Human head and neck
squamous cell carcinoma cells transfected with mutant TP53 (SAS / mp53) or with neo vector (SAS / neo) were injected subcutaneously into hind legs of nude mice.
The human esophageal squamous
cell carcinoma cell lines KYSE 510 and KYSE 150 were gifts from Dr. Yutaka Shimada (Kyoto University, Kyoto, Japan).
Changes in cell junctions induced by inhibition of epidermal growth factor receptor in oral squamous
cell carcinoma cells.
Research reveals that both in cell lines as well as mouse models, grape seed extract kills neck and head squamous
cell carcinoma cells, though keeping healthy cells unharmed.
A study published in the journal Carcinogenesis shows that in mouse studies, grape seed extract kills head and neck squamous
cell carcinoma cells, leaving the healthy cells unharmed.
In a study published in Carcinogenesis, researchers found that grape seed extract killed squamous
cell carcinoma cells, while not harming nearby healthy cells.
A similar study published earlier in the journal Carcinogenesis found that in both cell lines and mouse models, grape seed extract killed head and neck squamous
cell carcinoma cells, without harming nearby healthy cells.