However, until now, the germ
cell clusters in mammalian ovaries were thought by most researchers to be a non-functional, evolutionary relic.
Anatomists first discovered
these cell clusters in rabbits around 1874, giving them the name milky spots.
The work also reinforces the importance of finding tumor
cell clusters in the blood as a mechanism of detecting cancer metastasis earlier.
Not exact matches
The research
cluster in B.C. centred around early developer Ballard Power still accounts for more than a quarter of fuel -
cell industry revenues worldwide, said B.C.'s job, tourism and skills training minister, Pat Bell.
The scientists found that when individuals completed a word puzzle, right before a moment of insight, a
cluster of
cells located
in the superior temporal gyrus —
in the right hemisphere of the brain — show significant activity.
The vast majority of the members of the
cluster, however, are small businesses
in the fuel -
cell industry, including suppliers that make pieces of a final product.
The majority of the fuel -
cell industry is rooted
in the Northeast, but fuel -
cell businesses there have only been cooperating for the past decade or so, says Joel M. Rinebold, director of energy initiatives at the Connecticut Center for Advanced Technology, the East Hartford, Conn. - based organization that oversees the
cluster.
These
cells have been found
clustering in sites of anomalies or organ malfunctions such as diabetes, again appearing to try to fix the problem.
Going
in chronological order, I think back to last spring when plant
cells were deciding to be
clusters or not and the weather was great for
cluster primordia development.
Then he remembered things he learned
in psychology classes: A
cluster of
cells in the center of the brain, the nucleus accumbens, gets dosed with the neurotransmitter dopamine when we do something fun, like have sex or eat a doughnut.
Your developing baby doesn't look like a baby yet, but
cells have
clustered in places where your baby's heart and circulatory system will grow as well as where lungs, urinary tract, intestines, brain and entire nervous system will grow.
Alveoli are small
clusters of
cells, and these
cells produce the milk
in the breasts and transport the milk down through the ducts and to the nipples.
A small
cluster of stem
cells in the brain seems to help mice stay young, and injecting extra stem
cells helps them live longer.
After a few days, they divided the
clusters into individual
cells, a small percentage of which grew into so - called blast colonies of up to 400 million
cells, the team reports
in Nature Methods.
Cyclic adenosine monophosphate (cAMP)- dependent protein kinase, labeled with fluorescein and rhodamine on the catalytic and regulatory subunits, respectively, was injected into Aplysia sensory neurons either
in culture or
in intact
cell clusters.
Years ago W.U.'s Holtzman and former colleague Marc Diamond, who has since moved to the University of Texas Southwestern Medical Center, identified tau - binding antibodies that slow the spread of toxic tau
clusters in a lab assay using cultured
cells.
Now, researchers at Washington University School of Medicine
in St. Louis have shown,
in mice, that the virus infects a rare type of intestinal
cell called a tuft
cell, so named because each
cell sports a
cluster of hairlike extensions on its surface.
And
in a basket
cell (above), axon branches, which allow the nerve
cell to send messages to other neurons,
cluster densely around the
cell body.
To get more
cells, researchers from Advanced
Cell Technology in Worcester, Mass., grew clusters of human embryonic cells in a precise cocktail of growth factors and other cell - regulating chemicals that took several years to work out, says Robert Lanza, the firm's vice president of research and scientific developm
Cell Technology
in Worcester, Mass., grew
clusters of human embryonic
cells in a precise cocktail of growth factors and other
cell - regulating chemicals that took several years to work out, says Robert Lanza, the firm's vice president of research and scientific developm
cell - regulating chemicals that took several years to work out, says Robert Lanza, the firm's vice president of research and scientific development.
At the same time, researchers have found that much smaller protein
clusters called oligomers — made of only a few copies of these proteins — can be highly toxic to motor neuron - like
cells grown
in the lab and thus are more likely to be the chief causes of brain -
cell death
in these diseases.
One lab test showed a single
cell moving a distance three times its diameter and joining with a small cancerous
cluster in just four hours.
Fanconi anemia (FA) is a genomic instability syndrome caused by mutations inside a
cluster of proteins normally responsible for DNA repair
in cells.
Still, how melanoma
cells join into tumors — whether by individual
cells coming together or small or large
clusters of
cells doing so — follows the same pattern as breast tissue cancer
cells: Cables are extended to reel
in other
cells or
clusters.
Without sufficient vasculature
in the
clusters, the
cells in the center don't survive.
Ordinarily, fish
cells containing melanin are «well organized» and
clustered in tight groups throughout the lower skin, or dermis.
Sensing small increases
in CO2, the carotid body, a small
cluster of
cells in the neck, spurs big increases
in breathing to remove excess CO2 and keep a person out of trouble.
Pcdhαc2 is found
in a
cluster of genes that contain the blueprints for proteins that protrude from the surface of
cells.
When the NK
cell is activated, the receptor
clusters change
in size and density, which could help NK
cells recognize and eliminate infected
cells — but spare healthy ones — next time around.
Now, Johns Hopkins scientists report direct evidence
in mice for how those
cell clusters control sleep and relay light cues about night and day throughout the body.
«Because 85 percent of people
in the study reported extending the antenna during calls, we might have expected to find a disproportionate
cluster of tumors behind the eye and the ear on the side the
cell phone was used since radiation emission is highest at the antenna,» says co-author Mark Malkin, a neuro - oncologist at Memorial Sloan - Kettering Cancer Center.
Plakoglobin is a component of two important structures involved
in cell - to -
cell adhesion, and the investigators found that suppressing its expression caused CTC
clusters to fall apart, reducing their metastatic potential, and also disrupted
cell - to -
cell contact between breast cancer
cells but not normal breast tissue.
For instance, ZBTB48 KO (knock - out)
cells loose the expression of MTFP1 leading to defects
in the mitochondrial network with mitochondria
clustering around the nucleus instead of being widely spread throughout the
cell.
«We found that the genes for both antibiotic synthesis and self protection
in Strain 115 are conveniently
clustered on a compact DNA molecule [a plasmid] that replicates itself as a small circle within the
cells of Strain 115,» says Griffitts.
The new locus they have identified is near a
cluster of genes which code for proteins called «glycophorins» that are involved
in the malaria parasite's invasion of red blood
cells.
Although
cell - to -
cell infection does result
in release of abundant solo viral particles, direct transmission from HIV - infected immune
cells to other
cells — which can then replicate
in clusters of these
cells — is a much more efficient route to quickly spread the virus, researchers say.
To understand how these multi-colored lesions originated they examined blood from these mice and found that tumor
cells in circulation frequently occurred as
clusters comprised of different colored cancer
cells.
In Parkinson's disease, they are used to turn down the excessive firing of discrete
clusters of nerve
cells that control movement.
But according to Michael McKeown, a developmental geneticist at the Salk Institute
in La Jolla, California, fru's presence
in nine small
clusters of fly nerve
cells — including several previously mapped by Hall as «courtship centers» — may begin to give researchers «a handle on how the neural circuits that generate complex behaviors are put together.»
Until now, the 1.9 billion year old Grypania fossils, found
in Michigan, were widely seen as the first
clusters of organised and communicating
cells.
Taste
cells are located
in clusters called taste buds, which
in turn are found
in papillae, the raised bumps visible on the tongue's surface.
Transplantation of pancreatic islets —
cell clusters that contain insulin - producing
cells — prevents severe, potentially life - threatening drops
in blood sugar
in people with type 1 diabetes, according to new research.
While biomedical researchers have had some successes
in repairing peripheral nerves and nerve
clusters outside the brain and spinal cord
in humans, there currently is no effective way to regenerate broken nerve
cells in the central nervous system, said Xue.
New clinical trial results show that transplantation of pancreatic islets —
cell clusters that contain insulin - producing
cells — prevents severe, potentially life - threatening drops
in blood sugar
in people with type 1 diabetes.
Previous research has shown that cancer
cells traveling
in clusters have a better chance of spreading than loners do (SN: 1/10/15, p. 9).
Reported
in Nature Methods today, the new open source computer tool called Single
Cell Consensus Clustering (SC3) was shown to be more accurate and robust than existing methods of analysing single - cell RNA sequence data, and is freely available for researchers to
Cell Consensus
Clustering (SC3) was shown to be more accurate and robust than existing methods of analysing single -
cell RNA sequence data, and is freely available for researchers to
cell RNA sequence data, and is freely available for researchers to use.
We identified distinct
clusters of CD4 - CTL effector and precursor
cells in the TEMRA subset; the precursor
cells shared TCR clonotypes with CD4 - CTL effectors and were distinguished by high expression of the interleukin - 7 receptor.
Prabhakar and colleagues from the University of Chicago, the Illinois Institute of Technology, Beth Israel Deaconess Medical Center (Boston), and Johns Hopkins University (Baltimore), focused on the carotid bodies, a tiny
cluster of
cells embedded
in the left and right carotid arteries, which pass through the neck.
In 30 fish, Kaufman spotted a small cluster of green - glowing cells about the size of the head of a Sharpie marker — and in all 30 cases, these grew into melanoma
In 30 fish, Kaufman spotted a small
cluster of green - glowing
cells about the size of the head of a Sharpie marker — and
in all 30 cases, these grew into melanoma
in all 30 cases, these grew into melanomas.
One theory is that these protein
clusters create pores
in nerve
cell membranes that allow ions to travel
in and out uncontrollably.
As tumors grow and develop, they shed micro-metastases,
clusters of a few
cells that take up residence
in far - flung organs such as the brain, liver and bone.