Sentences with phrase «cell analysis in»

For these reasons, mass cytometry has emerged as the leading technology for high - content single - cell analysis in health and disease.

She has generated multiple genetically altered mouse strains to facilitate lung stem cell analysis in vivo.

Discover how these scientists are incorporating real - time, label - free cell analysis in screening and validation to identify therapeutic targets

Not exact matches

I won't reveal yet who my favorites are, but I will say that these young scientist - founders came up with very creative solutions for preventing infections in some common surgeries, tackling resistance in targeted antibody drugs, improving gene vectors for cell therapies, helping the vision - impaired «see» faces and better read their environments, imaging hard - to - see spots in the lungs and other organs, improving genetic risk analysis, and expediting the logistical operations of hospitals.

If he talks about the event character (1 / 10th of a second in length and all that) of the self, it is because he thinks that is what analysis of self - consciousness itself discloses and not because he means to construct the self out of subhuman individuals or organisms (Shalom's «event - cells»).

This independence can be directly demonstrated by an analysis of the mechanism of cell division and combination in sexual reproduction.

A cell - unit of reality, or «actual - entity,» is analyzable, according to Whitehead, «genetically» as well as «morphologically» (PR 219/256), and he himself carried out these two analyses in two separate parts of his main work (PR sections III, IV).

These cells are then sent to a genetics lab for analysis while the embryos are safely frozen and stored in our IVF lab.

We found that: a) lactation stage must be defined biochemically (such as Na: K ratio), not by day of lactation, b) lactation stage influences RNA quality, quantity, and potential immune cell contamination, c) immediate processing and hard, fast centrifugation yield better quality RNA, and d) additional washing of the milk fat layer is not necessary for the analysis of mature milk samples and does not decrease immune cell contamination in colostrum samples.

Total urinary As was measured by collision cell ICP - MS using germanium as an internal standard.30 Arsenic species were obtained by a high - performance liquid chromatography GP50 pump (Dionex Corp) and a PRP100X column (Hamilton Co) connected to a collision cell ICP - MS.29, 31 - 33 Approximately 10 % of samples were run in duplicate for both analyses.

When similar analysis was performed on the db mice, it was found that the disrupted db gene was responsible for encoding a protein that functions as a leptin receptor: When it binds circulating leptin at the cell surface, it sets in motion a biochemical cascade inside the cell.

Rather than carry out conventional bulk analysis of cells, the research group examined individual cells, screening them for the presence of two critical gene mutations common in AML, known as FLT3 and NPM1.

This cell - type - specific analysis was essential to demonstrate that there is a close interplay between epigenetic mechanisms and the spatial folding of the DNA in the cardiomyocytes» nucleus.

And a new analysis of the STEP trial, published last November in Proceedings of the National Academy of Sciences USA, provides a warning that the very vectors (adenoviruses, which are also employed in other vaccine development work) used to distribute the inactive HIV strains can actually make the immune system more vulnerable to infection by recruiting susceptible T cells to mucous membranes, where they are more likely to be infected during sexual activity.

An in - depth genetic analysis, performed with the participation of graduate students Tal Lupo and Lihee Asaf, pointed to a gene called WNT5B, which was revealed to be the factor prompting stem cells to differentiate into lymphatic cells.

Analysis showed that within the moss protonema cells, more that 85 % of the lead had accumulated in the cell walls, with smaller amounts being found in organelle membranes and inside the chloroplasts where photosynthesis occurs.

Chan's laboratory uses genomic analyses to identify neoantigens — novel peptides found only in tumors that arise from mutations accumulated by cancerous cells.

In cancer research, our goal is to be able to start with a sample of human tissue, extract many cells of interest, and perform genetic analysis upon each of them separately.

The analysis revealed that the human genome is organized into large pieces of low or high epigenetic stochasticity, and that these regions correspond to areas of chromosomes that are structurally different in the cell nucleus.

In the latest issue of the journal Cell Systems, Berger and colleagues present a theoretical analysis that demonstrates why their previous compression schemes have been so successful.

O. M. Pereira - Smith and J. R. Smith, Genetic analysis of indefinite division in human cells: Identification of four complementation groups.

An analysis of the HPV16 genome from 5,570 human cell and tissue samples revealed that the virus actually consists of thousands of unique genomes, such that infected women living in the same region often have different HPV16 sequences and variable risks to cancer.

The other significant finding of the study, says Garrett Jenkinson, Ph.D., assistant research scientist at the Johns Hopkins Whiting School of Engineering who carried out much of the analyses, was that this variability goes haywire in cancer cells, which may display significant regional differences in methylation stochasticity compared to normal cells.

Based on the little eyewitness information they could collect, Charlottesville police in 2003 started approaching dark - skinned men with a request for what some call get - lucky swabs — swipings from the inner cheeks of nonsuspects to collect cells for DNA analysis.

Carlo Croce, a cancer researcher at Ohio State University in Columbus, and his colleagues created a diagram of interacting miRNAs for normal body cells by connecting them according to which genes they target and the function of those genes, in a way similar to analyses of human social networks.

The NB activity in Alberta is far ranging, with such research as self - assembled nanostructures (M. J. Brett), single - cell cancer analysis (L. M. Pilarski), computational modeling (D. Wishart), micro-total analysis systems or lab on a chip (D. J. Harrison), cell identification and manipulation (K. Kaler), and microsystems and medical diagnostics (Backhouse).

«Our analysis revealed that the differences between tame and aggressive foxes may lie in cells in the anterior pituitary gland, which can change their shapes to communicate with one another about when it's time to release stress hormones,» Hekman said.

The study, «Spectrophotometric analysis at the single - cell level: elucidating dispersity within melanic immortalized cell populations,» was supported in part by the Mizzou Advantage program, an initiative that fosters interdisciplinary collaboration among faculty, staff, students and external partners to solve real - world problems in four areas of strength identified at the University of Missouri, including Food for the Future, One Health / One Medicine, Sustainable Energy and Media of the Future.

Recent statistical analyses of confidential bank data suggest that mountains of riches aren't in your future but that a jail cell is.

The analysis of the ploidy of minichromosomes in cells that are released from arrest demonstrates that the sister molecules are properly segregated when the cell cycle block is removed.

Small noncoding microRNAs (miRNAs) have been found in such abundance that they have been christened the «dark matter» of the cell, a view reinforced by an analysis of the small RNAs found in Arabidopsis (pp. 1567 and 1525).

Their analysis of more than 4,000 individual tumor cells, the largest effort to date in brain tumors, finds three developmental categories of cancer cells — one resembling neural stem cells and two characterized by sets of genes indicting paths towards differentiation.

Solar power fares badly too, in Ausubel's analysis: «The amount of energy generated in [one quart] of the core of a nuclear reactor requires [2.5 acres] of solar cells.»

Biochemist Radhey Gupta of McMaster University in Canada proposes that a bacterium and an archaean fused to form the first eukaryote, based on his analysis of a pair of slow - changing genes found in what may be one of the oldest cells with a nucleus, Giardia lamblia.

Such analyses have tied Alzheimer's risk to several genes involved in innate immunity — the body's immediate defenses that indiscriminately attack pathogens and other foreign molecules and cells.

HPV is detected using a DNA analysis that looks for characteristic sequences from the 13 high risk strains of the virus in the cervical cell sample.

In the final analysis, it seems clear that Geron is not going for the obvious play, pairing stem cells and nuclear transfer to pursue human clones.

The analysis found that cyclists had 2.3 times more soot in their airway cells.

Scholl is upbeat that the transplanted cells still appear safe and says that analysis of the cells in the recipients» eyes are «indeed an indication that something is happening.»

Further analyses of NMP in cultured cells and live mice confirmed the solvent's antimyeloma activity.

Isoflavones have been shown to slow the growth of breast cancer cells in laboratory studies, and epidemiological analyses in East Asian women with breast cancer found links between higher isoflavone intake and reduced mortality.

Researchers are already using single - cell analysis to identify genetic variations within tumors and tissues, and Langsdorff says the technique is quickly establishing a foothold in microbiology as well.

The study, «Lenalidomide (LEN) maintenance (MNTC) after high - dose melphalan and autologous stem cell transplant (ASCT) in multiple myeloma (MM): A meta - analysis (MA) of overall survival (OS),» is ASCO 2016 abstract no. 8001 and will be discussed during the Hematologic Malignancies — Plasma Cell Dyscrasia oral abstract session Friday, Juncell transplant (ASCT) in multiple myeloma (MM): A meta - analysis (MA) of overall survival (OS),» is ASCO 2016 abstract no. 8001 and will be discussed during the Hematologic Malignancies — Plasma Cell Dyscrasia oral abstract session Friday, JunCell Dyscrasia oral abstract session Friday, June 3.

The tool acts with surgical precision to replace only abundances that have most likely dropped out and can be used in any type of single - cell gene - expression analysis.

The finding, reported by a Stand Up to Cancer - Prostate Cancer Foundation Dream Team in the May 21 edition of the journal Cell, is based on an analysis of tumor samples from 150 men with metastatic prostate cancer that no longer responded to standard hormone - blocking therapy.

Two months after therapy, tissue analysis showed less scarring and higher levels of regenerative agents such as fibroblast growth factor — which accelerate healing — in rats treated with SIS plus stem cells compared with those treated with SIS alone.

Spearheaded by first author Christopher McNair, PhD, a graduate student in the laboratory of Dr. Knudsen, the study undertook an extensive analysis of tumor samples and cell - free DNA samples from patients with advanced, lethal - stage prostate cancer.

The analysis, reported online December 9 in Cell Host & Microbe, adds missing information about how the virus...

Using computational data analysis, Hughes hopes to create evolutionary trees of these genes and regulatory mechanisms in order to figure out how they work together to make cells function and how they contribute to the physiology of the organisms they are found in.

Further analysis of the genes that had been stimulated in the responders revealed that they were involved in immune cell function relevant to the inflammatory disease process in RA.