Sentences with phrase «cell and tissue regeneration»
Collagen is vital for the creation of healthy teeth and gums and aids in cell and tissue regeneration.
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Both medications help with cell and tissue regeneration, the building of muscles while reducing the formation of excess fat tissue.
Not exact matches
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The discovery is an important advance in the search for new medications to fight obesity, said senior investigator Shingo Kajimura, PhD, UCSF assistant professor of cell and tissue biology, with a joint appointment in the UCSF Diabetes Center and the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at Ucell and tissue biology, with a joint appointment in the UCSF Diabetes Center and the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCell Research at UCSF.
Get a cut on your finger and your skin can make new cells to heal the wound; lose your tail — if you are a particular kind of lizard — and tissue regeneration may produce a new one.
Moreover, the scientists have found that these stem cells depend upon a family of proteins known as the «Wnt signaling network» — the same proteins that play a crucial role in hair and tissue regeneration — to regenerate bone in the fingertip.
«Immune system found to control eye tissue renewal in zebrafish: Discovery suggests that strategies to regulate immune system cell reactivity to injury and cell loss might one day unlock and boost human tissue and cellular regeneration.»
A group of researchers led by Kosuke Fujita, Visiting Researcher and Akito Maeda, Specially Appointed Professor at the HP Skin Regeneration, PIAS Collaborative Research, Osaka University clarified that cinnamtannin B - 1, or vegetable - based polyphenol, promotes the migration of Mesenchymal Stem Cells (MSCs) in blood circulation and accumulates them in damaged tissues (Fig. 1) to improve wound healing.
Normally, in the absence of injury, the tissue can tolerate the loss, due to the presence of the active stem cells, but, when you injure the animal, the regeneration is compromised and the enhanced regeneration after calorie restriction was compromised in the absence of the reserve stem cell pool.»
This has allowed «true discovery science,» producing fundamental advances in «understanding the molecular control of regeneration and how cells communicate to rebuild injured tissues,» Carmichael adds.
«The worm was initially used as a model to study embryology and neurobiology, and starting in the late 1990s research expanded into stem cell biology, tissue homeostasis, and regeneration, topics that are still very actively studied today,» he says.
The transformed cells are transplanted onto plant regeneration medium, which contains nutrients and hormones that cause the tissue to grow into a tiny new plant.
«We expect that a patient's central nervous system cells could migrate into the implanted scaffold, adhere to it, grow and contribute to neural tissue regeneration,» he says.
Without Rac1, dead cells and milk flooded the breast when lactation had finished, triggering inflammation and impairing tissue regeneration (Developmental Cell, doi.org/bq8q).
I don't know too many other consortia which can integrate expertise in embryonic and tissue stem cell biology, tissue regeneration and repair, bioengineering and nanotechnology, materials science, genomics and bio-informatics.
Researchers used cultured stem cells derived from their feline patients in the hope of reducing inflammation and promoting tissue regeneration.
With the progression of heart regeneration, these cells were permanently installed in the muscle tissue and made their contribution to the restoration of cardiac function.
Cell regeneration is a biological feature of all living organisms with an important role in growth, wound healing, tissue repair and similar biological functions.
which is focused on mouse models of adult stem cell differentiation and tissue regeneration.
The researchers discovered that the activity of this electric signal is necessary in different aspects of normal regeneration, namely for the expression of crucial genes, formation of a mass of cells capable of growth and regenerate, and proper tissue innervation.
The Hippo pathway not only defines final tissue size by controlling developmental growth, but is also key to specifying stem cell identity and proliferation, to regeneration and tissue repair, as well as numerous cell fate decisions.
Normal maintenance and cell turnover throughout the planarian body continue unaffected when fst is inhibited, even though these activities rely on the same neoblast cell population that creates new tissue during regeneration.
Researchers at Whitehead Institute have uncovered a framework for regeneration that may explain and predict how stem cells in adult, regenerating tissue determine where to form replacement structures.
Recent advances in our basic knowledge of the pathways involved in tissue damage and regeneration have combined with remarkable progress in adult stem cell biology to put us at a genuine inflection point in the history of medicine.
He uses the paradigm of nuclear hormone receptor activation / signaling and the contribution of this process to myeloid cell differentiation, function, and to diseases, involving these cells, such as atherosclerosis, tissue regeneration, metabolic, and various inflammatory disorders, as his model systems.
His laboratory investigates how cell type specific differences in protein synthesis and homeostasis promote tissue regeneration and suppress the development of cancer.
The model organism offers a way to better understand stem cell - driven regeneration processes, an important step in regenerative medicine and the promise of therapies to repair or replace damaged human tissue.
Most of the scientific focus to date has been on trained on the blastema, a remarkable cluster of cells that forms at the base of an amputated limb or damaged tissue and is the modus operandi for regeneration.
Such insight will uncover the manner by which these cells exit from the quiescent state and become activated and drawn towards sites of inflammation and injury in order to trigger and enhance tissue regeneration.
«We have demonstrated that engineered blood vessels prepared with smooth muscle progenitor cells from hair follicles are capable of dilating and constricting, critical properties that make them ideal for engineering cardiovascular tissue regeneration,» said Andreadis.
They are also commonly referred to as «repair cells» for their ability to heal injured organs or body parts by accelerating tissue repair and regeneration, decreasing inflammation as well as increasing blood flow through the growth of new blood vessels.
In collaboration with experimentalists we use these methods to study self - organization phenomena of cell populations in tissue development, disease and regeneration.
Dr. Yamanaka's iPS discovery, first completed with animal cells in 2006 and with human cells in 2007, has since altered the fields of cell biology and stem cell research — opening promising new prospects for drug discovery, personalized medicine and tissue regeneration.
By stimulating the growth of new blood vessels, promoting anti-inflammatory effects, recruiting cells toward tissue regeneration and inhibiting further cell death, adult stem cells can restore some function to damaged or diseased heart muscle.
Our underlying premise is that the tumor microenvironment is immune suppressive because cancer cells elicit responses characteristic of wound healing and tissue regeneration.
Graber will also lead the development of the Comparative Models of Regeneration Database (RegenDB), a novel bioinformatics resource supported by the National Institutes of Health (NIH) whose function is to integrate gene function across multiple animal, tissue and cell models in order to validate and inform the hypotheses needed for the discovery and development of regenerative medicine drug therapies.
Cell therapies deliver stem / progenitor, primary and / or genetically modified cells, to facilitate regeneration of damaged cells within an organ / tissue.
«Humans have very limited capacity for regeneration, while other species like salamanders have the remarkable ability to functionally regenerate limbs, heart tissue and even the spinal cord after injury,» said lead researcher Karen Echeverri, PhD, assistant professor in the department of genetics, cell biology and development at the University of Minnesota.
Researchers demonstrate that autologous oral mucosal epithelial cells expanded under good manufacturing practice requirements can reverse limbal stem cell deficiency in injured eyes up to 24 months, representing an advance in ocular tissue regeneration and transplantation
In a new STEM CELLS Translational Medicine study, Zhang et al. now report that the overexpression of Platelet - Derived Growth Factor - BB (PDGF - BB), a well - known potent mitogenic, angiogenic, and chemoattractive agent, can significantly enhance dental tissue regeneration [5].
Studies of satellite cell activation via nitric oxide have opened an exciting area of research on muscle regeneration, growth and the muscle - fiber cytoskeleton that integrates mechanical and biochemical signal transduction with cell and molecular biology of muscle tissue in growth, development, disease, aging and evolution.
Ko IK, Ju YM, Chen T, et al., Combined systemic and local delivery of stem cell inducing / recruiting factors for in situ tissue regeneration.
«Cells are not passive,» said Valerie Weaver, the director of the Center for Bioengineering and Tissue Regeneration at the University of California, San Francisco.
The study supports the idea that patients with coronary artery disease may benefit from cardiac rehab programs, which drive the progenitor cells into the ischemic tissue, so they can contribute into vascular repair and regeneration.
Areas of research include biochemical and cellular mechanisms, muscle contractility and cell motility, the genetic control of cell growth and differentiation, and tissue damage and regeneration.
Moreover, the award will fund a tissue regeneration program that helps to identify biological factors that either contribute to or help prevent against damage that diabetes causes to the body's insulin - producing cells, eyes, kidneys and cardiovascular system.
The safety and efficacy of using embryonic and other stem cells for tissue regeneration will depend on harnessing and precisely controlling their proliferative capacity.
Developed by a multi-disciplinary team of Wyss Institute and Harvard SEAS faculty and researchers, the application of cylic mechanical stimulation of the injured tissue resulted in two - and - a-half-fold improvement in muscle regeneration, reduced tissue scarring and fibrosis, and a visible increase in the density of muscle cells.
Adult stem cells serve as a reservoir of cells for repair of damaged tissue throughout the life of an individual, but the maintenance and regeneration of tissues, such as skin, liver, blood and muscle, dramatically decrease with age.
RegenDbase — the Comparative Models of Regeneration Database — provides a systems - level view of genes across models of tissue regeneration to advance knowledge of regenerative biology and stem cell selRegeneration Database — provides a systems - level view of genes across models of tissue regeneration to advance knowledge of regenerative biology and stem cell selregeneration to advance knowledge of regenerative biology and stem cell self - renewal.