Sentences with phrase «cell adhesion within»
Not exact matches
They compared Ras - transformed cells with and without p53 and observed that those expressing p53 were less invasive and formed fewer focal adhesions, the molecular linkages that connect the structural scaffolding within the cell to the extracellular matrix that surrounds the cell.
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This, in turn, enhanced cellular contractility and adhesion, allowing cells to retain their shape and position within stiff extracellular matrices.
The laboratory currently pursues four integrated research objectives: 1) Defining how dynamic regulation of adhesion and migration controls metastasis, 2) Identification and characterization of the metastatic cell populations within a primary tumor, 3) Experimental modeling of metastasis in a clinically relevant manner, and 4) clinical implementation of molecular markers of migration as biomarkers of tumor progression and metastasis.
The diagnostic domains of two major cell — cell adhesion superfamilies, the cadherins and the immunoglobulins, are present in Monosiga within the extracellular region of putative transmembrane proteins31, 34 (Supplementary Note 8.8).