Not exact matches
During the sessions, U.S. and Cuban scientists explored such topics as the molecular mechanisms
cancer cells employ to evade the body's immune system, new tools to image and manipulate that system, and ways to rethink how such therapies can best be deployed to reach patients where they receive health services.
Vaccines depend on them, and scientists are even
employing the
cells to stir up immunity against
cancer
We
employ similar pathways to shape our parts as embryos, but over the course of evolution, humans may have lost the ability to tap into it as adults, perhaps because the
cell division required for regeneration elevated the likelihood of
cancer.
Just as youthful stem
cells use telomerase to offset telomere length loss,
cancer cells employ telomerase to maintain their aberrant and destructive growth.
The breakthrough technology uses a simple mechanical method that has been shown to be more effective in trapping
cancer cells than the microfluidic approach
employed in many existing devices.
The therapeutic
cancer vaccine
employs nanodiscs loaded with tumor neoantigens, which are unique mutations found in tumor
cells.
The single -
cell - analysis approach could likely be
employed to develop personalized treatment for many other types of
cancer as well.
In a study appearing in Science Translational Medicine, the researchers report they have effectively and safely
employed this stem
cell - targeting system in mice to treat metastatic breast
cancer that had spread to the lung.
He
employs mouse models to facilitate in - vivo lineage tracing from candidate stem
cell populations and to assess their contribution to
cancer initiation and progression.
For this compilation, I've emphasized publications in which whole - genome or exome sequencing was
employed to multiple tumors or
cancer cell lines, with the goal of identifying significantly altered genes or pathways in malignant
cells.
Our AST - VAC immunotherapy programs
employ three common elements of dendritic
cells, telomerase antigen, and the LAMP signal sequence to stimulate robust and specific immune responses to
cancer cells (Figure 1).
The present study
employed computer simulations to screen 300,000 fragments using an atomic resolution structure of the
cancer target MTH1, an enzyme part of the DNA - repair machinery of the
cell.
The team will identify genetic and epigenetic features in CAR T
cells and / or
cancer cells that will help predict which patients will respond to the immunotherapy, with an eventual goal of initiating clinical trials that
employ a combination of approaches to therapy.
SEngine
employs high - throughput screening to test selected drugs and drug combinations on
cancer cells extracted from your tumor.
For example, Penn's blood
cancer trials
employ a CAR targeting the protein CD19, which is found on the surface of B
cells, including the cancerous B
cells that characterize several types of leukemia and lymphoma.