Sentences with phrase «cell biology approaches»

We discovered several Eph receptors and ephrins, and research in our laboratory is dedicated to the characterization of Eph receptor signal transduction mechanisms and biological functions using biochemical, mass spectrometry, molecular biology and cell biology approaches in conjunction with animal models.

Her laboratory has successfully combined electrophysiological expertise with molecular and cell biology approaches to better understand complex mechanisms underlying the memory process in mouse models of AD.

Not exact matches

Since the completion of the Human Genome Project in 2003, scientists have expanded their knowledge of how living cells work with new approaches including genomics, proteomics, and systems biology.

Earlier, for his Ph.D., he used his physics training to study biological interactions at the molecular resolution — but for his postdoc he changed approaches dramatically, turning to cell biology and applying his skills to the development of high - resolution functional imaging of DNA transcription in living cells.

Xian - Cheng Jiang, PhD, professor of cell biology at SUNY Downstate Medical Center, has led a study identifying a new approach for lowering «bad» lipids in blood circulation, a critical means to combat devastating cardiovascular diseases such as atherosclerosis.

These are at length / time scales intermediate between the CHEMICAL BIOLOGY AND BIOPHYSICS IRG and the MOLECULAR APPROACHES TO CELL FUNCTIONS AND INTERACTIONS IRG.

This general approach, known as lineage - tracing, has been a mainstay of classical developmental biology research and has greatly clarified knowledge of tissue stem cells during the last decade.

His laboratory uses a multidisciplinary approach encompassing systems biology, molecular pharmacology, biochemistry / proteomics, cell and structural biology, and computation / bioinformatics.

His current research uses a variety of molecular, biochemical, and genetic approaches to study the basic biology of mesenchymal stem cells (MSCs).

Dr Oliver Stegle, Group Leader at The European Bioinformatics Institute (EMBL - EBI) and co-lead scientist on this research, said: «Our method combines precise biological studies and complex computational approaches to integrate multiple aspects of cell biology.

His approach to the top of the tree (home to eukaryotes, which wrap their DNA in membrane - bound cell nuclei) would rule biology classrooms for decades.

In that time, image acquisition and analysis technologies have evolved to provide a wide range of optical approaches to high throughput analysis of cell biology processes in situ and in - context.

Using a combination of molecular biology, biochemical and novel multi-dimensional digital imaging approaches we study in real - time complex multi dimensional signal integration during the interaction of T cells with live antigen - presenting cells.

Dr. Ding has pioneered the development and application of innovative chemical approaches to stem cell biology and regeneration.

Our laboratory is interested in developing and applying innovative chemical approaches to stem cell biology and regeneration.

It uses cutting edge approaches to understand entire systems involved in complex biology, from a cell to the central nervous system.

In our interdisciplinary approach, we combine cell and molecular biology, molecular genetics, biophysical tools including laser microsurgery, optical engineering, computer science and theoretical physics.

The broad area of molecular, cell and developmental biology is a rapidly growing area that has deeply impacted modern biological approaches.

It also supports our belief that in the future, one might be able to use this approach for replacement of cells lost or malfunctioning due to other more common diseases of the retina,» said lead study author cell biologist Jason Meyer, Ph.D., assistant professor of biology in the School of Science at Indiana University - Purdue University Indianapolis.

The workshop intended to serve as a tutorial about mathematical and bioinformatics approaches in current stem cell biology.

Colleagues speak of his enthusiasm and rich interdisciplinary approach spanning not only chemistry and microscopy, but neuro -, cell, and cancer biology as well.

Glass and his Venter Institute colleagues are now using synthetic biology and synthetic genomics approaches developed at the JCVI to create cells and organelles with redesigned genomes to make microbes that can produce biofuels, pharmaceuticals, and industrially valuable molecules.

Chory and her team run a vertically integrated program, using genetics, genomics, cell biology, x-ray crystallography, biochemistry and ecological approaches.

The workshop is organized by Ingo Roeder and Ingmar Glauche, Institute for Medical Informatics and Biometry and it is intended as a tutorial about mathematical and bioinformatics approaches in current stem cell biology.

We use a combination of approaches from organic chemistry, biochemistry and cell biology to ensure the capability to address a given problem from as many angles as possible.

Even though it wasn't planned this way, says Atkinson, the three «Tell Your Own Cell Story» videos demonstrate three different approaches to the challenge of making cell biology visible to the woCell Story» videos demonstrate three different approaches to the challenge of making cell biology visible to the wocell biology visible to the world.

The Cosford lab employs medicinal chemistry and chemical biology approaches to probe cellular pathways that regulate cell survival pathways in deadly tumors.

His research interests belong to pushing frontiers of microscopy for cell biology, developing of new microscopical tools, systems and approaches.

For this we use gene replacement, live and fixed cell imaging, conditional localization and (in) activation approaches, proteomics, biochemistry and structural biology.

His lab has engaged in a multidisciplinary approach, simultaneously exploring the basic biology of stem cells, their role throughout the lifetime of an individual, as well as their therapeutic potential.

Dissecting these interactions with a combination of cell - biology and systems biology approaches should allow uncovering the tissue specific control mechanisms that are defective in cancer.

The National Institutes of Health has awarded Virginia Tech researchers a $ 2.13 million grant to develop new systems biology approaches to study cells, one of the most basic units of life.

We use various approaches including genetics, genomics and cell biology to study gene functions in normal development and disease such as cancer.

Technology Integrates stem cells from patients into a new approach to predict most effective disease treatments based on a patient's unique biology.

Objective: To use innovative approaches of integrative biology to unravel how lymphocytes process an array of molecular signals arising from contact with dendritic cells, thereby better understanding the mechanisms that underlie immunity and how they are altered in disease states.

Students receive training with a «systems» biology approach through courses, bench work, lab discussions and publications spanning a broad range of muscle - biology questions using studies at the level of single cells, tissues, animals and humans.

This symposium will cover cell and developmental biology, tissue biophysics, theoretical modelling, organoids and synthetic biology, and provide a platform to discuss and identify key approaches and future collaborations in tissue self - organisation.

The lab investigates consequences of epigenetic alterations in neuronal cancers and neurodegenerative diseases using a combination of biochemistry, cell and molecular biology with genome wide approaches to gain mechanistic insight into how chromatin architecture is modified in disease.

Expertise in at least one of the following areas is desired: bone biology, stem cell biology, mouse models, and high - throughput sequencing approaches for RNA and chromatin.

The Innovator Award will enable Sipkins to continue to combine state - of - the - art imaging techniques, performed on living mice, with cell and molecular biology approaches to learn more about these stem cell niches.

We discuss the recent advances to address the question and characterize the developmental constraint in evolution, by integrating approaches from cell, and evolutionary biology, bioinformatics, and theoretical biophysics, and provide the future perspective in the quantitative evo - devo studies.

The goal of our conference is to disseminate recent findings emerging from cell biology, biochemistry, biophysics, functional - genomics, systems and computational approaches; and integrate them into a mechanistic understanding of the global principles of cell division.

The Van Oudenaarden group uses a combination of experimental, computational, and theoretical approaches to quantitatively understand decision ‐ making in single cells, with a focus on questions in developmental and stem cell biology.

It uses cutting - edge approaches to understand entire systems involved in complex biology, from a cell to the central nervous system.

«The development of a functional human kidney glomerulus chip opens up an entirely new experimental path to investigate kidney biology, carry out highly personalized modeling of kidney diseases and drug toxicities, and the stem cell - derived kidney podocytes we developed could even offer a new injectable cell therapy approach for regenerative medicine in patients with life - threatening glomerulopathies in the future,» said Ingber.

We use a combination of conditional mouse models, primary cell culture (human and mouse), live microscopy, highthroughput genomics and proteomics approaches, and basic molecular biology.

• Personalized drug safety can be addressed with patient - derived cells in Organ - Chips, enabling a patient - specific approach for assessing the safety and efficacy of new candidates while taking into account patient variability and the unique biology of individual patients.

The opportunity to closely interact with colleagues from different fields will generate an integrative perspective that unites diverse scientific approaches to microtubule research, ranging from structural biology, biochemistry, and biophysics to cell biology and organismal biology.

New data and research approaches have created opportunities for researchers to study in detail many aspects of cancer biology, including how the normal biological programs of cell proliferation and death are altered during cancer and how the immune system responds to tumors.

We challenge the mutual interdependence of lipid - protein interactions by an interdisciplinary approach, combining cell biology and synthetic biology as well as protein biochemistry, structure biology and biophysics.