Sentences with phrase «cell carcinoma cell lines»

Not exact matches

To address this question, the research teams from Berlin and Würzburg took a closer look at human colon carcinoma cell lines that innately show high levels of c - MYC.

The FDA granted accelerated approval to avelumab (Bavencio, EMD Serono, Inc.), a checkpoint immunotherapy that targets the PD - 1 pathway, as a first - line treatment for a rare form of skin cancer called Merkel cell carcinoma (MCC).

Bertram JS, Janik P. Establishment of a cloned line of Lewis Lung Carcinoma cells adapted to cell culture.

Medical oncologist Alexander T. Pearson, MD, PhD cares for adults with head and neck cancers, especially squamous cell carcinoma, a common form of cancer that develops in the squamous cells that make up the middle and outer layer lining the mouth and throat.

The Lewis lung carcinoma cell line was obtained by ATCC (CRL - 1642 ™).

Treatment of the Gb3 - expressing gastric carcinoma cell line St3051 with STxB coupled to SN38, the active metabolite of the topoisomerase type I inhibitor irinotecan, resulted in > 100-fold increased cytotoxicity, as compared with irinotecan alone.

About 9 out of every 10 kidney cancers are renal cell carcinomas — cancers that form in the lining of the tubules inside the kidney.

Flavopiridol inhibits several cellular kinases and has demonstrated cytostatic and cytotoxic activity in vitro and in vivo in numerous human tumor cell lines and xenograft models (including human breast, prostate, and lung carcinoma) at clinically achievable concentrations.

RIG - G gene expression can be induced not only by ATRA along with the differentiation of NB4 cells but also by IFNα in a series of hematopoietic cell lines as well as various types of solid carcinoma cells (1, 3), which pointed to a possible role of RIG - G in signal cross-talk between ATRA and IFNα.

To assess the ability of F3 - IgG to inhibit the proliferation of HER2 - overexpressing breast carcinoma cells, we measured the proliferation of BT474, MCF7 / HER2 and MCF7 breast cancer cell lines in the presence of trastuzumab, F3 - IgG, or an isotype - matched control antibody.

It is possible that the Oct4 expression patterns that we observe is due to failure of one or more of these processes in the complex, abnormal milieu of this embryonal carcinoma cell line during differentiation.

This was found to cause lysis in hepatocellular carcinoma cell lines, but not in normal liver cells indicating that further experimental studies on SOCS3 could increase its future applicability as a cancer cell specific anti-cancer agent.59

For example, women with stage 0 breast cancer may have ductal carcinoma in situ or DCIS, in which abnormal cells have developed in the lining of a breast duct.

Research reveals that both in cell lines as well as mouse models, grape seed extract kills neck and head squamous cell carcinoma cells, though keeping healthy cells unharmed.

The second is renal cell carcinoma, which affects the lining of the tiny tubes that filter blood.

In another study, 11 human cancer cell lines (carcinomas and glioblastomas) were exposed to ascorbic acid in which 55 % of the cell lines were more susceptible (EC50 ≤ 20 mmol / L) and 45 % were more resistant (EC50 > 20 mmol / L) to incubation.

The curcumin metabolite tetrahydrocurcumin decreases the activity of the phase III transporters in human cervical carcinoma and breast cancer cell lines.

A similar study published earlier in the journal Carcinogenesis found that in both cell lines and mouse models, grape seed extract killed head and neck squamous cell carcinoma cells, without harming nearby healthy cells.

Originating from epithelial cells (skin cells that cover the lining of body surfaces), Carcinomas can occur on the skin, bladder wall, and blood vessels that then pass into the surrounding tissues and organs.

Squamous cell carcinomas are malignant cancers originating from the lining cells of the mouth.

Cancers can be divided into three general groups: carcinomas that arise from epithelial cells that cover the body (skin) or line internal body surfaces; sarcomas that begin in connective, skeletal, muscular, or reproductive tissues; lymphomas that invade the lymph nodes and the lymphatic system.

Overall, study participants in the top 20 percent for red - meat intake were 79 percent more likely than those in the bottom 20 percent to develop esophageal squamous cell carcinoma — a cancer that arises in the lining of the upper part of the esophagus.