Sentences with phrase «cell assay development»
Phenotypic stability and unlimited self - renewal capacity of cell derived from pluripotent stem cells are essential properties for cell assay development for High Throughput Screening (HTS) strategies.
http://www.istem.eu/ Not exact matches
The scientists combined computer - based screening and cell - based assays to create a method that can significantly accelerate drug discovery and thereby lower development costs.
He has worked in the biotech industry as a research scientist for over 11 years with a focus on emerging technologies including gene targeting in mice, molecular analysis of transgenes using GFP variants at the single cell level, and developing flow cytometry reagent kits to speed up assay development time for researchers.
The Molecular Screening and Protein Expression Shared Resource fosters collaboration by providing expertise in biochemical and cell - based assay development for high - throughput screening and compound profiling.
We focus more specifically on: (A) GMP translations of CTP production and Quality Control assay development to evaluate such production (in collaboration with Roslin Cells, UK).
The findings from this one cell line are also inconsistent with clinical data from preimplantation genetic diagnosis, further suggesting that the stem cell assay may not wholly reflect what happens during human development.
Dr. Joyal has over 20 years of drug discovery experience with expertise in cell and molecular biology, particularly in the areas of receptor biology, cell signaling pathways, and assay development.
His laboratory (The Laboratory for Cell and Gene Medicine) specializes in the development of manufacturing processes and QC assays and provides cGMP compliant clinical materials production and regulatory support activities for investigational cell produCell and Gene Medicine) specializes in the development of manufacturing processes and QC assays and provides cGMP compliant clinical materials production and regulatory support activities for investigational cell producell products.
Contribute to the hands - on development and performance of immune - monitoring assays for patients receiving candidate cell therapies
«Having a reliable biomarker to assay the presence of senescent cells is very important step for accelerating both drug discovery and drug development programs.»
With continued growth in development and approval of biologic drugs and cell therapies comes a need for more robust and predictive cell - based assays.
This workshop focuses on considerations for development of a multiplexed immunoassays; examples of multiplexed assays for research release and other toxicities associated with CAR - T cells; and a novel flexible platform for biomarker screening and assessment of toxicities in samples exposed to CAR - T cells.
SAN DIEGO, March 28, 2017 (GLOBE NEWSWIRE)-- Invivoscribe ® Technologies Inc., a global company with decades of experience providing internationally standardized clonality and biomarker testing solutions for the fields of oncology, personalized molecular diagnostics ®, and personalized molecular medicine ®, reports that its next - generation sequencing (NGS) LymphoTrack ® Assay kits are being used by its LabPMM ® clinical laboratories, pharmaceutical partners, and cancer centers to identify and monitor chimeric antigen receptor T - cells (CAR - T) and engineered T - cell receptors in peripheral blood of subjects in support of immuno - therapeutic drug development and treatment regimen development for both hematologic and solid tumors.
For example, assaying the genomes of multiple cells during development reveals developmental lineage trees - the kinship lineage - whereas cellular transcriptomes inform us about the regulatory state of cells and their gradual restriction in potency - the Waddington lineage.
Development of a rapid cell - based assay for prions.
The development of a standardized method to express large panels of P. falciparum cell surface and secreted proteins in their native conformation would enable comprehensive protein libraries to be systematically screened in parallel so that direct comparisons between antigens can be made in functional assays such as vaccine screening and immuno - epidemiology studies.
Tags for this Online Resume: high throughput screening, cell culture, data, assay development, drug discovery, label - free, Biacore, Perkin Elmer, small molecule, hit - to - lead, ion channel, GPCR, enzyme, enzymatic, assay
Summary: Experienced cell / molecular biologist with background in bioanalytics, cell - based & ligand bind - ing assay development / validation, early discovery of therapeutic biologics and anticancer drugs.
Oversaw cell based assay development, Kinase receptor activation assay (KIRA), cell adhesion assays, reporter gene assays, cell bridging assays, and Cytotoxicity assays.
Microscopy Tissue Culture Multi-Color Flow Cytometry Assay Development High - Content Imaging Protein Expression & Purification Techniques Molecular Genetics Techniques Western Blot ELISA Immunofluorescence Microscopy Human Primary Cell Culture Data Analysis
Tags for this Online Resume: Business Development, CRO Services, Biologics, Small Molecules, Preclinical Drug Development, Drug Discovery, In Vivo efficacy models, Preclinical R&D, ELISA, Cardiovascular, Cellular, Injections, Oncology, Research, Pharmaceutical, Business Development Manager, Cancer, Applications, Automation, Field Applications Scientist, Cell based assays
Tags for this Online Resume: Research and Development, microbiology, molecular biology, biochemistry, protein purification, qPCR, X-ray crystallography, cryo - EM, homologous recombination, recombinant virus, mammalian cell transfection, virology, protease activity assay, TRITC fluorescence, fluorescence - based assay
I have an extensive background in analytical chemistry, biochemistry, toxicology, immunology / vaccine assay development, and highly experienced in protein characterization, enzymes, cell - based assays, fermentation processes, material characterization and impurity testing.
I specialize in the development of cell - based assays using genomic, proteomic and biochemical approaches implementin...