Not exact matches
The
results show that distinct genetic profiles underlie specific memory processes: The study reports, for example, associations between a transporter protein set and the process of learning as well as between a
cell adhesion set and the process of memory storage.
When DIXDC1 is blocked or inactivated, focal
adhesions become small and numerous,
resulting in hundreds of small «hands» that pull the
cell forward in response to extracellular cues.
Their studies indicate that the two conditions common in sickle
cell disease, dramatically increase red blood
cells»
adhesion to the lining of blood vessels walls and the debilitating pain crises that can
result.
The
resulting endothelial
cell lines described in this study retain their phenotype after repeated passage, require minimal nutritional support and, importantly, may be useful for identifying factors that regulate endothelial
cell proliferation and tumor
cell adhesion in different anatomical regions.
Given our model
results, we speculate a relationship between
adhesion and the variance of
cell lineage cluster size, which could determine the ability of microbes to cope with variability in nutrient patchiness [62 — 65].
Resulting applications from the science could include surface coatings with tunable functions for use in bone repair or regeneration,
cell adhesion, antifouling, antibacterial activities, and more.
These
results support data suggesting that excess HS oligosaccharides impair function of cellular
adhesion molecules and disrupt normal polarization and orientation of cultured MPSIIIB mouse astrocytes or neural stem
cells [52].
Taken together, these
results strongly suggest that the LPA2 signaling modulates T
cell motility in the confined environments at least partly in an integrin - independent manner and may also act on
cell adhesion to prevent over-
adhesion to the substrates.