Sentences with phrase «cell behavior by»

In the adult central nervous system, the vasculature of the neurogenic niche regulates neural stem cell behavior by providing circulating and secreted factors.

Other researchers have tried changing cell behavior by creating protein switches from scratch, but Lim's approach — mixing and matching naturally existing proteins — may be more versatile and practical: «It can be useful as a biotechnology device or for repairing cells in humans.

Not exact matches

While we should hesitate to pass an anachronistic judgment on his behavior, we can at least restrain the celebrations of his fiancée, Maria von Wedemeyer, as his true love, the heroine for the perfect hero — celebrations that were inspired by the publication of their correspondence in Love Letters from Cell 92.

The findings, published by Cell Press in the March 8 issue of the journal Neuron, may help to explain why young children often struggle to control selfish impulses, even when they know better, and could impact educational strategies designed to promote successful social behavior.

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«The key point here is that we can say something about how the gene acts to influence this behavior — that is, is by functioning as a chemical messenger in cells that control this behavior in the brain.

By manipulating chemical reactions, behaviors of cells can be mimicked resulting in chemical factories on the nanoscale controlled and not by physical touch but by magnets and lighBy manipulating chemical reactions, behaviors of cells can be mimicked resulting in chemical factories on the nanoscale controlled and not by physical touch but by magnets and lighby physical touch but by magnets and lighby magnets and light.

The researchers observed the worms» behaviors through stages of maturity by recording the activity patterns of each cell in the circuit.

Next, Anderson and his colleagues used a set of genetic tools to identify exactly which neurons were responsible for the effect on aggression and to see if the gene that encodes for Tk also controls aggressive behavior by acting in that cell.

How can scientists be so easily fooled by the behavior of a cell?

Wall was the senior and corresponding author on a paper, titled «Cell Rejuvenation and Social Behaviors Promoted by LPS Exchange in Myxobacteria» that was published in the May 18 online issue of the Proceedings of the National Academy of Sciences (PNAS).

And it's essential to understand how neurobiological processing conducted by molecules and cells and electrical signaling gets translated into behaviors, from simple bodily movements to complex social interactions.

But according to Michael McKeown, a developmental geneticist at the Salk Institute in La Jolla, California, fru's presence in nine small clusters of fly nerve cells — including several previously mapped by Hall as «courtship centers» — may begin to give researchers «a handle on how the neural circuits that generate complex behaviors are put together.»

«This is the first study to show the actual cell behaviors caused by mutations in genes causally linked to polycystic kidney disease, an important new step in the path towards treatment,» said Dr. Robert L. Bacallao, associate professor of medicine at the IU School of Medicine in Indianapolis.

Results suggest that cells grown in the device exhibit more natural behaviors than when grown in traditional culturing methods, and the filtration by the glomerulus is necessary for healthy cell function.

The research suggests that reducing production of the protein, called myoferlin, affects cancer cells in two primary ways: by changing the activation of many genes involved in metastasis in favor of normal cell behavior, and by altering mechanical properties of cancer cells — including their shape and ability to invade — so they are more likely to remain nested together rather than breaking away to travel to other tissues.

Based on anatomy and molecular markers, we propose that it arose by duplication of a neighboring stem cell, which may have enabled finer neuronal control over leg - related behaviors, such as walking and grooming.»

Egg - laying behavior in Aplysia is mediated by a set of peptides, including egg - laying hormone (ELH), which are released by a cluster of identified neurons, the bag cells.

The activation dynamics of the transcription factor NF - κB exhibit damped oscillatory behavior when cells are stimulated by tumor necrosis factor — α (TNFα) but stable behavior when stimulated by lipopolysaccharide (LPS).

His research group focuses on big data network biology, exploring biological systems by developing and deploying algorithms aimed to predict cell behavior, in particular looking at cellular signal processing and decision making.

«This year's Nobel Laureates have been studying this fundamental problem and solved the mystery of how an inner clock in most of our cells in our bodies can anticipate daily fluctuations between night and day to optimize our behavior and physiology... since the paradigm shifting discoveries by Hall, Rosbash and Young, circadian biology has developed into a highly dynamic research field with vast implications for our health and well - being.»

Two different inherited genetic variations in two different families of children with ASD «converged» to produce the same changes in nerve function and behavior, the researchers report in EBioMedicine, a new online translational medicine journal published by editors at The Lancet and Cell Press.

A strategic focus is to continue to develop computational tools (such as KinomeXplorer, NetworKIN, and NetPhorest) and to deploy these on genome - scale quantitative data obtained by, for example, mass spectrometry, genomic, and phenotypic screens to understand the principles of how spatio and temporal assembly of mammalian signaling networks transmit and process information at a systems level in order to alter cell behavior.

«The nanoparticle mimics the behavior of NADPH oxidase, an enzyme used by immune cells to kill tumor cells and infectious agents.

They then tested the behavior of human tumor cells with and without HOXA5 by injecting those cells into the mammary fat pad of mice.

By themselves, leader cells do not need VEGF for invasive behavior, but VEGF appears to be important for pack formation because it is a mobility factor leaders provide followers.

The team, led by Stephen Liberles, Harvard Medical School associate professor of cell biology, has effectively deconstructed the vagus nerve, a key connection between body and brain that is important because it controls not only breathing but also heart rate, feeding behavior and responses to illness.

The study recently published in «Cell Stem Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavCell Stem Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavCell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavcell behavior.

The research team led by Prof. Fiona Doetsch at the Biozentrum of the University of Basel has now shown that the choroid plexus is a key component of the stem cell niche, whose properties change throughout life and affect stem cell behavior.

The team also demonstrated the utility of the platform by applying it to examine a growth - modulating feedback circuit whose dynamics is qualitatively altered by circuit - host couplings and revealing the behaviors of a toggle switch across scales from single - cell dynamics to population structure and to spatial ecology.

It likely works to prevent cancer by enhancing MAP1S - activated autophagy, or the cells» self - eating behavior: The benefits of spermidine disappear when MAP1S isn't available.

One way to do this is by manipulating dendritic cells, the coordinators of immune system behavior.

Specifically, dopamine provides reinforcement by enhancing the responsiveness of connections between cells so that a circuit can more easily repeat its rewarding behavior in the future.

In addressing the first question, the study showed that the brain's immune cells, microglia, which are known to become activated by LPS exposure as well as in most brain injuries and diseases, begin spewing out pro-inflammatory factors that change astrocytes» behavior.

The research team tested the hypothesis by transplanting cells onto the surface of mouse bone grafts and studying the cell behavior both in vivo — inside the animal — and in vitro — outside the body.

Now Prof. Daniel Offen and Dr. Adi Shruster of Tel Aviv University's Sackler School of Medicine have discovered that by reestablishing a population of new cells in the part of the brain associated with behavior, some symptoms of Alzheimer's disease significantly decreased or were reversed altogether.

«That way, information transmitted by this special dendrite influences the behavior of the nerve cell more than input from any other dendrite,» Kelly says.

The Purkinje cells, a class of neurons located in this region, are a major site of information integration that regulate changes in neural connections caused by varying factors such as behavior, environment, and emotions.

Dr. Christie's research team will further investigate the activity of Purkinje Cells in motor learning and the potential modifications in their activity caused by a perturbation on their behavior.

Animals learned to move their eyeballs once every second, a completely internal timing feat made possible by the rhythmic behavior of small groups of nerve cells, researchers propose online October 30 in PLOS Biology.

It may, for example, partly account for the differences in brain structure and behavior between identical twins, and could even affect thought processes by subtly influencing the changes in nerve cell connections that occur with experience.

Lee and his colleagues believe that NK cells help to regulate insulin resistance by releasing signaling proteins that affect the behavior of macrophages, another kind of immune cells.

The team led by Rory Fisher, Ph.D., professor of pharmacology in the UI Carver College of Medicine, has identified a protein called RGS6 (regulator of G protein signaling 6) that acts through two separate mechanisms to control alcohol - seeking behavior and alcohol - induced cell death in heart, liver, and other organs.

Previous work by Fredberg and colleagues had documented the importance of collective cellular behavior in asthma, showing that cells comprising epithelial tissues — which line the surfaces of all organs throughout the body — can unjam and flow like a fluid, or jam and freeze like a solid.

«Since cholesterol is required by neurons to form synapses (connections) with other cells, this decrease in cholesterol could affect how nerves function for appetite regulation, behavior, memory and even pain and motor activity,» says Dr. Kahn, who is also Mary K. Iacocca Professor of Medicine at Harvard Medical School.

For example, intra-strain cooperative behaviors are more likely to be evolutionarily stable when different cell lineages are segregated in space, with typical interaction distances between cells being strongly influenced by the diffusivity of secreted products, biofilm architecture, and environmental flow conditions [16 — 19].

The first genetically encoded optical tool that can precisely control brain cells (neurons) by the millisecond, optogenetics allows for light - induced control of neuronal activity, helping researchers understand how neurons form circuits that control behavior.

The information gathered by your senses is transmitted by nerve cells, or neurons, to specific brain regions where the signal is routed through circuits and sent downstream to areas that essentially translate the information into behavior and get you back on track.

Researchers from the Texas A&M University have discovered that a person's alcohol drinking behavior could be easily influenced by activating a certain set of nerve cells in the brain.

The channel - like property could have evolved, says Edwards, to meet the important need of moving large amounts of glutamate quickly, for while the other neurotransmitters are involved in modulating behaviors, such as mood, and therefore don't need to act with millisecond speed, glutamate functions by rapid - fire communication between closely placed nerve cells, and could require the fast action of the channel mechanism.