Sentences with phrase «cell carcinoma model»
Inecalcitol, an analog of 1,25 D 3, displays enhanced antitumor activity through the induction of apoptosis in a squamous cell carcinoma model system.
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Despite decades of effort, however, researchers were unable to develop a mouse model of renal cell carcinoma — until now.
Sanford Research scientists are published in Nature Cell Biology for their work developing a model to explore therapies for a pediatric brain tumor known as choroid plexus carcinoma.
The article, titled «Entinostat Neutralizes Myeloid Derived Suppressor Cells and Enhances the Antitumor Effect of PD - 1 Inhibition in Murine Models of Lung and Renal Cell Carcinoma,» was published in Clinical Cancer Research and is available online.
«Preclinical results support entinostat's role in targeting the tumor microenvironment: Entinostat inhibits function of myeloid derived suppressor cells resulting in enhanced antitumor effect in murine models of lung and renal cell carcinoma.»
Interleukin - 8 as a modulator of response to bevacizumab in preclinical models of head and neck squamous cell carcinoma.
Flavopiridol inhibits several cellular kinases and has demonstrated cytostatic and cytotoxic activity in vitro and in vivo in numerous human tumor cell lines and xenograft models (including human breast, prostate, and lung carcinoma) at clinically achievable concentrations.
Research reveals that both in cell lines as well as mouse models, grape seed extract kills neck and head squamous cell carcinoma cells, though keeping healthy cells unharmed.
A similar study published earlier in the journal Carcinogenesis found that in both cell lines and mouse models, grape seed extract killed head and neck squamous cell carcinoma cells, without harming nearby healthy cells.