PhD, and colleagues at the Uniformed Services University of the Health Sciences, F. Edward Hébert School of Medicine, found that activating ASIC1a decreased the activity of nearby cells and reduced anxiety - like behavior in animals.

But scientists at the Lewis Katz School of Medicine at Temple University (LKSOM) now think they can help overcome that problem, thanks to their discovery of a small molecule that selectively kills BRCA - deficient cancer cells by blocking the activity of an alternative DNA repair pathway.

«In this study we found that NF - κB activity is strongly associated with immune system T - cell infiltration in lung cancer,» explained study co-author Dung - Tsa Chen, Ph.D., member of the Biostatistics Department at Moffitt.

Researchers at Columbia University have reported a new approach to visualize glucose uptake activity in single living cells by light microscopy with minimum disturbance.

At the core of this cell behavior is how the loss of that single gene changes activation levels of dozens of other genes, suppressing genes associated with metastatic disease and increasing activity of genes linked to normal tissue.

«This graphene system is able to detect the level of activity of an interfaced cell,» says Vikas Berry, associate professor and head of chemical engineering at UIC, who led the research along with Ankit Mehta, assistant professor of clinical neurosurgery in the UIC College of Medicine.

For the first time, scientists at Newcastle University, UK, have identified that the activity of a key metabolic enzyme found in the batteries of human skin cells declines with age.

Based on years of scientific research into the root causes of the condition, the device uses precisely timed sounds and weak electrical pulses that activate touch - sensitive nerves, both aimed at steering damaged nerve cells back to normal activity.

Plant researchers at VIB and Ghent University have now identified a new molecular network that increases our understanding of stem cell regulation and activity.

Kozai's lab is currently working with Franca Cambi, professor of neurology at Pitt, on a project to understand the role of another type of glial cell on brain injury and neuronal activity.

The team used this change in the variability of the song to look at how the activity of single cells in different parts of the brain altered their activity depending on the social environment.

Since nucleotides are needed to build duplicate copies of a cell's DNA before it can divide, SAMHD1's activity is carefully regulated so that it is active only when the cell is at rest and not dividing.

Indeed, when Sonnenberg's team looked at ILC activity directly, they found that MHCII + ILCs could present foreign antigen to T cells and limit their expansion and pro-inflammatory properties.

In the hippocampus, activity patterns of nerve cells associated with a particular experience, such as running a maze, reoccur but at a faster pace on replay.

To remedy that absence, Golden's lab, along with plant physiologist Takao Kondo and colleagues at Nagoya University in Japan, developed an easy - to - read gauge of changing photosynthetic activity in colonies of the cyanobacterium Synechococcus, a blue - green alga whose one - celled organisms divide as often as once every 5 to 6 hours.

But Clark and her colleagues have taken a new approach: instead of looking during the height of activity, they examined lesion sites after treatment, and identified T cell receptors of cells at these sites that were shared across psoriatic patients but not found in healthy individuals or those with other skin conditions.

Using electrophysiological methods to measure electrical currents through cell membranes, the research group at the Institute for Physiology and Pharmacology, led by Marjan Slak Rupnik, showed that dextromethorphan extends the periods of electrical activity in beta cells.

Researchers at the Cells - in - Motion Cluster of Excellence at the University of Münster (Germany) have now developed a method enabling them to better evaluate and study the activity of inflammatory cells in mice: they have succeeded in genetically modifying precursors of immune cells, then increasing their numbers in a test tube and finally tracking them spatially and temporally in living organCells - in - Motion Cluster of Excellence at the University of Münster (Germany) have now developed a method enabling them to better evaluate and study the activity of inflammatory cells in mice: they have succeeded in genetically modifying precursors of immune cells, then increasing their numbers in a test tube and finally tracking them spatially and temporally in living organcells in mice: they have succeeded in genetically modifying precursors of immune cells, then increasing their numbers in a test tube and finally tracking them spatially and temporally in living organcells, then increasing their numbers in a test tube and finally tracking them spatially and temporally in living organisms.

Scientists at The Institute of Cancer Research (ICR) used the cells of fruit flies, modified with a fluorescent marker that is activated when the cells are put under stress, to identify the signals responsible for driving up activity of the ER.

Scientists at The Institute of Cancer Research, London, identified a molecular trigger responsible for ratcheting up activity of the endoplasmic reticulum (ER)-- the cellular factory that makes the building blocks cancer cells need to keep growing.

The Raman images now show protein activity at neural cell level, but the sensitivity is high enough for detecting areas that are even smaller — as is the case with the brain sample of the healthy person.

These cell activities are regulated by proteins normally found at the cell's membrane.

In healthy people, brain cells link together at a single frequency of electrical activity, like tuning in to a radio station, says Robert McCarley of the VA Boston Healthcare System and Harvard University.

«Now that we know exactly how changes in EMSY spur cancer cell growth, we can start to design therapies to specifically target that activity and hopefully stop it,» says senior author Douglas Levine, MD, director of the Division of Gynecologic Oncology at NYU Langone and its Perlmutter Cancer Center.

Optogenetics works at micro scale, and fMRI covers wide regions of the brain — together this means that scientists have a way to intervene and experiment with entire brain circuits, to finally see how a certain type of brain cell affects the wider global activity of the entire brain.

At the same time T cell activity increased, with a marked increase in the activity of another T cell, CD8, from day 30 to 120.

We already knew that light can stimulate nerve activity, and two years ago Nicholas Smith at Osaka University, Japan, showed that 8 - millisecond bursts of laser pulses could synchronise the pulsing of heart cells in culture.

When the researchers looked at activity at the cellular level in the rats» brains, they saw that individual cells stimulated by the optogenetics would increase firing rates in the PER network and that many cells fired in sync with the optical flicker frequency.

New work at the University of California, Davis, shows for the first time how visual attention affects activity in specific brain cells.

Manuela Martins - Green, a professor of cell biology at the University of California, Riverside, reports that two biological activities are out of control in chronic wound infections.

MYCN and its kin are «transcription factors,» proteins that bind to DNA and influence the rate at which genetic information is used by the cell — essentially serving as brightener / dimmer switches for gene activity.

«It really hasn't been explored when these activity networks — these collections of brain areas that start to work together in the brain — emerge and what types of cells and tissues they emerge in,» says Colin Studholme, Ph.D., a professor with joint appointments in pediatrics and bioengineering at the University of Washington and senior author of the paper.

The researchers used a 2 - photon photolysis technique that can be performed in vivo, together with imaging, to manipulate and monitor neuronal activity at single - cell resolution.

«So, the flexibility of yeast cells does not arise from the activity or inactivity of a single gene,» project head at ISB, Dr. Aimée Dudley, explains.

Amita Sehgal, PhD, a professor of Neuroscience at the Perelman School of Medicine, University of Pennsylvania, describes in Cell a circuit in the brain of fruit flies that controls their daily, rhythmic behavior of rest and activity.