Sentences with phrase «cell compartments»
The phrase "cell compartments" refers to the different sections within a cell that have specific functions and are separated by boundaries. These compartments help in organizing the cell's activities so that different tasks can be performed efficiently. Full definition
However, the breast stem cell compartment remains poorly characterized due to the lack of reliable techniques for their identification and isolation.
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These events are directed by specialized proteins called ion channels that allow the flow of calcium ions in and out of cells and among cell compartments.
All eukaryotes, including plants and animals, store their genetic material in cell compartments called nuclei.
The in vivo role of 4 - 1BBL / 4 - 1BB has been addressed in various infectious model systems with bacteria or viruses where in general the molecules control memory development in the CD4 or CD8 T cell compartment, although the requirement for these molecules varies depending on the pathogen.
To learn more about this research, please view the full research report entitled «Regulated selection of germinal center cells into the memory B cell compartment» at this page of the Nature Immunology website.
Previously, we have described a number of practical considerations that should be taken into account when deciding where to place an FP within a fusion construct [1,2], i.e. positioning of the FP sequence relative to cell compartment targeting sequences, which often have absolute position requirements.
One hypothesis is that RNA molecules encoding proteins necessary for plasticity are stored in cell compartments close to the synapses, poised to be translated into proteins when needed.
The macrophage engulfs bacteria and immediately traps them in a separate cell compartment, or vesicle.
Exosomes form inside cell compartments and release outside the cell when these compartments fuse with the cell's surrounding membrane.
Furthermore, translocation of several cholesterogenic enzymes from the endoplasmic reticulum to other cell compartments can occur under various conditions, thereby regulating levels and sites of intracellular cholesterol accumulation.
In fact, the etiology of several neurodevelopmental pathologies seems to be linked to defects in the assembly of the mitotic spindle in the neural stem cell compartment during neurogenesis.
Similarly, IFN - γ blockade did not affect the expansion of gp33 - specific IFN - γ + CD8 T cells (Fig. 4B) or gp33 - specific TNF - α + CD8 T cells (Fig. 4C), although immunized mice continued to have an increased percentage of cytokine - producing cells within the total CD8 T cell compartment.
Another possibility is that the high frequency of these potent antibodies in the memory B cell compartment may have resulted in rapid resolution of infection, precluding the development of a high serological response.
-RSB-, i.e. positioning of the FP sequence relative to cell compartment targeting sequences, which often have absolute position requirements.
We are investigating the molecular mechanisms governing maintenance of the stem cell compartment in normal tissues and how these mechanisms are subverted in cancer.
«We believe that our experiments provide the first example of a factor that both expands the intestinal stem cell compartment and builds a niche.»
Professor Vorholt and her research group took the system a stage further, allowing material to be extracted from the cell compartment as well.
Other researchers had suggested that the death of beta cells associated with type 2 diabetes may be due to stress in a cell compartment called the endoplasmic reticulum (ER).
This is the cell compartment that breaks up used proteins into its basic amino acids.
Ge, Q., Hu, H., Eisen, H.N. & Chen, J. Different contributions of thymopoiesis and homeostasis - driven proliferation to the reconstitution of naive and memory T cell compartments.
Proliferation Drives Aging - Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.
In the subcellular part of the atlas, detailed information is displayed on where in the cell compartment a protein can be found, thereby providing a link towards the understanding of the cellular function of a particular protein.
We demonstrated that this device could reduce the KLRG1 - positive CD8 cell count in aged mouse blood by a factor of 7.3 relative to the total CD8 cell compartment, reaching a level typically seen only in very young animals.
The first of this week's review articles from the lab of Umberto Galderisi (Campania University, Naples, Italy) discusses the effects of low dose ionizing radiation (LDIR) on the biology of stem cell compartments.
However, close examination of human ES cell cultures has revealed significant heterogeneity in the stem cell compartment.
Residing in the epithelial cells that line our skin and gut are specialised T cell compartments that run tight immune surveillance on local tissues.
Two weeks following surgery the naive αβ T cell compartment and the Ccr6 — Vγ4 + T cells had achieved full chimerism, whereas the innate - like lymphocytes showed only limited exchange between the paired mice (Figure 2C).
Sensory ability arises through a morphogenetic process whereby intricate cytoskeleton polarization produces and orients the stereocilia bundle, the cell compartment where transduction occurs.
For this project, we will use this property against the tumor by modulating factors that support the self - renewal of the stem cell compartment and by inducing their terminal differentiation along alternate pathways that have reduced malignant potential.