An abnormal Pap test result means that there are abnormal
cell changes on your cervix.
Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required
on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize
cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to
changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact
on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Also, they have chosen a cheap populist theme, attacking
cell phone, bank and credit - card charges instead of hammering the Conservatives
on their dangerous, right - wing deregulation agenda — even though people are still dying as a result of Harper's «self - regulation»
changes to food safety.
This provides a game
changing advantage in regenerative medicine that otherwise relied
on the concept of stem
cells.
A source familiar with the matter said the
cell tower addresses were being sent to Google after a
change in early 2017 to the Firebase Cloud Messaging service, which is owned by Google and runs
on Android phones by default.
As a cancer researcher, do you think the mechanisms of tumor growth are somehow
changing to come into line with your perceptions, or is it possible that the process of our learning more about DNA mutations and
cell architecture and nutrient exchange and epigenetic effects make it possible for us to inch ever closer to understanding that which is already going
on under our noses?
... yeah suzy and others... I just happen to realize that when monkey devolving didn't quite work out
on paper it all
changed to single
cells and from the slime off of the worlds garbage can and so
on... I just happen to know more than you think... In another ten or twenty years the science books will all have a new teaching... the Bible has been around and hasn't
changed one word in over two thousnad years..
Also there is evidence of molecular mechanisms in the
cell membranes that can amplify small
changes in the field to produce large
changes in neural activity.13
On the other hand, earlier tests of Kohler's theory found that interference with electrical gradients over the cortex had no effect on behavioral measures (see note 11 for reference to these studies
On the other hand, earlier tests of Kohler's theory found that interference with electrical gradients over the cortex had no effect
on behavioral measures (see note 11 for reference to these studies
on behavioral measures (see note 11 for reference to these studies).
Every individual part may
change and pass away, like
cells in a body, but the one self goes
on.
OK, here we go: Get a new hobby, be physically fit, get plenty of rest, go
on a personal retreat, start mountain biking, don't turn
on your computer or
cell phone for one day a week, go to a creative leader conference and read the book 51 Ways for Revolutionary, Creative, Cutting - Edge, Innovative, Futuristic, Trailblazing, Missional, Catalytic, Groundbreaking, World -
Changing Leaders to Stay Inspired.
To alter a person's germ
cells is to make a
change that may be passed
on through generations of descendants.
Some of the
changes include automated electronic sensors to ensure
cell checks, an
on - duty nurse or EMT at all times and additional funds for jail intaking, inmate screening and training for police there.
And let's remember that evolution, while it's a theory, is a theory about the beginning and the transformation of life based
on things we have observed, namely that
cells change and mutate and that those mutations can produce
cells that are unique and new, and that it would follow that it's possible for molecules to form into single -
celled organisms which mutate and combine into multi-cellular organisms which mutate, adapt, and grow over time into new forms of life.
The load
cells can be equipped with up to 100m cable length and the load
cell cable can be mounted and
changed on - site if necessary.
We ran out of diapers
on day 6 of 8, no problem — contacted the family concierge via the
cell phone provided and she came and got a $ 20 note, sent a bellman to the stores off the resort and brought both the bought diapers, receipt and
change back to me at the pool ---- huge tip provided to her and the bell boy, but worth it!
It has three outer pockets, straps for attaching to just about every type of stroller, a
cell phone pocket
on the strap, an outside rear pocket and a
changing pad
on the inside as well as an inside pocket and a bottle pouch
on the outside for easy access.
Just as the structure of our
cells doesn't
change with our diet, the milk our bodies produce doesn't
change depending
on our nutrition.
It's possible for them to
change depending
on the amount of melanin, which refers to the pigments of color the skin
cells produce.
I was coming onto the highway from the
on - ramp and some jack - ass woman
on her
cell phone driving a red sporty car couldn't be bothered to slow down or
change lanes to let me in.
While you are making adjustments for your
changing shape, there are a lot of
changes going
on inside your womb as your baby, who was just a cluster of
cells a couple of months ago, has organs, nerves, muscles and is looking more like a little person.
These skin
changes are due to hormonal influences
on the skin pigment
cells in these areas.»
A
change in polling foundations (home phones become
cell phones = limitations
on traditional cold calling... and also the shift into online polls).
Changing technology has the Amherst Town Board considering a moratorium
on the installation of new
cell towers, including newer «small
cell» systems
on utility poles.
Scientists must seek a new, more energetic engagement with Americans if they are to overcome public skepticism
on issues ranging from climate
change to stem
cell research, AAAS CEO Alan I. Leshner writes in a commentary in The Chronicle of Higher Education.
Baylin and Johns Hopkins scientist Michelle Vaz, Ph.D., first author
on the study, suspected that the interplay of epigenetic and genetic
changes may occur when normal lung
cells develop into cancer, but, Baylin says, the timing of such
changes was unknown.
«It's not always
changes in the DNA itself, but how the DNA is «decorated» to turn the genes
on and off — called epigenetics — that can determine
cell type.
Faced with an often - hostile Congress, Obama enacted many of his signature policies by executive order — from reversing restrictions
on research with human embryonic stem
cells to helping communities prepare for climate
change.
«In addition,
changes in how the genes are expressed (turned
on or off) could be used in the future to predict how and when the cancer
cells will spread to other parts of the body and how fast they will grow.»
«This is exactly the technology you could use to look for epigenomic
changes in specific
cell types,» says Martienssen, who is also
on the International Human Epigenome Consortium's steering committee.
By measuring how the light has
changed once it emerges through the other side of the slide, the researchers can detect and monitor processes occurring
on the sensor surface, such as
cell division.
«Current therapies in clinical trials are focused
on targeting genetic
changes in tumors and helping to boost one's immune system to fight the cancer
cells.
«The animal and
cell work suggest a number of possibilities, including disruption of sex hormone signaling,
changes in adiponectin release, oxidative damage, and direct effects
on muscle
cells,» Melzer says.
Zika induced
changes that were more focused
on genes involved
on DNA replication and repair, indicating that Zika infection disrupts
cell replication more.
The
cells from the ovaries,
on the other hand, showed no
change in their production of the hormones progesterone and oestradiol.
The creation of the Centre of Regenerative Medicine in Barcelona (CMRB) reflects «a
change in the Spanish public policy regarding derivation and use of human embryonic stem
cells (HESC), based
on a progressive evolution of the public awareness and sensibility of the Spanish [citizenry],» says CMRB Director Juan Carlos Izpisúa Belmonte in an e-mail.
The research is also the first to demonstrate beneficial effects of UDCA
on dopaminergic neurons, the nerve
cells affected in Parkinson's disease, in a fly model of Parkinson's disease which carries the same genetic
change as some patients with the condition.
One would culture thin sheets of meat, seeded by
cells from a living animal,
on a reusable polymer scaffold; the other would grow meat
on small edible beads that stretch with
changes in temperature.
Biochemist Radhey Gupta of McMaster University in Canada proposes that a bacterium and an archaean fused to form the first eukaryote, based
on his analysis of a pair of slow -
changing genes found in what may be one of the oldest
cells with a nucleus, Giardia lamblia.
By analyzing chemical
changes of the IRS - 2 protein in immortalized cultures of human white blood
cells, it determined that IRS - 2 appeared in two different forms — «
on,» which allows the signal to pass through, and «off,» which stops the signal from activating the
cells into M2 macrophages.
Four years ago, the research team of Pedro Herrera (University of Geneva) first cast doubt
on this assumption when they demonstrated that a few alpha
cells in the pancreas of genetically modified diabetic mice
changed into beta
cells.
Sen and his colleagues tested sucralose, a popular low - calorie sweetener,
on stem
cells —
cells that could
change into mature fat, muscle, cartilage or bone
cells — taken from human fat tissue.
Inside the
cell on board Mir, conditions were
changing so fast that they left equilibrium behind.
In the human body
cells turn genes
on and off by means of chemical modifications that
change DNA and related proteins.
Stories
on a possible cause for severe morning sickness and how a mother mouse's care for her pups might trigger
changes to the genomes in their brain
cells
The researchers demonstrated that blocking the PGD enzyme genetically or with a pharmacologic inhibitor reversed the epigenetic reprogramming and malignant gene expression
changes detected in distant metastases, and also strongly inhibited their tumor - forming capacity, with no effect
on normal
cells or peritoneal pancreatic cancer controls.
Experiments
on cells in dishes revealed that chronic exposure to corticosterone
changed the RNA in these vesicles.
As Korch points out,
cells change appearance and function as they grow
on plastic and are chemically manipulated while being studied.
Lee is an expert
on the viral envelope, the dynamic outside surface of a virus that latches onto a
cell, then
changes its shape to let the virus enter and infect the
cell.
When gold nanoparticles combine with red, blue and green glowing proteins, as in this sensor, it's possible to discern drug - induced physical and chemical
changes on a
cell's surface.
And in related experiments, he made tadpoles grow eyes
on their stomachs by
changing the electrical properties of
cells to mimic those associated with eye formation.