Sentences with phrase «cell cancer appears»

Sometimes chemotherapeutic drugs are used in combination with prednisone if the mast cell cancer appears to have metastasized.

Not exact matches

The race to become the first company with a chimeric antigen receptor T - cell (CAR - T) cancer therapy on the market has entered its final leg, and Kite Pharma now appears to have a big advantage.

April 16 Merck & Co's immunotherapy Keytruda plus chemotherapy significantly improved overall survival versus chemotherapy alone in newly - diagnosed patients with advanced non-small cell lung cancer in a highly - anticipated study that appears to cement the company's lead in the most lucrative oncology market.

Persin, a natural toxin found in avocados, appears so effective at killing breast cancer cells that it is being considered as a chemotherapy agent.

Factors secreted by the locations containing non-pigmented melanocytes, such as melanocyte stem cells, appear to be able to suppress early cancer development.

But T - cells appear to be even more promising, because they can react to abnormalities inside cancer cells rather than just on their surfaces.

This article appears in print under the headline «Zika virus can be used to attack brain cancer cells»

Pembrolizumab, or pembro, an immunotherapy drug that unmasks cancer cells and allows the body's own immune system to help destroy tumors, appears to be safe in treating lung cancers, according to a study by Cancer Treatment Centers of America ® (CTCA) at Western Regional Medical Center (Western) in Goodyear, Arcancer cells and allows the body's own immune system to help destroy tumors, appears to be safe in treating lung cancers, according to a study by Cancer Treatment Centers of America ® (CTCA) at Western Regional Medical Center (Western) in Goodyear, ArCancer Treatment Centers of America ® (CTCA) at Western Regional Medical Center (Western) in Goodyear, Arizona.

In 1998, for example, Wiman's team screened a library of 2000 compounds from the U.S. National Cancer Institute and found two that appeared to restore mutant p53's ability to kill cancer Cancer Institute and found two that appeared to restore mutant p53's ability to kill cancer cancer cells.

«But it appears when mature cells return back into a rapidly dividing stem cell state, this creates problems that can lead to cancer.»

The drug that they have developed appears to target cancer stem cell activity, which suggests it will prevent metastatic recurrence and be useful in combatting drug resistance.»

The findings are the latest from the St. Jude Children's Research Hospital — Washington University Pediatric Cancer Genome Project and appear in the December 9 edition of the scientific journal Cancer Cell.

Now a team led by Robin Weiss of London's Institute of Cancer Research reports that the «PK» porcine endogenous retrovirus, which does not appear to harm pigs, can replicate in mink and human cells.

Epigenetic therapies are thought to work in two ways to fix these errors in cancer cells — by correcting the «position» of the gene switches and by making the cell appear as though it's infected by a virus, triggering the immune system.

Then the researchers turned to the lab, where they exposed human liver, breast, colon, ovarian, and other cancer cells to the drugs, which appeared to make it easier for the cells to migrate.

Circulating tumor cell (CTC) clusters — clumps of from 2 to 50 tumor cells that break off a primary tumor and are carried through the bloodstream — appear to be much more likely to cause metastasis than are single CTCs, according to a study from investigators at the Massachusetts General Hospital (MGH) Cancer Center.

These pathways appeared to be dialed down in the cancer cells, allowing for evasion.

Living in overcrowded conditions appears to protect children and young adults against developing a particular type of Hodgkin lymphoma (HL), a cancer that originates from the lymphocytes (white blood cells).

In studies of mice injected with human cancer cells, the drug appeared to work according to plan.

Cancer stem cells can be considered the most dangerous type of cancer cells, as they appear to have an inherent resistance to the chemotherapeutic drugs used Cancer stem cells can be considered the most dangerous type of cancer cells, as they appear to have an inherent resistance to the chemotherapeutic drugs used cancer cells, as they appear to have an inherent resistance to the chemotherapeutic drugs used today.

Lee's study results, which appear in the July 16, 2015 issue of Nature Communications, revealed new understanding about how 14 -3-3 sigma — a cell cycle «controller» - regulates cancer metabolic programming, thus protecting healthy cells from turning into tumor - producing factories.

UJ3 appears to target the mitochondria, resulting in programmed cell death to kill cancer cells — a process called apoptosis.

The resulting «map» of gene - drug interactions allowed the researchers to accurately predict the responses of multiple human cancer cell lines to different chemotherapy agents based on the cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of breast and ovarian tumor cells to common classes of chemotherapy treatment.

It appeared to bring the migration of the cancer cells to a halt.

They found that cancer stem cells seemed to appear in the highest numbers along the edges of the engineered tumor environments, particularly where there were corners and convex curves.

An experimental drug that targets abnormally high levels of a protein linked to cancer growth appears to significantly reduce the proliferation of prostate cancer cells in laboratory cell cultures and animals, while also making these cells considerably more vulnerable to radiation, according to results of a study led by Johns Hopkins scientists.

BMH - 21 also appears to overcome the tendency of cancer cells to resist chemotherapeutic agents because it finds and targets proteins and shuts down the communication pathways that cells use to continue dividing.

In the new study, the researchers cultured mouse skin - cancer colonies on various 2 - D and 3 - D environments of different shapes and patterns to see if the tumor shape contributes to activation of cancer stem cells, and to see where in the tumor the stem cells appeared.

The Nature Communications paper covers lung cancer cells; a similar phenomenon of collective invasion led by distinctive cells has been observed in breast cancer, but different genes and biochemical pathways appear to be important in each system.

«Cells appearing normal may actually be harbingers of lung cancer.»

But the cells didn't appear to be human, they were 10 times smaller than human cancer cells.

Their recent study, which appears as the cover article in the May issue of Cancer Research, shows that mathematical models can be used to predict how different tumor cell populations interact with each other and respond to a changing environment.

«New research helps explain why a deadly blood cancer often affects children with malaria: Immune responses to malaria - infected red blood cells appear to sometimes lead to cancer - promoting changes.»

In all instances, treatments involving the antibody — whether alone or in combination with chemotherapy — appeared to eradicate more cancer cells compared to standard care.

Sessler and colleagues at Pharmacyclics in Sunnyvale, California, found that cancer cells appeared as bright white regions on MRI scans even several days after a texaphyrin injection.

The study appears November 23 in Cancer Cell.

While this current study primarily focused on the role of Myc and TXNIP in triple negative cancer nutrient uptake and utilization, Ayer said the proteins also appear to play a role in metastasis, the process by which cancer cells spread to other parts of the body.

In a study appearing in Science Translational Medicine, the researchers report they have effectively and safely employed this stem cell - targeting system in mice to treat metastatic breast cancer that had spread to the lung.

When cancer cells proliferate, they appear to need the help of a protein called survivin: The protein is abundant in cancer cells but almost absent from normal cells.

In a paper appearing in the journal ChemBioChem, Pentelute and colleagues showed that they could use this disarmed version of the anthrax toxin to deliver two proteins known as antibody mimics, which can kill cancer cells by disrupting specific proteins inside the cells.

«Most other tumors have a mutant p53, but in these testicular cell tumors, the p53 is functioning properly, and the drugs used for testicular cancer appear to work in concert with p53's tumor suppression function to kill the cancer cells.»

Scientists have known that LPA is secreted by many types of cancer cells, appears to promote the growth and spread of tumor cells, and that immune cells known as CD - 8 «killer» T cells have several receptors for LPA.

According to the researchers, these findings suggest that differences in shape from cell - to - cell within a tissue are key to their ability to jam and unjam — and that this process appears to drive biological events including embryonic development, wound healing, and, potentially, cancer cell invasion.

Viewed through the glasses, cancer cells appear to glow blue under a special light, thanks to a fluorescent marker injected in the tumor that attaches only to cancerous and not to healthy cells.

By suppressing genes that are active in the developing embryo, silenced just before birth, and re-activated years later in many advanced cancers, the let - 7 family of «microRNAs» — tiny snippets of RNA that can put the brakes on expression of selected genes — appears to prevent human cancer cells from reasserting their prenatal capacity to divide rapidly, travel and spread.

Again, prostaglandins are important because they appear to promote cancer by activating pathways that control cell growth and movement.

First, cancer stem cells have appeared to be a huge trend, even hype within cancer research throughout the last one and a half decades, but the hope set into them stands on a solid experimental basis and is thus justified.

A full accounting of what is going on under the hood still remains to be accomplished, but the most plausible mechanism appears to be increased stem cell activity, while effects on cancer may involve a more active immune system - though that is only speculative theory at this point.

The findings may even have implications for studying glioblastoma, a common brain cancer whose ability to grow, migrate and hack into the brain's blood supply appears to rely on a pattern of gene activity similar to that now identified in these neural stem cells.

Part of that is because cancer cells in solid tumors appear to have learned how to «hide» better.