Project Title: Identification of molecular alterations associated with the progression of clear cell renal
cell carcinoma by mass spectrometric approaches
Not exact matches
Renal
cell carcinoma, also known
by the eponym Grawitz tumor, is the most common form of kidney cancer arising from the renal tubule.
Lambert - Eaton syndrome, an autoimmune disorder frequently associated with small -
cell carcinoma of the lung, is characterized
by impaired evoked release of acetylcholine from the motor nerve terminal.
The prevalence of itch was greatest in squamous
cell carcinoma (46.6 percent), followed
by basal
cell carcinoma (31.9 percent) and melanoma (14.8 percent).
The researchers began
by identifying the genes that often mutate in human renal
cell carcinomas.
A phase I clinical trial conducted
by investigators at the University of Texas San Antonio, showed that the combination of HCQ and the chemotherapy drug vorinostat in 27 patients with advanced solid tumors, including renal
cell carcinoma and colon cancer, was clinically safe and inhibited autophagy.
Fragile skin that blisters easily: 90 percent of the patients that suffer from the skin condition recessive dystrophic epidermolysis bullosa (RDEB) develop rapidly progressing cutaneous squamous
cell carcinomas, a type of skin cancer,
by the age of 55.
Dr. Steven R. Goodman, Editor - in - Chief of Experimental Biology and Medicine, said «This study
by Huanbiao Mo and colleagues at the Texas Woman's University and UT Southwestern Medical Center demonstrates that geranylgeraniol causes dose dependent apoptotic death of human prostate
carcinoma cells.
Dr. Islam's discovery was published [S. Islam, T. E. Carey, G. T. Wolf, M. J. Wheelock, and K. J. Johnson, «Expression of N - Cadherin
by human squamous
carcinoma cells induces a scattered fibroblastic phenotype with disrupted
cell - cell adhesion,» J. Cell B
cell -
cell adhesion,» J. Cell B
cell adhesion,» J.
Cell B
Cell Biol.
New results from a clinical trial involving more than 900 military veterans at high risk for keratinocyte
carcinoma skin cancer provides evidence that using the generic skin cream fluorouacil 5 percent for two to four weeks may reduce the risk of a squamous
cell carcinoma (SCC) needing surgery
by 75 percent within a year.
However, a type of cellular signaling caused
by the BRAF inhibitors may leave patients susceptible to secondary malignancies, such as squamous
cell carcinoma and RAS - mutant leukemia.
Surprisingly, they found that although the patterns of gene expression — as shown
by the RNA sequencing — differed between the hepatocellular
carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall pattern of mutations in the
cells was actually similar between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were different in patients without such infections.
About three - fourths of renal
cell carcinoma cases are marked
by a missing VHL tumor - suppressor gene, which keeps healthy
cells from developing into tumors.
A higher intake
by postmenopausal women of the natural antioxidant lycopene, found in foods like tomatoes, watermelon and papaya, may lower the risk of renal
cell carcinoma, a type of kidney cancer.
The class of compounds that includes GDC - 0449 could also help contain other cancers, such as ovarian and colorectal cancers, that are not triggered in the same way as medulloblastoma or basal
cell carcinoma but that are still partly driven
by aberrant Hedgehog signaling.
Changes in
cell junctions induced
by inhibition of epidermal growth factor receptor in oral squamous
cell carcinoma cells.
The characteristic aggregation of lipid - containing structures around the embryonic nuclei clearly detected in C. elegans embryos
by CARS microscopy are reminiscent of lipid droplets recently reported to be a characteristic feature of cancer stem
cells in colorectal
carcinomas (Tirinato et al., 2015).
With Merkel
cell carcinoma, which almost always kills quickly, many more cases are triggered
by a common virus than
by exposure to ultraviolet light.
Identification of a human papillomavirus - associated oncogenic miRNA panel in human oropharyngeal squamous
cell carcinoma validated
by bioinformatics analysis of the Cancer Genome Atlas.
Zoledronic acid reverses cisplatin resistance in nasopharyngeal
carcinoma cells by activating the mitochondrial apoptotic pathway.
MiR - 514a - 3p inhibits
cell proliferation and epithelial - mesenchymal transition
by targeting EGFR in clear
cell renal
cell carcinoma.
Some of the tumors were less than 300 microns in diameter (a single red blood
cell,
by comparison, is about 7 microns across), and the new MRI also detected ductal
carcinoma in situ (DCIS), a precursor to invasive cancer.
Inhibition of epithelial to mesenchymal transition in metastatic breast
carcinoma cells by c - Src suppression.
The Lewis lung
carcinoma cell line was obtained
by ATCC (CRL - 1642 ™).
At age 62, Tom Jackson was diagnosed with squamous
cell carcinoma of the tonsil caused
by the human papillomavirus (HPV).
Institute researchers have learned that basal
cell carcinoma, the most common human cancer, is caused
by a defect in a gene that restrains
cell growth.
In an effort to further exploit the potential of Pexa - Vec to activate the immune system to fight cancer, as seen in McDonald's preclinical data, SillaJen recently announced a new clinical trial in collaboration with New York - based Regeneron Inc. to test Pexa - Vec and REGN2810, a PD - 1 checkpoint inhibitor, in combination against renal
cell carcinoma, and recently signed a sponsored research agreement with UCSF to enable joint support of parallel preclinical experiments
by McDonald's team.
The new study published in Cancer
Cell by Sarris et al. shows that Smyd3 expression correlates with poor prognosis of human hepatocellular
carcinoma.
This year brought a series of milestones in immunotherapy for Merkel
cell carcinoma — a rare and deadly skin cancer —
by Drs. Paul Nghiem, Kelly Paulson and colleagues:
RIG - G gene expression can be induced not only
by ATRA along with the differentiation of NB4
cells but also
by IFNα in a series of hematopoietic
cell lines as well as various types of solid
carcinoma cells (1, 3), which pointed to a possible role of RIG - G in signal cross-talk between ATRA and IFNα.
Activation of p53 in cervical
carcinoma cells by small molecules.
TGFβ inhibits tumor initiation and progression
by inducing
cell cycle arrest and apoptosis; however epithelial tumorigenesis may escape this common antitumor mechanism
by inducing aberrations in TGFβ signaling resulting in enhanced development and progression of human
carcinomas.
that specifically inhibit tumor growth
by targeting the Hedgehog pathway have been approved
by the FDA to treat basal
cell carcinoma, giving patients with advanced cases of this type of skin cancer a better chance of survival.
Suppression of Growth
by All - trans Retinoic Acid Requires Prolonged Induction of Interferon Regulatory Factor 1 in Cervical Squamous
Carcinoma (SiHa)
Cells
Since 2012, two drugs that specifically inhibit tumor growth
by targeting the Hedgehog pathway have been approved
by the FDA to treat basal
cell carcinoma, giving patients with advanced cases of this type of skin cancer a better chance of survival.
Nomograms Developed and Validated for Patients with Squamous
Cell Carcinoma of Larynx
by NRG Oncology Read more
It's prescribed to treat a type of skin cancer called superficial basal
cell carcinoma, and precancerous skin lesions caused
by sun exposure, called actinic keratosis.
That something was a basal
cell carcinoma, the most common and least dangerous skin cancer, usually caused
by sun exposure.
Curcumin inhibits interleukin 8 production and enhances interleukin 8 receptor expression on the
cell surface: impact on human pancreatic
carcinoma cell growth
by autocrine regulation.
A study carried out
by the department of Dermatology, University of California in June of 2011 involving 830 people comparing various vitamins found that the group taking grape seed extract experience a 74 percent reduction in squamous
cell carcinoma — a type of skin cancer.
Squamous
cell carcinoma in cat is usually caused
by the sun reaching exposed areas of your cat's body.
Unfortunately transitional
cell carcinomas usually have become quite large
by the time they are diagnosed, and with conventional treatments
by themselves, the prognosis is only a few months.
There are a variety of different treatments for squamous
cell carcinomas some of which can be performed
by your regular veterinarian and others which require a board certified equine ophthalmologist.
Squamous
cell carcinoma can be diagnosed in its earliest stages
by a biopsy of the lesion, which can be performed
by your veterinarian or veterinary ophthalmologist.
Cats are most commonly diagnosed with squamous
cell carcinomas followed
by fibrosarcomas.
A beta
cell carcinoma of the pancreas with metastasis to the liver and a mesenteric lymph node was confirmed
by surgery and histopathology.
Basal
cell and Squamous
cell Carcinoma are
by far the most common types of skin cancer.